Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CRADD
  • Mouse genes Cradd
  • Rat genes Cradd
  • Zfish genes cradd
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cradd

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070513	death domain binding	CRADD	IPI	UniProtKB:Q13546	Human	PMID:9044836
Molecular Function	GO:0002020	protease binding	CRADD	IPI	UniProtKB:P42575	Human	PMID:9044836
Molecular Function	GO:0005515	protein binding	CRADD	IPI	UniProtKB:P42575	Human	PMID:11156409
Molecular Function	GO:0005515	protein binding	CRADD	IPI	UniProtKB:P42575	Human	PMID:15073321
Molecular Function	GO:0005515	protein binding	CRADD	IPI	UniProtKB:Q9HB75	Human	PMID:15073321
Molecular Function	GO:0005515	protein binding	CRADD	IPI	UniProtKB:P42575	Human	PMID:16652156
Molecular Function	GO:0005515	protein binding	CRADD	IPI	UniProtKB:Q9HB75	Human	PMID:16652156
Molecular Function	GO:0005515	protein binding	CRADD	IPI	UniProtKB:Q9HB75	Human	PMID:17159900
Molecular Function	GO:0005515	protein binding	CRADD	IPI	UniProtKB:P14079	Human	PMID:22458338
Molecular Function	GO:0005515	protein binding	CRADD	IPI	UniProtKB:P42575	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CRADD	IPI	UniProtKB:Q7L273	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CRADD	IPI	UniProtKB:Q8N3I7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CRADD	IPI	UniProtKB:Q8NEU8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CRADD	IPI	UniProtKB:Q9BYV2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CRADD	IPI	UniProtKB:P35609	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	CRADD	IPI	UniProtKB:P42575	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	CRADD	IPI	UniProtKB:Q9HB75	Human	PMID:27773430
Molecular Function	GO:0005515	protein binding	CRADD	IPI	UniProtKB:P42575	Human	PMID:31467278
Molecular Function	GO:0005515	protein binding	CRADD	IPI	UniProtKB:P42575	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CRADD	IPI	UniProtKB:Q8NEU8	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CRADD	IPI	UniProtKB:P42575	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRADD	IPI	UniProtKB:P19438	Human	PMID:8985253
Molecular Function	GO:0005515	protein binding	CRADD	IPI	UniProtKB:P42575	Human	PMID:8985253
Molecular Function	GO:0005515	protein binding	CRADD	IPI	UniProtKB:Q15628	Human	PMID:8985253
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	CRADD	IPI	UniProtKB:P42575	Human	PMID:9044836
Cellular Component	GO:0005737	cytoplasm	Cradd	IDA		Mouse	MGI:MGI:5426129|PMID:22279524
Cellular Component	GO:1905369	endopeptidase complex	CRADD	IPI		Human	PMID:15073321
Cellular Component	GO:0005634	nucleus	Cradd	IDA		Mouse	MGI:MGI:5426129|PMID:22279524
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	Cradd	IGI	MGI:MGI:1889507	Mouse	PMID:16183742
Biological Process	GO:0097190	apoptotic signaling pathway	CRADD	IMP		Human	PMID:8985253
Biological Process	GO:0071260	cellular response to mechanical stimulus	CRADD	IEP		Human	PMID:19593445
Biological Process	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	CRADD	IMP		Human	PMID:21726810
Biological Process	GO:0043065	positive regulation of apoptotic process	CRADD	IDA		Human	PMID:11821383
Biological Process	GO:2001235	positive regulation of apoptotic signaling pathway	Cradd	IGI	MGI:MGI:1889507	Mouse	PMID:16183742

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern