Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CRB1
  • Mouse genes Crb1
  • Rat genes Crb1
  • Zfish genes crb1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Crb1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	CRB1	IPI	UniProtKB:Q8N3R9	Human	PMID:11927608
Molecular Function	GO:0005515	protein binding	CRB1	IPI	UniProtKB:Q8NI35	Human	PMID:11927608
Molecular Function	GO:0005515	protein binding	CRB1	IPI	UniProtKB:A0A3Q1LY00	Human	PMID:15914641
Molecular Function	GO:0005515	protein binding	CRB1	IPI	UniProtKB:Q8N3R9	Human	PMID:15914641
Molecular Function	GO:0005515	protein binding	CRB1	IPI	UniProtKB:Q96JB8	Human	PMID:15914641
Molecular Function	GO:0005515	protein binding	CRB1	IPI	UniProtKB:A0A3Q1LY00	Human	PMID:17920587
Molecular Function	GO:0005515	protein binding	CRB1	IPI	UniProtKB:Q58CU2	Human	PMID:17920587
Molecular Function	GO:0005515	protein binding	CRB1	IPI	UniProtKB:Q8N3R9	Human	PMID:17920587
Molecular Function	GO:0005515	protein binding	CRB1	IPI	UniProtKB:Q8N3R9|UniProtKB:Q9HCM4	Human	PMID:17920587
Molecular Function	GO:0005515	protein binding	CRB1	IPI	UniProtKB:Q9HCM4	Human	PMID:17920587
Molecular Function	GO:0005515	protein binding	CRB1	IPI	UniProtKB:Q8N3R9	Human	PMID:33758649
Molecular Function	GO:0005515	protein binding	Crb1	IPI	PR:Q8VBX6	Mouse	PMID:15316081
Cellular Component	GO:0005912	adherens junction	CRB1	IDA		Human	PMID:15914641
Cellular Component	GO:0005912	adherens junction	Crb1	IDA		Mouse	PMID:15316081
Cellular Component	GO:0043296	apical junction complex	Crb1	IDA		Mouse	PMID:15316081
Cellular Component	GO:0045177	apical part of cell	Crb1	IDA		Mouse	PMID:25636444
Cellular Component	GO:0005911	cell-cell junction	Crb1	IDA		Mouse	PMID:17234588
Cellular Component	GO:0097386	glial cell projection	Crb1	IDA		Mouse	PMID:129154
Cellular Component	GO:0097386	glial cell projection	Crb1	IDA		Mouse	PMID:16885194
Cellular Component	GO:0005902	microvillus	Crb1	IDA		Mouse	PMID:16885194
Cellular Component	GO:0005902	microvillus	Crb1	IDA		Rat	PMID:25878282|RGD:13451131
Cellular Component	GO:0001917	photoreceptor inner segment	Crb1	IDA		Rat	PMID:25878282|RGD:13451131
Cellular Component	GO:0001750	photoreceptor outer segment	Crb1	IDA		Mouse	PMID:15316081
Cellular Component	GO:0005886	plasma membrane	Crb1	IDA		Mouse	PMID:16885194
Cellular Component	GO:0032991	protein-containing complex	CRB1	IDA		Human	PMID:15914641
Cellular Component	GO:0032991	protein-containing complex	crb1	IPI	ZFIN:ZDB-GENE-030616-450	Zfish	PMID:21262462
Cellular Component	GO:0035003	subapical complex	Crb1	IDA		Mouse	PMID:17234588
Biological Process	GO:0001974	blood vessel remodeling	Crb1	IMP		Mouse	PMID:25147295
Biological Process	GO:0048858	cell projection morphogenesis	crb1	IMP	ZFIN:ZDB-GENO-200320-1	Zfish	PMID:31002663
Biological Process	GO:0071482	cellular response to light stimulus	Crb1	IMP		Mouse	PMID:17234588
Biological Process	GO:0050908	detection of light stimulus involved in visual perception	Crb1	IMP		Mouse	PMID:22447858
Biological Process	GO:0061159	establishment of bipolar cell polarity involved in cell morphogenesis	Crb1	IMP		Mouse	PMID:15316081
Biological Process	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	crb1	IGI	ZFIN:ZDB-MRPHLNO-060612-1,ZFIN:ZDB-MRPHLNO-060822-1,ZFIN:ZDB-MRPHLNO-140206-1,ZFIN:ZDB-MRPHLNO-140206-2	Zfish	PMID:24071007
Biological Process	GO:0042462	eye photoreceptor cell development	Crb1	IMP	MGI:MGI:2676366	Mouse	PMID:12915475
Biological Process	GO:0042462	eye photoreceptor cell development	Crb1	IMP		Mouse	PMID:21052544
Biological Process	GO:0010467	gene expression	Crb1	IMP		Mouse	PMID:17234588
Biological Process	GO:0010001	glial cell differentiation	Crb1	IMP		Mouse	PMID:25147295
Biological Process	GO:0061024	membrane organization	Crb1	IMP		Mouse	PMID:12915475
Biological Process	GO:0061024	membrane organization	Crb1	IMP	MGI:MGI:2676366	Mouse	PMID:12915475
Biological Process	GO:0045494	photoreceptor cell maintenance	Crb1	IMP		Mouse	PMID:17234588
Biological Process	GO:0045494	photoreceptor cell maintenance	Crb1	IMP		Mouse	PMID:25147295
Biological Process	GO:0035845	photoreceptor cell outer segment organization	Crb1	IMP		Mouse	PMID:12915475
Biological Process	GO:0007009	plasma membrane organization	Crb1	IMP	MGI:MGI:3052072	Mouse	PMID:15316081
Biological Process	GO:0060060	post-embryonic retina morphogenesis in camera-type eye	Crb1	IMP		Mouse	PMID:12915475
Biological Process	GO:0060060	post-embryonic retina morphogenesis in camera-type eye	Crb1	IMP		Mouse	PMID:15316081
Biological Process	GO:0060060	post-embryonic retina morphogenesis in camera-type eye	Crb1	IMP		Mouse	PMID:16885194
Biological Process	GO:0008104	protein localization	Crb1	IMP		Mouse	PMID:16885194
Biological Process	GO:0060041	retina development in camera-type eye	Crb1	IMP		Mouse	PMID:22447858
Biological Process	GO:0060041	retina development in camera-type eye	Crb1	IMP		Mouse	PMID:25147295
Biological Process	GO:0010842	retina layer formation	Crb1	IMP		Mouse	PMID:17234588
Biological Process	GO:0060042	retina morphogenesis in camera-type eye	Crb1	IMP		Mouse	PMID:12915475
Biological Process	GO:0060042	retina morphogenesis in camera-type eye	Crb1	IMP		Mouse	PMID:17234588
Biological Process	GO:0060042	retina morphogenesis in camera-type eye	Crb1	IMP		Mouse	PMID:25147295
Biological Process	GO:0007601	visual perception	Crb1	IMP		Mouse	PMID:12915475
Biological Process	GO:0007601	visual perception	Crb1	IMP		Mouse	PMID:15316081

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern