Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes COX18
  • Mouse genes Cox18
  • Rat genes Cox18
  • Zfish genes cox18
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cox18

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0032977	membrane insertase activity	COX18	IGI	UniProtKB:P53239	Human	PMID:16911509
Molecular Function	GO:0032977	membrane insertase activity	COX18	IDA		Human	PMID:28330871
Molecular Function	GO:0005515	protein binding	COX18	IPI	UniProtKB:O75880|UniProtKB:P00403|UniProtKB:Q5RI15	Human	PMID:28330871
Cellular Component	GO:0005743	mitochondrial inner membrane	COX18	IDA		Human	PMID:16212937
Cellular Component	GO:0005739	mitochondrion	Cox18	HDA		Mouse	PMID:18614015
Biological Process	GO:0033617	mitochondrial cytochrome c oxidase assembly	COX18	IMP		Human	PMID:28330871
Biological Process	GO:0032979	protein insertion into mitochondrial inner membrane from matrix	COX18	IDA		Human	PMID:28330871
Biological Process	GO:0051204	protein insertion into mitochondrial membrane	COX18	IGI	UniProtKB:P53239	Human	PMID:16911509
Biological Process	GO:0008535	respiratory chain complex IV assembly	COX18	IGI	UniProtKB:P53239	Human	PMID:16911509

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern