Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CPLX3
  • Mouse genes Cplx3
  • Rat genes Cplx3
  • Zfish genes cplx3a,cplx3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cplx3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005326	neurotransmitter transmembrane transporter activity	Cplx3	IMP		Mouse	MGI:MGI:3582382|PMID:15911881
Molecular Function	GO:0000149	SNARE binding	Cplx3	IDA		Mouse	PMID:15911881
Cellular Component	GO:0005829	cytosol	Cplx3	IDA		Mouse	PMID:15911881
Cellular Component	GO:0016020	membrane	Cplx3	IDA		Mouse	MGI:MGI:3582382|PMID:15911881
Cellular Component	GO:0098684	photoreceptor ribbon synapse	Cplx3	IDA		Mouse	PMID:27239031
Cellular Component	GO:0098684	photoreceptor ribbon synapse	Cplx3	IMP		Mouse	PMID:27239031
Cellular Component	GO:0005886	plasma membrane	Cplx3	IDA		Mouse	PMID:15911881
Cellular Component	GO:0048787	presynaptic active zone membrane	Cplx3	IEP		Mouse	PMID:15911881
Cellular Component	GO:0048787	presynaptic active zone membrane	Cplx3	IDA		Mouse	PMID:15911881
Cellular Component	GO:0048787	presynaptic active zone membrane	Cplx3	IMP		Mouse	PMID:15911881
Cellular Component	GO:0048787	presynaptic active zone membrane	Cplx3	IPI		Mouse	PMID:15911881
Cellular Component	GO:0045202	synapse	Cplx3	IDA		Mouse	PMID:15911881
Cellular Component	GO:0030672	synaptic vesicle membrane	Cplx3	IDA		Mouse	PMID:15911881
Cellular Component	GO:0030672	synaptic vesicle membrane	Cplx3	IPI		Mouse	PMID:15911881
Cellular Component	GO:0030672	synaptic vesicle membrane	Cplx3	IMP		Mouse	PMID:15911881
Cellular Component	GO:0030672	synaptic vesicle membrane	Cplx3	IEP		Mouse	PMID:15911881
Biological Process	GO:0030073	insulin secretion	Cplx3	IMP		Mouse	MGI:MGI:3582382|PMID:15911881
Biological Process	GO:0046928	regulation of neurotransmitter secretion	Cplx3	IDA		Mouse	PMID:15911881
Biological Process	GO:0031630	regulation of synaptic vesicle fusion to presynaptic active zone membrane	Cplx3	IDA		Mouse	PMID:27239031
Biological Process	GO:0031630	regulation of synaptic vesicle fusion to presynaptic active zone membrane	Cplx3	IMP		Mouse	PMID:27239031
Biological Process	GO:0016079	synaptic vesicle exocytosis	Cplx3	IMP		Mouse	MGI:MGI:3582382|PMID:15911881

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern