Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CPNE6
  • Mouse genes Cpne6
  • Rat genes Cpne6
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cpne6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001786	phosphatidylserine binding	Cpne6	IDA		Mouse	PMID:9886090
Molecular Function	GO:0005515	protein binding	CPNE6	IPI	UniProtKB:P50222	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	Cpne6	IPI	UniProtKB:Q8K2C7	Mouse	MGI:MGI:5688850|PMID:10403379
Cellular Component	GO:0030424	axon	Cpne6	IDA		Mouse	PMID:9886090
Cellular Component	GO:0045334	clathrin-coated endocytic vesicle	Cpne6	IDA		Mouse	MGI:MGI:5634886|PMID:21087455
Cellular Component	GO:0005737	cytoplasm	Cpne6	IDA		Mouse	MGI:MGI:5634886|PMID:21087455
Cellular Component	GO:0030425	dendrite	Cpne6	IDA		Mouse	PMID:9886090
Cellular Component	GO:0070062	extracellular exosome	CPNE6	HDA		Human	PMID:23533145
Cellular Component	GO:0016020	membrane	Cpne6	IDA		Mouse	PMID:9886090
Cellular Component	GO:0005886	plasma membrane	Cpne6	IDA		Mouse	MGI:MGI:5634886|PMID:21087455
Biological Process	GO:0071277	cellular response to calcium ion	Cpne6	IMP		Mouse	MGI:MGI:5634886|PMID:21087455
Biological Process	GO:1903861	positive regulation of dendrite extension	CPNE6	IDA		Human	PMID:23999003
Biological Process	GO:0098974	postsynaptic actin cytoskeleton organization	Cpne6	IDA		Mouse	PMID:27194588
Biological Process	GO:0098974	postsynaptic actin cytoskeleton organization	Cpne6	IMP		Mouse	PMID:27194588
Biological Process	GO:0098974	postsynaptic actin cytoskeleton organization	Cpne6	EXP		Mouse	PMID:27194588

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern