Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CREB5
  • Mouse genes Creb5
  • Rat genes Creb5
  • Zfish genes creb5a,creb5b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Creb5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Creb5	IDA		Mouse	PMID:19948881
Molecular Function	GO:0003700	DNA-binding transcription factor activity	CREB5	IDA		Human	PMID:8378084
Molecular Function	GO:0005515	protein binding	CREB5	IPI	UniProtKB:P05412	Human	PMID:8440710
Molecular Function	GO:0005515	protein binding	CREB5	IPI	UniProtKB:P15336	Human	PMID:8440710
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	CREB5	IDA		Human	PMID:28473536
Cellular Component	GO:0070062	extracellular exosome	CREB5	HDA		Human	PMID:19056867
Cellular Component	GO:0005634	nucleus	Creb5	IDA		Mouse	PMID:19948881
Biological Process	GO:0060612	adipose tissue development	Creb5	IGI	MGI:MGI:109349	Mouse	PMID:19948881
Biological Process	GO:0045444	fat cell differentiation	Creb5	IGI	MGI:MGI:109349	Mouse	PMID:19948881
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	CREB5	IDA		Human	PMID:8378084
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Creb5	IGI	MGI:MGI:109349	Mouse	PMID:19948881
Biological Process	GO:0050872	white fat cell differentiation	Creb5	IMP	MGI:MGI:4421136	Mouse	PMID:19948881
Biological Process	GO:0050872	white fat cell differentiation	Creb5	IGI	MGI:MGI:109349	Mouse	PMID:19948881

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern