Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CPSF6
  • Mouse genes Cpsf6
  • Rat genes Cpsf6
  • Zfish genes cpsf6
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cpsf6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:1990448	exon-exon junction complex binding	CPSF6	IDA		Human	PMID:19864460
Molecular Function	GO:0003729	mRNA binding	CPSF6	IDA		Human	PMID:21295486
Molecular Function	GO:0005515	protein binding	CPSF6	IPI	UniProtKB:O43809	Human	PMID:14561889
Molecular Function	GO:0005515	protein binding	CPSF6	IPI	UniProtKB:P08621	Human	PMID:14561889
Molecular Function	GO:0005515	protein binding	CPSF6	IPI	UniProtKB:P62995	Human	PMID:15169763
Molecular Function	GO:0005515	protein binding	CPSF6	IPI	UniProtKB:P84103	Human	PMID:15169763
Molecular Function	GO:0005515	protein binding	CPSF6	IPI	UniProtKB:Q16629	Human	PMID:15169763
Molecular Function	GO:0005515	protein binding	CPSF6	IPI	UniProtKB:O15162	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	CPSF6	IPI	UniProtKB:O43809	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	CPSF6	IPI	UniProtKB:Q9H0M0	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	CPSF6	IPI	UniProtKB:Q9H6L4	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	CPSF6	IPI	UniProtKB:Q9H0M0	Human	PMID:19447967
Molecular Function	GO:0005515	protein binding	CPSF6	IPI	UniProtKB:O43809	Human	PMID:19864460
Molecular Function	GO:0005515	protein binding	CPSF6	IPI	UniProtKB:Q92900	Human	PMID:19864460
Molecular Function	GO:0005515	protein binding	CPSF6	IPI	UniProtKB:Q9UBU9	Human	PMID:19864460
Molecular Function	GO:0005515	protein binding	CPSF6	IPI	UniProtKB:O43809	Human	PMID:21295486
Molecular Function	GO:0005515	protein binding	CPSF6	IPI	UniProtKB:O43809	Human	PMID:22960638
Molecular Function	GO:0005515	protein binding	CPSF6	IPI	UniProtKB:Q6FIE9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CPSF6	IPI	UniProtKB:Q96DC9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CPSF6	IPI	UniProtKB:Q9H6L4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CPSF6	IPI	UniProtKB:Q9Y3C6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CPSF6	IPI	UniProtKB:O43809	Human	PMID:29276085
Molecular Function	GO:0005515	protein binding	CPSF6	IPI	UniProtKB:Q6UN15	Human	PMID:29276085
Molecular Function	GO:0005515	protein binding	CPSF6	IPI	UniProtKB:Q69YN4	Human	PMID:29507755
Molecular Function	GO:0005515	protein binding	CPSF6	IPI	UniProtKB:Q9Y5L0	Human	PMID:30916345
Molecular Function	GO:0005515	protein binding	CPSF6	IPI	UniProtKB:Q9Y5L0	Human	PMID:31465518
Molecular Function	GO:0005515	protein binding	CPSF6	IPI	UniProtKB:O43809	Human	PMID:35177536
Molecular Function	GO:0005515	protein binding	Cpsf6	IPI	UniProtKB:E9Q5K9	Mouse	MGI:MGI:6161521|PMID:29799838
Molecular Function	GO:0043023	ribosomal large subunit binding	CPSF6	IDA		Human	PMID:19864460
Molecular Function	GO:0003723	RNA binding	CPSF6	IDA		Human	PMID:15169763
Molecular Function	GO:0003723	RNA binding	CPSF6	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	CPSF6	HDA		Human	PMID:22681889
Cellular Component	GO:0005737	cytoplasm	CPSF6	IDA		Human	PMID:19864460
Cellular Component	GO:0005737	cytoplasm	CPSF6	IDA		Human	PMID:30916345
Cellular Component	GO:0035061	interchromatin granule	CPSF6	IDA		Human	PMID:17267687
Cellular Component	GO:0016020	membrane	CPSF6	HDA		Human	PMID:19946888
Cellular Component	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex	CPSF6	IDA		Human	PMID:23187700
Cellular Component	GO:0005849	mRNA cleavage factor complex	CPSF6	IPI		Human	PMID:21295486
Cellular Component	GO:0005849	mRNA cleavage factor complex	CPSF6	IDA		Human	PMID:20695905
Cellular Component	GO:0005849	mRNA cleavage factor complex	CPSF6	IDA		Human	PMID:29276085
Cellular Component	GO:0005849	mRNA cleavage factor complex	CPSF6	IDA		Human	PMID:9659921
Cellular Component	GO:0016607	nuclear speck	CPSF6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016607	nuclear speck	CPSF6	IDA		Human	PMID:17267687
Cellular Component	GO:0005654	nucleoplasm	CPSF6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	CPSF6	IDA		Human	PMID:17267687
Cellular Component	GO:0005634	nucleus	CPSF6	IDA		Human	PMID:19864460
Cellular Component	GO:0005634	nucleus	CPSF6	IDA		Human	PMID:20695905
Cellular Component	GO:0005634	nucleus	CPSF6	IDA		Human	PMID:30916345
Cellular Component	GO:0005634	nucleus	Cpsf6	IDA		Mouse	MGI:MGI:3793872|PMID:18032416
Cellular Component	GO:0042382	paraspeckles	CPSF6	IDA		Human	PMID:17267687
Cellular Component	GO:0042382	paraspeckles	CPSF6	IDA		Human	PMID:9659921
Cellular Component	GO:0042382	paraspeckles	cpsf6	IDA		Zfish	PMID:32330562
Cellular Component	GO:0005726	perichromatin fibrils	CPSF6	IDA		Human	PMID:17267687
Cellular Component	GO:1990904	ribonucleoprotein complex	CPSF6	IDA		Human	PMID:18809582
Biological Process	GO:0051179	localization	CPSF6	IDA		Human	PMID:30916345
Biological Process	GO:1990120	messenger ribonucleoprotein complex assembly	CPSF6	IDA		Human	PMID:29276085
Biological Process	GO:0031124	mRNA 3'-end processing	CPSF6	IDA		Human	PMID:20695905
Biological Process	GO:0110104	mRNA alternative polyadenylation	CPSF6	IMP		Human	PMID:20695905
Biological Process	GO:0110104	mRNA alternative polyadenylation	CPSF6	IMP		Human	PMID:23187700
Biological Process	GO:0110104	mRNA alternative polyadenylation	CPSF6	IMP		Human	PMID:29276085
Biological Process	GO:0006397	mRNA processing	CPSF6	IDA		Human	PMID:14690600
Biological Process	GO:0046833	positive regulation of RNA export from nucleus	CPSF6	IMP		Human	PMID:19864460
Biological Process	GO:0098789	pre-mRNA cleavage required for polyadenylation	CPSF6	IDA		Human	PMID:20695905
Biological Process	GO:0098789	pre-mRNA cleavage required for polyadenylation	CPSF6	IMP		Human	PMID:20695905
Biological Process	GO:0051290	protein heterotetramerization	CPSF6	IDA		Human	PMID:23187700
Biological Process	GO:0051262	protein tetramerization	CPSF6	IDA		Human	PMID:20695905

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern