Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CREB3L4
  • Mouse genes Creb3l4
  • Rat genes Creb3l4
  • Zfish genes creb3l4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Creb3l4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Creb3l4	IDA		Mouse	PMID:11956138
Molecular Function	GO:0003677	DNA binding	Creb3l4	IDA		Mouse	PMID:15938716
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Creb3l4	IMP		Mouse	MGI:MGI:3611598|PMID:15938716
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Creb3l4	IDA		Mouse	MGI:MGI:3611598|PMID:15938716
Molecular Function	GO:0005515	protein binding	CREB3L4	IPI	UniProtKB:O43681	Human	PMID:32296183
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Creb3l4	IDA		Mouse	MGI:MGI:3611598|PMID:15938716
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	CREB3L4	IDA		Human	PMID:28473536
Cellular Component	GO:0005783	endoplasmic reticulum	CREB3L4	IDA		Human	PMID:16236796
Cellular Component	GO:0005794	Golgi apparatus	CREB3L4	IDA		Human	PMID:16236796
Cellular Component	GO:0005739	mitochondrion	CREB3L4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0031965	nuclear membrane	CREB3L4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	CREB3L4	IDA		Human	GO_REF:0000052
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	CREB3L4	IDA		Human	PMID:16236796
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Creb3l4	IMP		Mouse	MGI:MGI:3611598|PMID:15938716
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Creb3l4	IDA		Mouse	PMID:15938716
Biological Process	GO:0007283	spermatogenesis	Creb3l4	IMP	MGI:MGI:3589381	Mouse	PMID:16107712

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern