Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CPNE1
  • Mouse genes Cpne1
  • Rat genes Cpne1,Rbm12
  • Zfish genes cpne1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cpne1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005509	calcium ion binding	CPNE1	IMP		Human	PMID:25450385
Molecular Function	GO:0004175	endopeptidase activity	CPNE1	IDA		Human	PMID:18212740
Molecular Function	GO:0042802	identical protein binding	CPNE1	IPI	UniProtKB:Q99829	Human	PMID:18212740
Molecular Function	GO:0051059	NF-kappaB binding	CPNE1	IPI	UniProtKB:Q04206	Human	PMID:18212740
Molecular Function	GO:0001786	phosphatidylserine binding	CPNE1	IDA		Human	PMID:9430674
Molecular Function	GO:0005515	protein binding	CPNE1	IPI	UniProtKB:P26043	Human	PMID:12522145
Molecular Function	GO:0005515	protein binding	CPNE1	IPI	UniProtKB:P60710	Human	PMID:12522145
Molecular Function	GO:0005515	protein binding	CPNE1	IPI	UniProtKB:Q60676	Human	PMID:12522145
Molecular Function	GO:0005515	protein binding	CPNE1	IPI	UniProtKB:Q6ZPJ3	Human	PMID:12522145
Molecular Function	GO:0005515	protein binding	CPNE1	IPI	UniProtKB:Q7TPH6	Human	PMID:12522145
Molecular Function	GO:0005515	protein binding	CPNE1	IPI	UniProtKB:O60504	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CPNE1	IPI	UniProtKB:Q9UPM6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Cpne1	IPI	UniProtKB:Q9JIG7	Mouse	MGI:MGI:5294308|PMID:12522145
Cellular Component	GO:0005737	cytoplasm	CPNE1	IDA		Human	PMID:21087455
Cellular Component	GO:0005737	cytoplasm	CPNE1	IDA		Human	PMID:25450385
Cellular Component	GO:0005829	cytosol	CPNE1	IDA		Human	PMID:12949241
Cellular Component	GO:0005829	cytosol	CPNE1	IDA		Human	PMID:18212740
Cellular Component	GO:0070062	extracellular exosome	CPNE1	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	CPNE1	HDA		Human	PMID:23533145
Cellular Component	GO:0016020	membrane	CPNE1	IDA		Human	PMID:25450385
Cellular Component	GO:0031965	nuclear membrane	CPNE1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	CPNE1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	CPNE1	IDA		Human	PMID:18212740
Cellular Component	GO:0005634	nucleus	CPNE1	IDA		Human	PMID:21087455
Biological Process	GO:0071277	cellular response to calcium ion	CPNE1	IMP		Human	PMID:14674885
Biological Process	GO:0043392	negative regulation of DNA binding	CPNE1	IDA		Human	PMID:18212740
Biological Process	GO:0010629	negative regulation of gene expression	CPNE1	IMP		Human	PMID:18212740
Biological Process	GO:1901223	negative regulation of NIK/NF-kappaB signaling	CPNE1	IMP		Human	PMID:18212740
Biological Process	GO:1990138	neuron projection extension	CPNE1	IDA		Human	PMID:23263657
Biological Process	GO:1990138	neuron projection extension	CPNE1	IMP		Human	PMID:25450385
Biological Process	GO:0045666	positive regulation of neuron differentiation	CPNE1	IDA		Human	PMID:23263657
Biological Process	GO:0045666	positive regulation of neuron differentiation	CPNE1	IMP		Human	PMID:25450385
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	CPNE1	IDA		Human	PMID:23263657
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	CPNE1	IMP		Human	PMID:25450385
Biological Process	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway	CPNE1	IMP		Human	PMID:14674885
Biological Process	GO:0006508	proteolysis	CPNE1	IMP		Human	PMID:18212740
Biological Process	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling	CPNE1	IMP		Human	PMID:14674885

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern