Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes COX17
  • Mouse genes Cox17
  • Rat genes Cox17
  • Zfish genes cox17
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cox17

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016531	copper chaperone activity	COX17	IMP		Human	PMID:19393246
Molecular Function	GO:0005507	copper ion binding	Cox17	IDA		Mouse	PMID:12370308
Molecular Function	GO:1903136	cuprous ion binding	COX17	IDA		Human	PMID:18093982
Molecular Function	GO:0008047	enzyme activator activity	Cox17	IMP	MGI:MGI:2388937	Mouse	PMID:12370308
Molecular Function	GO:0043167	ion binding	COX17	EXP		Human	PMID:18093982
Molecular Function	GO:0005515	protein binding	COX17	IPI	UniProtKB:Q9BW62	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	COX17	IPI	UniProtKB:O75880	Human	PMID:18458339
Molecular Function	GO:0005515	protein binding	COX17	IPI	UniProtKB:Q8N4Q1-1	Human	PMID:19182799
Molecular Function	GO:0005515	protein binding	COX17	IPI	UniProtKB:Q9BW62	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	COX17	IPI	UniProtKB:O75880	Human	PMID:29568061
Molecular Function	GO:0005515	protein binding	COX17	IPI	UniProtKB:P60410	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	COX17	IPI	UniProtKB:Q7Z699	Human	PMID:32814053
Cellular Component	GO:0005737	cytoplasm	COX17	IDA		Human	PMID:19393246
Cellular Component	GO:0005758	mitochondrial intermembrane space	COX17	IDA		Human	PMID:19393246
Cellular Component	GO:0005739	mitochondrion	Cox17	HDA		Mouse	PMID:18614015
Biological Process	GO:0007420	brain development	Cox17	IEP		Rat	PMID:11054125|RGD:632610
Biological Process	GO:0071280	cellular response to copper ion	cox17	IMP	ZFIN:ZDB-GENO-200806-4	Zfish	PMID:31662245
Biological Process	GO:0071280	cellular response to copper ion	cox17	IMP	ZFIN:ZDB-GENO-200806-5	Zfish	PMID:31662245
Biological Process	GO:0007507	heart development	Cox17	IEP		Rat	PMID:11054125|RGD:632610
Biological Process	GO:0033617	mitochondrial cytochrome c oxidase assembly	COX17	IMP		Human	PMID:19393246
Biological Process	GO:0008284	positive regulation of cell population proliferation	COX17	IMP		Human	PMID:19393246
Biological Process	GO:1904960	positive regulation of cytochrome-c oxidase activity	COX17	IMP		Human	PMID:19393246
Biological Process	GO:0046688	response to copper ion	cox17	IDA		Zfish	PMID:17855494
Biological Process	GO:0051238	sequestering of metal ion	COX17	EXP		Human	PMID:18093982

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern