Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CPOX
  • Mouse genes Cpox
  • Rat genes Cpox
  • Zfish genes cpox
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cpox

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004109	coproporphyrinogen oxidase activity	CPOX	IDA		Human	PMID:7987309
Molecular Function	GO:0004109	coproporphyrinogen oxidase activity	Cpox	IDA		Mouse	PMID:8407975
Molecular Function	GO:0004109	coproporphyrinogen oxidase activity	Cpox	IDA		Rat	PMID:11079369|RGD:1600956
Molecular Function	GO:0042802	identical protein binding	Cpox	IDA		Rat	PMID:11079369|RGD:1600956
Molecular Function	GO:0042803	protein homodimerization activity	CPOX	IDA		Human	PMID:16176984
Molecular Function	GO:0005212	structural constituent of eye lens	Cpox	IMP	MGI:MGI:97287	Mouse	PMID:12470976
Cellular Component	GO:0005829	cytosol	CPOX	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	Cpox	IMP		Mouse	MGI:MGI:4420830|PMID:20080761
Cellular Component	GO:0005743	mitochondrial inner membrane	Cpox	IDA		Rat	PMID:31872|RGD:1600963
Cellular Component	GO:0005758	mitochondrial intermembrane space	Cpox	IDA		Rat	PMID:31872|RGD:1600963
Cellular Component	GO:0005739	mitochondrion	CPOX	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	Cpox	IDA		Mouse	PMID:8407975
Cellular Component	GO:0005739	mitochondrion	Cpox	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Cpox	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Cpox	IDA		Mouse	PMID:15482256
Cellular Component	GO:0005739	mitochondrion	Cpox	IDA		Rat	PMID:3996415|RGD:1599183
Biological Process	GO:0006783	heme biosynthetic process	Cpox	IDA		Mouse	PMID:8407975
Biological Process	GO:0006783	heme biosynthetic process	Cpox	IDA		Rat	PMID:3955059|RGD:1600961
Biological Process	GO:0042541	hemoglobin biosynthetic process	cpox	IMP	ZFIN:ZDB-MRPHLNO-060406-1	Zfish	PMID:16483317
Biological Process	GO:0006782	protoporphyrinogen IX biosynthetic process	Cpox	IDA		Rat	PMID:3814086|RGD:4145128
Biological Process	GO:0046685	response to arsenic-containing substance	Cpox	IEP		Rat	PMID:2916235|RGD:1600960
Biological Process	GO:0010035	response to inorganic substance	Cpox	IEP		Rat	PMID:2289051|RGD:1600959
Biological Process	GO:0017085	response to insecticide	Cpox	IEP		Rat	PMID:6626236|RGD:1600962
Biological Process	GO:0010039	response to iron ion	Cpox	IEP		Rat	PMID:2289051|RGD:1600959
Biological Process	GO:0010288	response to lead ion	Cpox	IEP		Rat	PMID:656697|RGD:4145135
Biological Process	GO:0051597	response to methylmercury	Cpox	IEP		Rat	PMID:2916235|RGD:1600960

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern