Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CREB3L3
  • Mouse genes Creb3l3
  • Rat genes Creb3l3
  • Zfish genes creb3l3a,creb3l3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Creb3l3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	CREB3L3	IDA		Human	PMID:11353085
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	CREB3L3	IMP		Human	PMID:11353085
Molecular Function	GO:0042802	identical protein binding	CREB3L3	IPI	UniProtKB:Q68CJ9	Human	PMID:20102225
Molecular Function	GO:0042802	identical protein binding	CREB3L3	IPI	UniProtKB:Q68CJ9	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	CREB3L3	IPI	UniProtKB:P18850	Human	PMID:16469704
Molecular Function	GO:0005515	protein binding	CREB3L3	IPI	UniProtKB:O43889	Human	PMID:20102225
Molecular Function	GO:0005515	protein binding	CREB3L3	IPI	UniProtKB:Q16649	Human	PMID:20102225
Molecular Function	GO:0005515	protein binding	CREB3L3	IPI	UniProtKB:O43889	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	CREB3L3	IPI	UniProtKB:Q96BA8	Human	PMID:23661758
Molecular Function	GO:0005515	protein binding	CREB3L3	IPI	UniProtKB:O00155	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CREB3L3	IPI	UniProtKB:O43765	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CREB3L3	IPI	UniProtKB:Q02094	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CREB3L3	IPI	UniProtKB:Q13190	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CREB3L3	IPI	UniProtKB:Q5J8X5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CREB3L3	IPI	UniProtKB:Q8N8B7-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CREB3L3	IPI	UniProtKB:Q8NBI2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CREB3L3	IPI	UniProtKB:Q8WW34-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CREB3L3	IPI	UniProtKB:Q969F0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CREB3L3	IPI	UniProtKB:Q96EC8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CREB3L3	IPI	UniProtKB:Q96EQ0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CREB3L3	IPI	UniProtKB:Q96EZ8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CREB3L3	IPI	UniProtKB:Q96GQ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CREB3L3	IPI	UniProtKB:Q96LK0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CREB3L3	IPI	UniProtKB:Q9C005	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CREB3L3	IPI	UniProtKB:Q9NUM3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CREB3L3	IPI	UniProtKB:Q9NVC3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CREB3L3	IPI	UniProtKB:Q9Y228	Human	PMID:32296183
Molecular Function	GO:0046982	protein heterodimerization activity	CREB3L3	IPI	UniProtKB:P18850	Human	PMID:16469704
Molecular Function	GO:0042803	protein homodimerization activity	CREB3L3	IDA		Human	PMID:16469704
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	CREB3L3	IDA		Human	PMID:11353085
Molecular Function	GO:0000976	transcription cis-regulatory region binding	CREB3L3	IDA		Human	PMID:16469704
Cellular Component	GO:0005783	endoplasmic reticulum	CREB3L3	IDA		Human	PMID:16236796
Cellular Component	GO:0005783	endoplasmic reticulum	CREB3L3	IDA		Human	PMID:16469704
Cellular Component	GO:0016020	membrane	Creb3l3	IDA		Mouse	MGI:MGI:5616319|PMID:16469704
Cellular Component	GO:0005634	nucleus	CREB3L3	IDA		Human	PMID:16469704
Cellular Component	GO:0005634	nucleus	Creb3l3	IDA		Mouse	MGI:MGI:5616319|PMID:16469704
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	CREB3L3	IMP		Human	PMID:11353085
Biological Process	GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	CREB3L3	IDA		Human	PMID:16469704
Biological Process	GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	Creb3l3	IMP		Mouse	MGI:MGI:5616319|PMID:16469704

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern