Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CORIN
  • Mouse genes Corin
  • Rat genes Corin
  • Zfish genes corin
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Corin

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004175	endopeptidase activity	CORIN	IMP		Human	PMID:20489134
Molecular Function	GO:0005515	protein binding	CORIN	IPI	UniProtKB:O00501	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CORIN	IPI	UniProtKB:P54849	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CORIN	IPI	UniProtKB:Q13520	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CORIN	IPI	UniProtKB:Q8TED1	Human	PMID:32296183
Molecular Function	GO:0004252	serine-type endopeptidase activity	CORIN	IDA		Human	PMID:10880574
Molecular Function	GO:0004252	serine-type endopeptidase activity	CORIN	IDA		Human	PMID:21763278
Molecular Function	GO:0004252	serine-type endopeptidase activity	Corin	IMP		Mouse	MGI:MGI:5319621|PMID:11884416
Cellular Component	GO:0015629	actin cytoskeleton	CORIN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0009986	cell surface	Corin	IDA		Mouse	PMID:17670789
Cellular Component	GO:0031410	cytoplasmic vesicle	Corin	IDA		Rat	PMID:20613715|RGD:8553515
Cellular Component	GO:0016604	nuclear body	CORIN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	CORIN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Corin	IDA		Rat	PMID:20613715|RGD:8553515
Biological Process	GO:0007565	female pregnancy	CORIN	IMP		Human	PMID:22437503
Biological Process	GO:0007565	female pregnancy	Corin	IMP		Mouse	MGI:MGI:5319447|PMID:22437503
Biological Process	GO:0016486	peptide hormone processing	CORIN	IDA		Human	PMID:10880574
Biological Process	GO:0016486	peptide hormone processing	Corin	IMP		Mouse	MGI:MGI:3530681|PMID:15637153
Biological Process	GO:0016486	peptide hormone processing	Corin	IMP		Mouse	MGI:MGI:5319621|PMID:11884416
Biological Process	GO:0016486	peptide hormone processing	Corin	IMP		Mouse	MGI:MGI:5319447|PMID:22437503
Biological Process	GO:0008217	regulation of blood pressure	Corin	IMP		Mouse	MGI:MGI:5427566|PMID:22418978
Biological Process	GO:0008217	regulation of blood pressure	Corin	IMP		Rat	PMID:20613715|RGD:8553515
Biological Process	GO:0035813	regulation of renal sodium excretion	Corin	IMP		Mouse	MGI:MGI:5427566|PMID:22418978
Biological Process	GO:0035813	regulation of renal sodium excretion	Corin	IMP		Rat	PMID:20613715|RGD:8553515
Biological Process	GO:0003050	regulation of systemic arterial blood pressure by atrial natriuretic peptide	CORIN	IMP		Human	PMID:22437503
Biological Process	GO:0003050	regulation of systemic arterial blood pressure by atrial natriuretic peptide	Corin	IMP		Mouse	MGI:MGI:5319447|PMID:22437503
Biological Process	GO:0003050	regulation of systemic arterial blood pressure by atrial natriuretic peptide	Corin	IMP		Mouse	MGI:MGI:3530681|PMID:15637153

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern