Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CREB1
  • Mouse genes Creb1
  • Rat genes Creb1
  • Zfish genes creb1a,creb1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Creb1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:1990763	arrestin family protein binding	Creb1	IPI	RGD:2156	Rat	PMID:21223624|RGD:10059408
Molecular Function	GO:0035497	cAMP response element binding	CREB1	IDA		Human	PMID:19861239
Molecular Function	GO:0035497	cAMP response element binding	Creb1	IDA		Mouse	MGI:MGI:6414696|PMID:23729669
Molecular Function	GO:0003677	DNA binding	Creb1	IDA		Mouse	PMID:14594818
Molecular Function	GO:0003677	DNA binding	Creb1	IDA		Mouse	PMID:11354513
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	CREB1	IDA		Human	PMID:19861239
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Creb1	IMP		Mouse	MGI:MGI:4837978|PMID:20876357
Molecular Function	GO:0003700	DNA-binding transcription factor activity	CREB1	IDA		Human	PMID:8798441
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Creb1	IDA		Mouse	PMID:12220541
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Creb1	IMP		Rat	PMID:12697699|RGD:1624302
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	CREB1	IDA		Human	PMID:19861239
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Creb1	IDA		Rat	PMID:12409294|RGD:633667
Molecular Function	GO:0003690	double-stranded DNA binding	Creb1	IDA		Rat	PMID:12697699|RGD:1624302
Molecular Function	GO:0019899	enzyme binding	CREB1	IPI	UniProtKB:Q96EB6	Human	PMID:23382074
Molecular Function	GO:0035035	histone acetyltransferase binding	Creb1	IPI	RGD:620036	Rat	PMID:22357921|RGD:7257571
Molecular Function	GO:0030544	Hsp70 protein binding	Creb1	IPI	RGD:1311806	Rat	PMID:16207717|RGD:10059428
Molecular Function	GO:0042802	identical protein binding	CREB1	IPI	UniProtKB:P16220	Human	PMID:20102225
Molecular Function	GO:0042802	identical protein binding	CREB1	IPI	UniProtKB:P16220	Human	PMID:23661758
Molecular Function	GO:0042802	identical protein binding	CREB1	IPI	UniProtKB:P16220	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	CREB1	IPI	UniProtKB:P03259-2	Human	PMID:10722738
Molecular Function	GO:0005515	protein binding	CREB1	IPI	UniProtKB:Q6UUV9	Human	PMID:14506290
Molecular Function	GO:0005515	protein binding	CREB1	IPI	UniProtKB:Q6SA08	Human	PMID:15964553
Molecular Function	GO:0005515	protein binding	CREB1	IPI	UniProtKB:P49407	Human	PMID:16325578
Molecular Function	GO:0005515	protein binding	CREB1	IPI	UniProtKB:Q92793	Human	PMID:16799563
Molecular Function	GO:0005515	protein binding	CREB1	IPI	UniProtKB:P12980	Human	PMID:18160048
Molecular Function	GO:0005515	protein binding	CREB1	IPI	UniProtKB:Q86UE4	Human	PMID:18316612
Molecular Function	GO:0005515	protein binding	CREB1	IPI	UniProtKB:P0C746	Human	PMID:20102225
Molecular Function	GO:0005515	protein binding	CREB1	IPI	UniProtKB:P18846	Human	PMID:20102225
Molecular Function	GO:0005515	protein binding	CREB1	IPI	UniProtKB:Q16649	Human	PMID:20102225
Molecular Function	GO:0005515	protein binding	CREB1	IPI	UniProtKB:Q9DGW5	Human	PMID:20102225
Molecular Function	GO:0005515	protein binding	CREB1	IPI	UniProtKB:O00470	Human	PMID:20159610
Molecular Function	GO:0005515	protein binding	CREB1	IPI	UniProtKB:O00470	Human	PMID:20541704
Molecular Function	GO:0005515	protein binding	CREB1	IPI	UniProtKB:Q92793	Human	PMID:20541704
Molecular Function	GO:0005515	protein binding	CREB1	IPI	UniProtKB:Q6UUV9	Human	PMID:20936779
Molecular Function	GO:0005515	protein binding	CREB1	IPI	UniProtKB:O15405	Human	PMID:21172805
Molecular Function	GO:0005515	protein binding	CREB1	IPI	UniProtKB:Q96RG2	Human	PMID:21418524
Molecular Function	GO:0005515	protein binding	CREB1	IPI	UniProtKB:Q6SA08	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	CREB1	IPI	UniProtKB:O95644	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	CREB1	IPI	UniProtKB:P18846	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	CREB1	IPI	UniProtKB:Q13469	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	CREB1	IPI	UniProtKB:Q16649	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	CREB1	IPI	UniProtKB:O75928-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CREB1	IPI	UniProtKB:O95994	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CREB1	IPI	UniProtKB:P78317	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CREB1	IPI	UniProtKB:Q53ET0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CREB1	IPI	UniProtKB:Q6UUV9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CREB1	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Creb1	IPI	UniProtKB:Q60974	Mouse	MGI:MGI:5553029|PMID:24315104
Molecular Function	GO:0005515	protein binding	Creb1	IPI	UniProtKB:Q32M00	Mouse	MGI:MGI:5306541|PMID:21728997
Molecular Function	GO:0005515	protein binding	Creb1	IPI	PR:Q9Z2D6	Mouse	PMID:18511691
Molecular Function	GO:0005515	protein binding	Creb1	IPI	PR:Q810B3	Mouse	PMID:17550780
Molecular Function	GO:0005515	protein binding	Creb1	IPI	PR:P45481	Mouse	PMID:21072211
Molecular Function	GO:0005515	protein binding	Creb1	IPI	UniProtKB:B7SBD2	Rat	PMID:19196971|RGD:8554462
Molecular Function	GO:0005515	protein binding	Creb1	IPI	RGD:1307843	Rat	PMID:25031400|RGD:10059390
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	CREB1	IDA		Human	PMID:19861239
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	CREB1	IDA		Human	PMID:9065434
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Creb1	IDA		Mouse	PMID:28763438
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	CREB1	IPI	UniProtKB:P15336	Human	PMID:19861239
Molecular Function	GO:0043565	sequence-specific DNA binding	Creb1	IDA		Mouse	PMID:15030764
Molecular Function	GO:0043565	sequence-specific DNA binding	Creb1	IDA		Rat	PMID:12697699|RGD:1624302
Molecular Function	GO:0043565	sequence-specific DNA binding	Creb1	IDA		Rat	PMID:15632413|RGD:1643534
Molecular Function	GO:0043565	sequence-specific DNA binding	Creb1	IDA		Rat	PMID:16891311|RGD:1625706
Molecular Function	GO:0043565	sequence-specific DNA binding	Creb1	IDA		Rat	PMID:16959941|RGD:1599906
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	CREB1	IDA		Human	PMID:28473536
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Creb1	IMP		Rat	PMID:16382163|RGD:10059371
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Creb1	IDA		Rat	PMID:21367864|RGD:7247438
Molecular Function	GO:0001223	transcription coactivator binding	Creb1	IPI	UniProtKB:P45481	Rat	PMID:9413984|RGD:12793055
Cellular Component	GO:1990589	ATF4-CREB1 transcription factor complex	CREB1	IDA		Human	PMID:12871976
Cellular Component	GO:1990589	ATF4-CREB1 transcription factor complex	Creb1	IDA		Mouse	MGI:MGI:5613480|PMID:12871976
Cellular Component	GO:0030424	axon	Creb1	IDA		Rat	PMID:18193038|RGD:10059421
Cellular Component	GO:0000785	chromatin	Creb1	IDA		Mouse	MGI:MGI:6414696|PMID:23729669
Cellular Component	GO:0000785	chromatin	Creb1	IDA		Mouse	MGI:MGI:4839449|PMID:16427017
Cellular Component	GO:0000785	chromatin	Creb1	IMP		Mouse	MGI:MGI:4837978|PMID:20876357
Cellular Component	GO:0000785	chromatin	Creb1	IDA		Rat	PMID:15632413|RGD:1643534
Cellular Component	GO:0000785	chromatin	Creb1	IDA		Rat	PMID:16427017|RGD:8554469
Cellular Component	GO:0000791	euchromatin	CREB1	IDA		Human	PMID:19861239
Cellular Component	GO:0005759	mitochondrial matrix	Creb1	IDA		Rat	PMID:16207717|RGD:10059428
Cellular Component	GO:0005739	mitochondrion	Creb1	IDA		Rat	PMID:15663486|RGD:1358679
Cellular Component	GO:0005654	nucleoplasm	CREB1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	CREB1	IDA		Human	PMID:8798441
Cellular Component	GO:0005634	nucleus	Creb1	IDA		Mouse	MGI:MGI:5306541|PMID:21728997
Cellular Component	GO:0005634	nucleus	Creb1	IDA		Mouse	PMID:16251435
Cellular Component	GO:0005634	nucleus	Creb1	IDA		Mouse	PMID:21408140
Cellular Component	GO:0005634	nucleus	Creb1	IDA		Mouse	PMID:14517290
Cellular Component	GO:0005634	nucleus	Creb1	IDA		Mouse	PMID:15927180
Cellular Component	GO:0005634	nucleus	Creb1	IDA		Mouse	PMID:15817708
Cellular Component	GO:0005634	nucleus	Creb1	IDA		Mouse	PMID:7565774
Cellular Component	GO:0005634	nucleus	Creb1	IDA		Rat	PMID:12697699|RGD:1624302
Cellular Component	GO:0005634	nucleus	Creb1	IDA		Rat	PMID:15632413|RGD:1643534
Cellular Component	GO:0005634	nucleus	Creb1	IDA		Rat	PMID:16959941|RGD:1599906
Cellular Component	GO:0005634	nucleus	Creb1	IDA		Rat	PMID:19033670|RGD:8554824
Cellular Component	GO:0005634	nucleus	Creb1	IDA		Rat	PMID:21367864|RGD:7247438
Cellular Component	GO:0005634	nucleus	Creb1	IDA		Rat	PMID:25031400|RGD:10059390
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	CREB1	IPI		Human	PMID:20102225
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	Creb1	IPI		Mouse	MGI:MGI:5613480|PMID:12871976
Cellular Component	GO:0005667	transcription regulator complex	Creb1	IDA		Mouse	PMID:11354513
Cellular Component	GO:0005667	transcription regulator complex	Creb1	IDA		Rat	PMID:15632413|RGD:1643534
Biological Process	GO:0007568	aging	Creb1	IEP		Rat	PMID:14670355|RGD:10059396
Biological Process	GO:0007409	axonogenesis	Creb1	IMP	MGI:MGI:2153538	Mouse	PMID:11988169
Biological Process	GO:0019933	cAMP-mediated signaling	CREB1	IDA		Human	PMID:25644539
Biological Process	GO:0071398	cellular response to fatty acid	Creb1	IEP		Rat	PMID:16382163|RGD:10059371
Biological Process	GO:1904322	cellular response to forskolin	CREB1	IDA		Human	PMID:25644539
Biological Process	GO:0071363	cellular response to growth factor stimulus	Creb1	IDA		Mouse	MGI:MGI:4839449|PMID:16427017
Biological Process	GO:0035729	cellular response to hepatocyte growth factor stimulus	Creb1	IDA		Mouse	PMID:21072211
Biological Process	GO:1990314	cellular response to insulin-like growth factor stimulus	Creb1	IEP		Rat	PMID:23865718|RGD:10059387
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	Creb1	IEP		Mouse	PMID:20439489
Biological Process	GO:1990090	cellular response to nerve growth factor stimulus	Creb1	IEP		Rat	PMID:18193038|RGD:10059421
Biological Process	GO:0036120	cellular response to platelet-derived growth factor stimulus	Creb1	IEP		Rat	PMID:21505978|RGD:10059431
Biological Process	GO:0071300	cellular response to retinoic acid	Creb1	IMP		Mouse	MGI:MGI:4837978|PMID:20876357
Biological Process	GO:0071560	cellular response to transforming growth factor beta stimulus	Creb1	IEP		Rat	PMID:21308733|RGD:10059386
Biological Process	GO:0071294	cellular response to zinc ion	Creb1	IDA		Mouse	PMID:23716681
Biological Process	GO:0034670	chemotaxis to arachidonic acid	Creb1	IMP		Rat	PMID:16382163|RGD:10059371
Biological Process	GO:0007623	circadian rhythm	Creb1	IDA		Mouse	MGI:MGI:5567906|PMID:20852621
Biological Process	GO:0007623	circadian rhythm	Creb1	IEP		Rat	PMID:21367864|RGD:7247438
Biological Process	GO:0060028	convergent extension involved in axis elongation	creb1a	IMP		Zfish	PMID:17531969
Biological Process	GO:0046879	hormone secretion	Creb1	IMP	MGI:MGI:2176173,MGI:MGI:2181395	Mouse	PMID:16141355
Biological Process	GO:0007595	lactation	Creb1	IMP	MGI:MGI:2176173,MGI:MGI:2181395	Mouse	PMID:16141355
Biological Process	GO:0060428	lung epithelium development	Creb1	IMP	MGI:MGI:4999627	Mouse	PMID:21408140
Biological Process	GO:0060430	lung saccule development	Creb1	IMP	MGI:MGI:4999627	Mouse	PMID:21408140
Biological Process	GO:0030879	mammary gland development	Creb1	IMP	MGI:MGI:2176173,MGI:MGI:2181395	Mouse	PMID:16141355
Biological Process	GO:0007613	memory	Creb1	IMP		Mouse	PMID:23223304
Biological Process	GO:0007613	memory	Creb1	IMP		Rat	PMID:16687181|RGD:1582430
Biological Process	GO:0030917	midbrain-hindbrain boundary development	creb1a	IMP		Zfish	PMID:17531969
Biological Process	GO:0042789	mRNA transcription by RNA polymerase II	CREB1	IDA		Human	PMID:25644539
Biological Process	GO:0010629	negative regulation of gene expression	Creb1	IMP		Rat	PMID:21816899|RGD:10059418
Biological Process	GO:1901215	negative regulation of neuron death	Creb1	IMP		Rat	PMID:18193038|RGD:10059421
Biological Process	GO:0010944	negative regulation of transcription by competitive promoter binding	CREB1	IDA		Human	PMID:19861239
Biological Process	GO:0030316	osteoclast differentiation	Creb1	IDA		Mouse	PMID:23395171
Biological Process	GO:0021983	pituitary gland development	Creb1	IMP	MGI:MGI:2176173,MGI:MGI:2181395	Mouse	PMID:16141355
Biological Process	GO:0043065	positive regulation of apoptotic process	Creb1	IMP		Rat	PMID:24189100|RGD:10059384
Biological Process	GO:0055025	positive regulation of cardiac muscle tissue development	Creb1	IMP		Mouse	PMID:24364879
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Creb1	IGI	UniProtKB:Q32M00	Mouse	MGI:MGI:5306541|PMID:21728997
Biological Process	GO:0045600	positive regulation of fat cell differentiation	Creb1	IGI	UniProtKB:Q32M00	Mouse	MGI:MGI:5306541|PMID:21728997
Biological Process	GO:0046887	positive regulation of hormone secretion	Creb1	IMP	MGI:MGI:2176173,MGI:MGI:2181395	Mouse	PMID:16141355
Biological Process	GO:0046889	positive regulation of lipid biosynthetic process	Creb1	IGI	UniProtKB:Q32M00	Mouse	MGI:MGI:5306541|PMID:21728997
Biological Process	GO:1900273	positive regulation of long-term synaptic potentiation	Creb1	IMP		Rat	PMID:16000619|RGD:10059422
Biological Process	GO:0040018	positive regulation of multicellular organism growth	Creb1	IMP	MGI:MGI:2176173,MGI:MGI:2181395	Mouse	PMID:16141355
Biological Process	GO:0045672	positive regulation of osteoclast differentiation	Creb1	IDA		Mouse	PMID:23395171
Biological Process	GO:0045899	positive regulation of RNA polymerase II transcription preinitiation complex assembly	Creb1	IMP		Rat	PMID:16891311|RGD:1625706
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	CREB1	IDA		Human	PMID:8798441
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	CREB1	IDA		Human	PMID:1655749
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	CREB1	IDA		Human	PMID:19861239
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Creb1	IMP		Mouse	MGI:MGI:4837978|PMID:20876357
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Creb1	IDA		Mouse	MGI:MGI:5567906|PMID:20852621
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Creb1	IDA		Mouse	PMID:18252718
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Creb1	IDA		Rat	PMID:12409294|RGD:633667
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Creb1	IMP		Rat	PMID:16891311|RGD:1625706
Biological Process	GO:0032916	positive regulation of transforming growth factor beta3 production	Creb1	IMP		Rat	PMID:16891311|RGD:1625706
Biological Process	GO:0032916	positive regulation of transforming growth factor beta3 production	Creb1	IMP		Rat	PMID:21308733|RGD:10059386
Biological Process	GO:0006468	protein phosphorylation	CREB1	IDA		Human	PMID:8798441
Biological Process	GO:0050821	protein stabilization	Creb1	IMP		Mouse	MGI:MGI:5306541|PMID:21728997
Biological Process	GO:0042981	regulation of apoptotic process	Creb1	IDA		Rat	PMID:12939230|RGD:727769
Biological Process	GO:0008361	regulation of cell size	Creb1	IGI	MGI:MGI:1332637	Mouse	PMID:12015964
Biological Process	GO:0042752	regulation of circadian rhythm	Creb1	IMP		Rat	PMID:12409294|RGD:633667
Biological Process	GO:0006355	regulation of DNA-templated transcription	Creb1	IDA		Mouse	PMID:12220541
Biological Process	GO:0048145	regulation of fibroblast proliferation	Creb1	IMP		Rat	PMID:19285017|RGD:10059427
Biological Process	GO:0060251	regulation of glial cell proliferation	Creb1	IMP		Rat	PMID:19365572|RGD:10059410
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Creb1	IDA		Mouse	MGI:MGI:5613480|PMID:12871976
Biological Process	GO:0014823	response to activity	Creb1	IEP		Rat	PMID:25031400|RGD:10059390
Biological Process	GO:1903494	response to dehydroepiandrosterone	Creb1	IEP		Rat	PMID:22523357|RGD:155226858
Biological Process	GO:0036017	response to erythropoietin	Creb1	IDA		Rat	PMID:17368520|RGD:155226865
Biological Process	GO:0033762	response to glucagon	Creb1	IMP		Mouse	MGI:MGI:5567906|PMID:20852621
Biological Process	GO:1990910	response to hypobaric hypoxia	Creb1	IEP		Rat	PMID:22523357|RGD:155226858
Biological Process	GO:0001666	response to hypoxia	Creb1	IEP		Rat	PMID:24084215|RGD:10059409
Biological Process	GO:0010035	response to inorganic substance	Creb1	IMP		Mouse	PMID:25644539
Biological Process	GO:1902065	response to L-glutamate	Creb1	IEP		Rat	PMID:19365572|RGD:10059410
Biological Process	GO:0035094	response to nicotine	Creb1	IEP		Rat	PMID:22952905|RGD:10059420
Biological Process	GO:0010033	response to organic substance	CREB1	IDA		Human	PMID:8798441
Biological Process	GO:0014074	response to purine-containing compound	CREB1	IDA		Human	PMID:25644539
Biological Process	GO:0009410	response to xenobiotic stimulus	Creb1	IDA		Mouse	PMID:9098922
Biological Process	GO:0009410	response to xenobiotic stimulus	Creb1	IEP		Rat	PMID:21223624|RGD:10059408
Biological Process	GO:0033363	secretory granule organization	Creb1	IMP	MGI:MGI:4999627	Mouse	PMID:21408140
Biological Process	GO:0001756	somitogenesis	creb1a	IMP		Zfish	PMID:17531969
Biological Process	GO:0006366	transcription by RNA polymerase II	Creb1	IMP		Rat	PMID:12697699|RGD:1624302
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	Creb1	IMP		Rat	PMID:16891311|RGD:1625706
Biological Process	GO:0060509	type I pneumocyte differentiation	Creb1	IMP	MGI:MGI:4999627	Mouse	PMID:21408140
Biological Process	GO:0008542	visual learning	Creb1	IMP		Rat	PMID:25031400|RGD:10059390

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern