Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CRHBP
  • Mouse genes Crhbp
  • Rat genes Crhbp
  • Zfish genes crhbp
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Crhbp

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051424	corticotropin-releasing hormone binding	CRHBP	IPI	UniProtKB:P06850	Human	PMID:18234674
Molecular Function	GO:0051424	corticotropin-releasing hormone binding	CRHBP	IDA		Human	PMID:1846945
Molecular Function	GO:0051424	corticotropin-releasing hormone binding	Crhbp	IPI	UniProtKB:P01142	Mouse	MGI:MGI:5315362|PMID:12895416
Molecular Function	GO:0051424	corticotropin-releasing hormone binding	Crhbp	IDA		Mouse	PMID:7556876
Molecular Function	GO:0051424	corticotropin-releasing hormone binding	Crhbp	IPI	RGD:620505	Rat	PMID:11572971|RGD:5508795
Molecular Function	GO:0051424	corticotropin-releasing hormone binding	Crhbp	IDA		Rat	PMID:1846945|RGD:69816
Molecular Function	GO:0042277	peptide binding	Crhbp	IDA		Rat	PMID:11572971|RGD:5508795
Molecular Function	GO:0042277	peptide binding	Crhbp	IPI	RGD:1614218	Rat	PMID:15223302|RGD:5508815
Molecular Function	GO:0042277	peptide binding	Crhbp	IPI	RGD:3929	Rat	PMID:15223302|RGD:5508815
Molecular Function	GO:0005515	protein binding	CRHBP	IPI	UniProtKB:P55089	Human	PMID:18234674
Cellular Component	GO:0043679	axon terminus	Crhbp	IDA		Rat	PMID:10524337|RGD:5490549
Cellular Component	GO:0030425	dendrite	Crhbp	IDA		Rat	PMID:10524337|RGD:5490549
Cellular Component	GO:0031045	dense core granule	Crhbp	IDA		Rat	PMID:10524337|RGD:5490549
Cellular Component	GO:0005615	extracellular space	CRHBP	IDA		Human	PMID:1846945
Cellular Component	GO:0005615	extracellular space	CRHBP	IDA		Human	PMID:18559919
Cellular Component	GO:0005615	extracellular space	Crhbp	IDA		Mouse	MGI:MGI:5315350|PMID:15976007
Cellular Component	GO:0005615	extracellular space	Crhbp	IDA		Rat	PMID:1846945|RGD:69816
Cellular Component	GO:0005874	microtubule	Crhbp	IDA		Rat	PMID:10524337|RGD:5490549
Cellular Component	GO:0005771	multivesicular body	Crhbp	IDA		Rat	PMID:10524337|RGD:5490549
Cellular Component	GO:0005634	nucleus	Crhbp	IDA		Mouse	MGI:MGI:5315350|PMID:15976007
Cellular Component	GO:0043204	perikaryon	Crhbp	IDA		Rat	PMID:10524337|RGD:5490549
Cellular Component	GO:0005767	secondary lysosome	Crhbp	IDA		Rat	PMID:10524337|RGD:5490549
Cellular Component	GO:0030141	secretory granule	CRHBP	IDA		Human	PMID:21624661
Cellular Component	GO:0043196	varicosity	Crhbp	IDA		Rat	PMID:10524337|RGD:5490549
Biological Process	GO:0048149	behavioral response to ethanol	CRHBP	IMP		Human	PMID:21039637
Biological Process	GO:0071277	cellular response to calcium ion	Crhbp	IDA		Mouse	MGI:MGI:5315350|PMID:15976007
Biological Process	GO:0071320	cellular response to cAMP	Crhbp	IDA		Mouse	MGI:MGI:5315350|PMID:15976007
Biological Process	GO:0071314	cellular response to cocaine	Crhbp	IDA		Rat	PMID:14751291|RGD:8553798
Biological Process	GO:0071392	cellular response to estradiol stimulus	CRHBP	IDA		Human	PMID:15345745
Biological Process	GO:0071392	cellular response to estradiol stimulus	Crhbp	IDA		Mouse	MGI:MGI:5315355|PMID:15345745
Biological Process	GO:0071392	cellular response to estradiol stimulus	Crhbp	IDA		Rat	PMID:15345745|RGD:8554074
Biological Process	GO:0071391	cellular response to estrogen stimulus	CRHBP	IDA		Human	PMID:15345745
Biological Process	GO:0071391	cellular response to estrogen stimulus	Crhbp	IDA		Rat	PMID:15345745|RGD:8554074
Biological Process	GO:0097211	cellular response to gonadotropin-releasing hormone	Crhbp	IDA		Mouse	MGI:MGI:5315350|PMID:15976007
Biological Process	GO:0035903	cellular response to immobilization stress	Crhbp	IDA		Rat	PMID:15530648|RGD:1358528
Biological Process	GO:0035865	cellular response to potassium ion	CRHBP	IDA		Human	PMID:21624661
Biological Process	GO:0071356	cellular response to tumor necrosis factor	CRHBP	IDA		Human	PMID:15345745
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	Crhbp	IDA		Mouse	MGI:MGI:5315350|PMID:15976007
Biological Process	GO:0007565	female pregnancy	CRHBP	IEP		Human	PMID:1846945
Biological Process	GO:0007565	female pregnancy	CRHBP	IDA		Human	PMID:18559919
Biological Process	GO:0042445	hormone metabolic process	Crhbp	IDA		Mouse	PMID:7556876
Biological Process	GO:0042445	hormone metabolic process	Crhbp	IEP		Rat	PMID:15530648|RGD:1358528
Biological Process	GO:0009755	hormone-mediated signaling pathway	CRHBP	IDA		Human	PMID:18234674
Biological Process	GO:0006954	inflammatory response	CRHBP	IDA		Human	PMID:18559919
Biological Process	GO:0002125	maternal aggressive behavior	Crhbp	IMP		Mouse	MGI:MGI:3831225|PMID:18929624
Biological Process	GO:0051460	negative regulation of corticotropin secretion	CRHBP	IDA		Human	PMID:1846945
Biological Process	GO:0051460	negative regulation of corticotropin secretion	Crhbp	IDA		Rat	PMID:1846945|RGD:69816
Biological Process	GO:1900011	negative regulation of corticotropin-releasing hormone receptor activity	CRHBP	IDA		Human	PMID:18234674
Biological Process	GO:0045055	regulated exocytosis	CRHBP	IDA		Human	PMID:21624661
Biological Process	GO:0080135	regulation of cellular response to stress	CRHBP	IMP		Human	PMID:21039637
Biological Process	GO:0051459	regulation of corticotropin secretion	CRHBP	IDA		Human	PMID:13150566
Biological Process	GO:2000310	regulation of NMDA receptor activity	Crhbp	IDA		Mouse	MGI:MGI:5315362|PMID:12895416
Biological Process	GO:0001963	synaptic transmission, dopaminergic	Crhbp	IDA		Mouse	MGI:MGI:5315362|PMID:12895416
Biological Process	GO:0001963	synaptic transmission, dopaminergic	Crhbp	IEP		Rat	PMID:18478589|RGD:8553722

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern