Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CORO1B
  • Mouse genes Coro1b
  • Rat genes Coro1b
  • Zfish genes coro1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Coro1b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051015	actin filament binding	CORO1B	IDA		Human	PMID:17456547
Molecular Function	GO:0051015	actin filament binding	CORO1B	IMP		Human	PMID:22364218
Molecular Function	GO:0071933	Arp2/3 complex binding	CORO1B	IDA		Human	PMID:16027158
Molecular Function	GO:0071933	Arp2/3 complex binding	CORO1B	IDA		Human	PMID:18775315
Molecular Function	GO:0071933	Arp2/3 complex binding	CORO1B	IPI	UniProtKB:P85970	Human	PMID:22619279
Molecular Function	GO:0071933	Arp2/3 complex binding	Coro1b	IPI	RGD:1305848|RGD:2155	Rat	PMID:18775315|RGD:11530062
Molecular Function	GO:0071933	Arp2/3 complex binding	Coro1b	IPI	UniProtKB:P85970	Rat	PMID:22619279|RGD:10047170
Molecular Function	GO:0045296	cadherin binding	CORO1B	HDA		Human	PMID:25468996
Molecular Function	GO:0008092	cytoskeletal protein binding	Coro1b	IPI	RGD:1305848	Rat	PMID:22619279|RGD:10047170
Molecular Function	GO:0042802	identical protein binding	CORO1B	IDA		Human	PMID:16027158
Molecular Function	GO:0005515	protein binding	CORO1B	IPI	UniProtKB:O15144	Human	PMID:16027158
Molecular Function	GO:0005515	protein binding	CORO1B	IPI	UniProtKB:O15144	Human	PMID:17350576
Molecular Function	GO:0005515	protein binding	CORO1B	IPI	UniProtKB:Q8WYL5	Human	PMID:17350576
Molecular Function	GO:0005515	protein binding	CORO1B	IPI	UniProtKB:P54274	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	CORO1B	IPI	UniProtKB:Q9ULV4	Human	PMID:26655834
Molecular Function	GO:0005515	protein binding	CORO1B	IPI	UniProtKB:Q9ULV4	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CORO1B	IPI	UniProtKB:Q969G2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Coro1b	IPI	PR:Q9CVB6	Mouse	PMID:18836449
Molecular Function	GO:0044877	protein-containing complex binding	Coro1b	IPI	RGD:1305848|RGD:1345208	Rat	PMID:17350576|RGD:11567223
Cellular Component	GO:0005884	actin filament	CORO1B	IDA		Human	PMID:18775315
Cellular Component	GO:0031252	cell leading edge	CORO1B	IDA		Human	PMID:16027158
Cellular Component	GO:0031252	cell leading edge	CORO1B	IDA		Human	PMID:17456547
Cellular Component	GO:0031252	cell leading edge	Coro1b	IDA		Rat	PMID:16027158|RGD:11534986
Cellular Component	GO:0071944	cell periphery	CORO1B	IDA		Human	PMID:22619279
Cellular Component	GO:0071944	cell periphery	Coro1b	IDA		Rat	PMID:22619279|RGD:10047170
Cellular Component	GO:0005737	cytoplasm	CORO1B	IDA		Human	PMID:23667561
Cellular Component	GO:0005737	cytoplasm	CORO1B	IDA		Human	PMID:25468996
Cellular Component	GO:0005829	cytosol	CORO1B	IDA		Human	PMID:22619279
Cellular Component	GO:0005829	cytosol	Coro1b	IDA		Rat	PMID:22619279|RGD:10047170
Cellular Component	GO:0070062	extracellular exosome	CORO1B	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	CORO1B	HDA		Human	PMID:23533145
Cellular Component	GO:0005925	focal adhesion	CORO1B	HDA		Human	PMID:21423176
Cellular Component	GO:0030027	lamellipodium	CORO1B	IDA		Human	PMID:22619279
Cellular Component	GO:0030027	lamellipodium	CORO1B	IDA		Human	PMID:23667561
Cellular Component	GO:0030027	lamellipodium	Coro1b	IDA		Rat	PMID:22619279|RGD:10047170
Cellular Component	GO:0048471	perinuclear region of cytoplasm	CORO1B	IDA		Human	PMID:22619279
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Coro1b	IDA		Rat	PMID:22619279|RGD:10047170
Cellular Component	GO:0005886	plasma membrane	CORO1B	IDA		Human	PMID:15800061
Cellular Component	GO:0001725	stress fiber	CORO1B	IDA		Human	PMID:16027158
Cellular Component	GO:0001725	stress fiber	CORO1B	IDA		Human	PMID:22619279
Cellular Component	GO:0001725	stress fiber	Coro1b	IDA		Rat	PMID:22619279|RGD:10047170
Biological Process	GO:0030036	actin cytoskeleton organization	CORO1B	IDA		Human	PMID:18775315
Biological Process	GO:0090135	actin filament branching	CORO1B	IDA		Human	PMID:18775315
Biological Process	GO:0051017	actin filament bundle assembly	CORO1B	IDA		Human	PMID:17456547
Biological Process	GO:0016477	cell migration	CORO1B	IDA		Human	PMID:16027158
Biological Process	GO:0036120	cellular response to platelet-derived growth factor stimulus	CORO1B	IMP		Human	PMID:22619279
Biological Process	GO:0036120	cellular response to platelet-derived growth factor stimulus	Coro1b	IDA		Rat	PMID:22619279|RGD:10047170
Biological Process	GO:0036120	cellular response to platelet-derived growth factor stimulus	Coro1b	IMP		Rat	PMID:22619279|RGD:10047170
Biological Process	GO:0035767	endothelial cell chemotaxis	CORO1B	IDA		Human	PMID:23667561
Biological Process	GO:0035767	endothelial cell chemotaxis	CORO1B	IMP		Human	PMID:23667561
Biological Process	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation	CORO1B	IDA		Human	PMID:17350576
Biological Process	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation	CORO1B	IDA		Human	PMID:18775315
Biological Process	GO:2000393	negative regulation of lamellipodium morphogenesis	Coro1b	IMP		Rat	PMID:22619279|RGD:10047170
Biological Process	GO:0071672	negative regulation of smooth muscle cell chemotaxis	CORO1B	IMP		Human	PMID:22619279
Biological Process	GO:0071672	negative regulation of smooth muscle cell chemotaxis	Coro1b	IMP		Rat	PMID:22619279|RGD:10047170
Biological Process	GO:2000394	positive regulation of lamellipodium morphogenesis	CORO1B	IDA		Human	PMID:17350576
Biological Process	GO:0070528	protein kinase C signaling	Coro1b	IDA		Rat	PMID:16027158|RGD:11534986
Biological Process	GO:1902463	protein localization to cell leading edge	CORO1B	IDA		Human	PMID:17350576
Biological Process	GO:0031529	ruffle organization	CORO1B	IDA		Human	PMID:16027158
Biological Process	GO:0042060	wound healing	CORO1B	IDA		Human	PMID:23667561

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern