Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Cps1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes CPS1
- Mouse genes Cps1
- Rat genes Cps1
- Zfish genes cps1
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cps1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	Cps1	IDA		Rat	PMID:11577071\|RGD:2303524
Molecular Function	GO:0005509	calcium ion binding	Cps1	IPI	PubChem_Compound:6335493	Rat	PMID:9506839\|RGD:4144103
Molecular Function	GO:0004087	carbamoyl-phosphate synthase (ammonia) activity	CPS1	EXP		Human	PMID:6249820
Molecular Function	GO:0004087	carbamoyl-phosphate synthase (ammonia) activity	CPS1	IMP		Human	PMID:8486760
Molecular Function	GO:0004087	carbamoyl-phosphate synthase (ammonia) activity	CPS1	IMP		Human	PMID:9711878
Molecular Function	GO:0004087	carbamoyl-phosphate synthase (ammonia) activity	Cps1	IMP	MGI:MGI:2386969	Mouse	PMID:9862865
Molecular Function	GO:0004087	carbamoyl-phosphate synthase (ammonia) activity	Cps1	IDA		Rat	PMID:11577071\|RGD:2303524
Molecular Function	GO:0004087	carbamoyl-phosphate synthase (ammonia) activity	Cps1	IDA		Rat	PMID:3680220\|RGD:1582379
Molecular Function	GO:0004087	carbamoyl-phosphate synthase (ammonia) activity	Cps1	IDA		Rat	PMID:4062872\|RGD:2300098
Molecular Function	GO:0004087	carbamoyl-phosphate synthase (ammonia) activity	cps1	IMP	ZFIN:ZDB-MRPHLNO-130719-1	Zfish	PMID:23576614
Molecular Function	GO:0004175	endopeptidase activity	Cps1	IDA		Rat	PMID:15304357\|RGD:4144096
Molecular Function	GO:0016595	glutamate binding	Cps1	IPI	PubChem_Compound:185	Rat	PMID:8663466\|RGD:4144107
Molecular Function	GO:0046872	metal ion binding	CPS1	EXP		Human	PMID:26592762
Molecular Function	GO:0072341	modified amino acid binding	CPS1	IDA		Human	PMID:20031578
Molecular Function	GO:0005543	phospholipid binding	Cps1	IPI	PubChem_Compound:5287898	Rat	PMID:1898084\|RGD:4144109
Molecular Function	GO:0005543	phospholipid binding	Cps1	IDA		Rat	PMID:3680220\|RGD:1582379
Molecular Function	GO:0005515	protein binding	CPS1	IPI	UniProtKB:P04049	Human	PMID:12620389
Molecular Function	GO:0005515	protein binding	CPS1	IPI	UniProtKB:P10398	Human	PMID:12620389
Molecular Function	GO:0005515	protein binding	CPS1	IPI	UniProtKB:P63104	Human	PMID:15161933
Molecular Function	GO:0005515	protein binding	CPS1	IPI	UniProtKB:P63104	Human	PMID:20618440
Molecular Function	GO:0005515	protein binding	Cps1	IPI	UniProtKB:Q8K2C6	Mouse	MGI:MGI:3846470\|PMID:19410549
Molecular Function	GO:0044877	protein-containing complex binding	Cps1	IDA		Rat	PMID:17669278\|RGD:2303511
Molecular Function	GO:0036094	small molecule binding	CPS1	EXP		Human	PMID:26592762
Cellular Component	GO:0005737	cytoplasm	Cps1	IDA		Rat	PMID:3527129\|RGD:2303522
Cellular Component	GO:0005743	mitochondrial inner membrane	Cps1	IDA		Rat	PMID:3680220\|RGD:1582379
Cellular Component	GO:0042645	mitochondrial nucleoid	CPS1	IDA		Human	PMID:18063578
Cellular Component	GO:0005739	mitochondrion	Cps1	IDA		Mouse	PMID:6200105
Cellular Component	GO:0005739	mitochondrion	Cps1	IDA		Mouse	PMID:26767982
Cellular Component	GO:0005739	mitochondrion	Cps1	IDA		Mouse	PMID:22402285
Cellular Component	GO:0005739	mitochondrion	Cps1	IDA		Rat	PMID:14561759\|RGD:1580664
Cellular Component	GO:0005730	nucleolus	CPS1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0032991	protein-containing complex	Cps1	IDA		Rat	PMID:17669278\|RGD:2303511
Biological Process	GO:0097272	ammonium homeostasis	cps1	IMP	ZFIN:ZDB-MRPHLNO-130719-1	Zfish	PMID:23576614
Biological Process	GO:0070409	carbamoyl phosphate biosynthetic process	CPS1	IMP		Human	PMID:21120950
Biological Process	GO:0070409	carbamoyl phosphate biosynthetic process	CPS1	IMP		Human	PMID:7416778
Biological Process	GO:0071242	cellular response to ammonium ion	CPS1	IMP		Human	PMID:21120950
Biological Process	GO:0071320	cellular response to cAMP	Cps1	IEP		Rat	PMID:17397987\|RGD:2303516
Biological Process	GO:0044344	cellular response to fibroblast growth factor stimulus	Cps1	IEP		Rat	PMID:12832696\|RGD:4144100
Biological Process	GO:0071377	cellular response to glucagon stimulus	Cps1	IEP		Rat	PMID:8460937\|RGD:4140437
Biological Process	GO:0071400	cellular response to oleic acid	Cps1	IEP		Rat	PMID:8985169\|RGD:2303518
Biological Process	GO:0070365	hepatocyte differentiation	Cps1	IEP		Rat	PMID:12939595\|RGD:4144098
Biological Process	GO:0050667	homocysteine metabolic process	CPS1	IDA		Human	PMID:20031578
Biological Process	GO:0001889	liver development	Cps1	IEP		Rat	PMID:8690412\|RGD:4144072
Biological Process	GO:0007494	midgut development	Cps1	IEP		Rat	PMID:9544996\|RGD:4139911
Biological Process	GO:0055081	monoatomic anion homeostasis	Cps1	IDA		Rat	PMID:4062872\|RGD:2300098
Biological Process	GO:0046209	nitric oxide metabolic process	CPS1	IMP		Human	PMID:14718356
Biological Process	GO:0014075	response to amine	Cps1	IEP		Rat	PMID:2864015\|RGD:2303531
Biological Process	GO:0043200	response to amino acid	Cps1	IEP		Rat	PMID:11738098\|RGD:4144101
Biological Process	GO:0051591	response to cAMP	Cps1	IEP		Rat	PMID:17397987\|RGD:2303516
Biological Process	GO:0051591	response to cAMP	Cps1	IEP		Rat	PMID:6092398\|RGD:2303523
Biological Process	GO:0071548	response to dexamethasone	Cps1	IEP		Rat	PMID:19446026\|RGD:4144092
Biological Process	GO:0032094	response to food	Cps1	IEP		Rat	PMID:15481768\|RGD:2303517
Biological Process	GO:0033762	response to glucagon	Cps1	IEP		Rat	PMID:3754512\|RGD:2303521
Biological Process	GO:0051384	response to glucocorticoid	Cps1	IEP		Rat	PMID:17397987\|RGD:2303516
Biological Process	GO:0051384	response to glucocorticoid	Cps1	IEP		Rat	PMID:8985169\|RGD:2303518
Biological Process	GO:0060416	response to growth hormone	Cps1	IEP		Rat	PMID:9688877\|RGD:1599313
Biological Process	GO:0032496	response to lipopolysaccharide	CPS1	IDA		Human	PMID:15897806
Biological Process	GO:0032496	response to lipopolysaccharide	Cps1	IEP		Rat	PMID:17539997\|RGD:2303515
Biological Process	GO:0034201	response to oleic acid	Cps1	IEP		Rat	PMID:8985169\|RGD:2303518
Biological Process	GO:0042594	response to starvation	Cps1	IEP		Rat	PMID:1979948\|RGD:2303520
Biological Process	GO:0048545	response to steroid hormone	Cps1	IEP		Rat	PMID:9688877\|RGD:1599313
Biological Process	GO:0009636	response to toxic substance	Cps1	IEP		Rat	PMID:14625847\|RGD:4144097
Biological Process	GO:0009636	response to toxic substance	Cps1	IEP		Rat	PMID:20452409\|RGD:4110826
Biological Process	GO:0009410	response to xenobiotic stimulus	Cps1	IEP		Rat	PMID:19135993\|RGD:2303405
Biological Process	GO:0010043	response to zinc ion	Cps1	IEP		Rat	PMID:12840196\|RGD:4144099
Biological Process	GO:0051238	sequestering of metal ion	CPS1	EXP		Human	PMID:26592762
Biological Process	GO:0019433	triglyceride catabolic process	CPS1	IMP		Human	PMID:9711878
Biological Process	GO:0000050	urea cycle	Cps1	IDA		Rat	PMID:3680220\|RGD:1582379
Biological Process	GO:0000050	urea cycle	Cps1	IDA		Rat	PMID:4062872\|RGD:2300098
Biological Process	GO:0000050	urea cycle	cps1	IMP	ZFIN:ZDB-MRPHLNO-130719-1	Zfish	PMID:23576614
Biological Process	GO:0042311	vasodilation	CPS1	IMP		Human	PMID:14718356

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.