Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CORO1C
  • Mouse genes Coro1c
  • Rat genes Coro1c
  • Zfish genes coro1ca,coro1cb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Coro1c

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051015	actin filament binding	CORO1C	IMP		Human	PMID:22364218
Molecular Function	GO:0005515	protein binding	CORO1C	IPI	UniProtKB:Q9P258	Human	PMID:25074804
Molecular Function	GO:0005515	protein binding	CORO1C	IPI	UniProtKB:Q9BR76	Human	PMID:26655834
Molecular Function	GO:0005515	protein binding	CORO1C	IPI	UniProtKB:Q9BR76	Human	PMID:28514442
Molecular Function	GO:0031267	small GTPase binding	Coro1c	IPI	UniProtKB:P63001	Mouse	MGI:MGI:5621257|PMID:25074804
Cellular Component	GO:0015629	actin cytoskeleton	CORO1C	IDA		Human	PMID:22364218
Cellular Component	GO:0005856	cytoskeleton	Coro1c	IDA		Mouse	MGI:MGI:5621257|PMID:25074804
Cellular Component	GO:0010008	endosome membrane	CORO1C	IDA		Human	PMID:30220460
Cellular Component	GO:0016600	flotillin complex	Coro1c	IDA		Mouse	MGI:MGI:5621257|PMID:25074804
Cellular Component	GO:0005925	focal adhesion	CORO1C	HDA		Human	PMID:21423176
Cellular Component	GO:0030027	lamellipodium	CORO1C	IDA		Human	PMID:22364218
Cellular Component	GO:0016328	lateral plasma membrane	CORO1C	IDA		Human	PMID:25074804
Cellular Component	GO:0031982	vesicle	CORO1C	IDA		Human	PMID:25074804
Biological Process	GO:0090630	activation of GTPase activity	Coro1c	IGI	UniProtKB:Q8BK67	Mouse	MGI:MGI:5621257|PMID:25074804
Biological Process	GO:0090630	activation of GTPase activity	Coro1c	IMP		Mouse	MGI:MGI:5621257|PMID:25074804
Biological Process	GO:0022038	corpus callosum development	Coro1c	IMP	MGI:4419168	Mouse	PMID:29078390
Biological Process	GO:0016197	endosomal transport	CORO1C	IDA		Human	PMID:30220460
Biological Process	GO:0140285	endosome fission	CORO1C	IDA		Human	PMID:30220460
Biological Process	GO:0097750	endosome membrane tubulation	CORO1C	IDA		Human	PMID:30220460
Biological Process	GO:0045184	establishment of protein localization	Coro1c	IMP		Mouse	MGI:MGI:5621257|PMID:25074804
Biological Process	GO:0045184	establishment of protein localization	Coro1c	IGI	UniProtKB:Q8BK67	Mouse	MGI:MGI:5621257|PMID:25074804
Biological Process	GO:0090148	membrane fission	CORO1C	IDA		Human	PMID:30220460
Biological Process	GO:0010633	negative regulation of epithelial cell migration	CORO1C	IMP		Human	PMID:19913511
Biological Process	GO:0051895	negative regulation of focal adhesion assembly	CORO1C	IMP		Human	PMID:19913511
Biological Process	GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation	CORO1C	IMP		Human	PMID:19913511
Biological Process	GO:0001933	negative regulation of protein phosphorylation	CORO1C	IMP		Human	PMID:19913511
Biological Process	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading	CORO1C	IMP		Human	PMID:19913511
Biological Process	GO:0001755	neural crest cell migration	CORO1C	IMP		Human	PMID:25074804
Biological Process	GO:0001755	neural crest cell migration	coro1ca	IMP		Zfish	PMID:25074804|ZFIN:ZDB-PUB-140731-3
Biological Process	GO:2000394	positive regulation of lamellipodium morphogenesis	CORO1C	IMP		Human	PMID:19913511
Biological Process	GO:0010632	regulation of epithelial cell migration	CORO1C	IGI	UniProtKB:Q05397	Human	PMID:19913511
Biological Process	GO:0010762	regulation of fibroblast migration	Coro1c	IMP		Mouse	MGI:MGI:5621257|PMID:25074804
Biological Process	GO:0051893	regulation of focal adhesion assembly	CORO1C	IGI	UniProtKB:Q05397	Human	PMID:19913511
Biological Process	GO:0001932	regulation of protein phosphorylation	CORO1C	IGI	UniProtKB:Q05397	Human	PMID:19913511
Biological Process	GO:1900027	regulation of ruffle assembly	Coro1c	IGI	UniProtKB:Q8BK67	Mouse	MGI:MGI:5621257|PMID:25074804
Biological Process	GO:1900024	regulation of substrate adhesion-dependent cell spreading	CORO1C	IGI	UniProtKB:Q05397	Human	PMID:19913511
Biological Process	GO:0021591	ventricular system development	Coro1c	IMP	MGI:4419168	Mouse	PMID:29078390

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern