Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CPSF3
  • Mouse genes Cpsf3
  • Rat genes Cpsf3
  • Zfish genes cpsf3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cpsf3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004534	5'-3' RNA exonuclease activity	Cpsf3	IDA		Mouse	MGI:MGI:4418605|PMID:18955505
Molecular Function	GO:0046872	metal ion binding	CPSF3	IMP		Human	PMID:30507380
Molecular Function	GO:0005515	protein binding	CPSF3	IPI	UniProtKB:Q9H6E5	Human	PMID:18288197
Molecular Function	GO:0005515	protein binding	CPSF3	IPI	UniProtKB:P33240	Human	PMID:18688255
Molecular Function	GO:0005515	protein binding	CPSF3	IPI	UniProtKB:Q92797	Human	PMID:18688255
Molecular Function	GO:0005515	protein binding	CPSF3	IPI	UniProtKB:Q9P2I0	Human	PMID:18688255
Molecular Function	GO:0005515	protein binding	CPSF3	IPI	UniProtKB:Q9H6E5	Human	PMID:21102410
Molecular Function	GO:0005515	protein binding	CPSF3	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0003723	RNA binding	Cpsf3	IDA		Mouse	MGI:MGI:4418605|PMID:18955505
Molecular Function	GO:0004521	RNA endonuclease activity	CPSF3	IMP		Human	PMID:30507380
Molecular Function	GO:0004521	RNA endonuclease activity	Cpsf3	IDA		Mouse	MGI:MGI:4418605|PMID:18955505
Cellular Component	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex	CPSF3	IDA		Human	PMID:18305108
Cellular Component	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex	CPSF3	IDA		Human	PMID:21102410
Cellular Component	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex	Cpsf3	IDA		Mouse	PMID:16115198
Biological Process	GO:0031124	mRNA 3'-end processing	CPSF3	IMP		Human	PMID:30507380
Biological Process	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage	CPSF3	IDA		Human	PMID:18688255
Biological Process	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage	Cpsf3	IDA		Mouse	MGI:MGI:4418605|PMID:18955505
Biological Process	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle	CPSF3	IMP		Human	PMID:30507380
Biological Process	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic	Cpsf3	IDA		Mouse	MGI:MGI:4418605|PMID:18955505

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern