Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes COPS4
  • Mouse genes Cops4
  • Rat genes Cops4
  • Zfish genes cops4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cops4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	COPS4	IPI	UniProtKB:Q0VDD7	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	COPS4	IPI	UniProtKB:Q8N6Y0	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	COPS4	IPI	UniProtKB:Q7L5N1	Human	PMID:19615732
Molecular Function	GO:0005515	protein binding	COPS4	IPI	UniProtKB:P01100	Human	PMID:20195357
Molecular Function	GO:0005515	protein binding	COPS4	IPI	UniProtKB:O14656	Human	PMID:21102408
Molecular Function	GO:0005515	protein binding	COPS4	IPI	UniProtKB:Q8WXE9	Human	PMID:21102408
Molecular Function	GO:0005515	protein binding	COPS4	IPI	UniProtKB:Q7L5N1	Human	PMID:21145461
Molecular Function	GO:0005515	protein binding	COPS4	IPI	UniProtKB:Q7L5N1	Human	PMID:25043011
Molecular Function	GO:0005515	protein binding	COPS4	IPI	UniProtKB:Q8N6Y0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	COPS4	IPI	UniProtKB:Q15831	Human	PMID:25852190
Molecular Function	GO:0005515	protein binding	COPS4	IPI	UniProtKB:Q03468	Human	PMID:26030138
Molecular Function	GO:0005515	protein binding	COPS4	IPI	UniProtKB:P08727	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	COPS4	IPI	UniProtKB:Q8N6Y0	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	COPS4	IPI	UniProtKB:Q7L5N1	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	COPS4	IPI	UniProtKB:O75381	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	COPS4	IPI	UniProtKB:Q7L5N1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	COPS4	IPI	UniProtKB:Q9Y5F1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	COPS4	IPI	UniProtKB:Q15831	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	COPS4	IPI	UniProtKB:Q9BVL2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	COPS4	IPI	UniProtKB:Q15831	Human	PMID:34591612
Molecular Function	GO:0005515	protein binding	Cops4	IPI	UniProtKB:Q9QXJ2	Mouse	MGI:MGI:3688344|PMID:15102471
Molecular Function	GO:0005515	protein binding	Cops4	IPI	PR:P61202	Mouse	PMID:9707402
Molecular Function	GO:0005515	protein binding	Cops4	IPI	PR:Q8VBV7	Mouse	PMID:9707402
Molecular Function	GO:0005515	protein binding	Cops4	IPI	PR:Q99LD4	Mouse	PMID:9707402
Molecular Function	GO:0005515	protein binding	Cops4	IPI	PR:O35864	Mouse	PMID:9707402
Molecular Function	GO:0005515	protein binding	Cops4	IPI	PR:O88543	Mouse	PMID:9707402
Molecular Function	GO:0005515	protein binding	Cops4	IPI	PR:O88545	Mouse	PMID:9707402
Molecular Function	GO:0005515	protein binding	Cops4	IPI	UniProtKB:D4AB66	Rat	PMID:21102408|RGD:8554353
Cellular Component	GO:0030054	cell junction	COPS4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0008180	COP9 signalosome	COPS4	IPI		Human	PMID:25043011
Cellular Component	GO:0008180	COP9 signalosome	COPS4	IDA		Human	PMID:18850735
Cellular Component	GO:0008180	COP9 signalosome	Cops4	IDA		Mouse	PMID:9707402
Cellular Component	GO:0005737	cytoplasm	COPS4	IDA		Human	PMID:24421388
Cellular Component	GO:0016607	nuclear speck	COPS4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	COPS4	HDA		Human	PMID:21630459
Cellular Component	GO:0005634	nucleus	COPS4	IDA		Human	PMID:24421388
Cellular Component	GO:0008021	synaptic vesicle	COPS4	IDA		Human	PMID:21102408
Cellular Component	GO:0008021	synaptic vesicle	Cops4	IDA		Rat	PMID:21102408|RGD:8554353
Biological Process	GO:0000338	protein deneddylation	COPS4	IDA		Human	PMID:19141280
Biological Process	GO:0000338	protein deneddylation	COPS4	IMP		Human	PMID:21102408

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern