Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CRTC1
  • Mouse genes Crtc1
  • Rat genes Crtc1
  • Zfish genes crtc1a,crtc1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Crtc1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008140	cAMP response element binding protein binding	CRTC1	IDA		Human	PMID:14536081
Molecular Function	GO:0005515	protein binding	CRTC1	IPI	UniProtKB:P16220	Human	PMID:14506290
Molecular Function	GO:0005515	protein binding	CRTC1	IPI	UniProtKB:P16220	Human	PMID:20936779
Molecular Function	GO:0005515	protein binding	CRTC1	IPI	UniProtKB:P16220	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Crtc1	IPI	UniProtKB:P62258|UniProtKB:Q08209	Mouse	MGI:MGI:6282941|PMID:30611118
Cellular Component	GO:0005737	cytoplasm	Crtc1	IDA		Mouse	MGI:MGI:5532783|PMID:23993098
Cellular Component	GO:0005737	cytoplasm	Crtc1	IDA		Mouse	PMID:23223304
Cellular Component	GO:0005737	cytoplasm	Crtc1	IDA		Rat	PMID:21895802|RGD:9685161
Cellular Component	GO:0005829	cytosol	CRTC1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0030425	dendrite	Crtc1	IDA		Rat	PMID:22770221|RGD:9685164
Cellular Component	GO:0098978	glutamatergic synapse	Crtc1	EXP		Rat	PMID:22770221|RGD:9685164
Cellular Component	GO:0098978	glutamatergic synapse	Crtc1	IDA		Rat	PMID:22770221|RGD:9685164
Cellular Component	GO:0098978	glutamatergic synapse	Crtc1	IMP		Rat	PMID:22770221|RGD:9685164
Cellular Component	GO:0043025	neuronal cell body	Crtc1	IDA		Rat	PMID:22770221|RGD:9685164
Cellular Component	GO:0016604	nuclear body	CRTC1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	CRTC1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	CRTC1	IDA		Human	PMID:14506290
Cellular Component	GO:0005634	nucleus	Crtc1	IDA		Mouse	MGI:MGI:5532783|PMID:23993098
Cellular Component	GO:0005634	nucleus	Crtc1	IDA		Mouse	PMID:23223304
Cellular Component	GO:0005634	nucleus	Crtc1	IDA		Rat	PMID:21895802|RGD:9685161
Cellular Component	GO:0005886	plasma membrane	CRTC1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0014069	postsynaptic density	Crtc1	IDA		Rat	PMID:22770221|RGD:9685164
Cellular Component	GO:0045202	synapse	Crtc1	IDA		Rat	PMID:22770221|RGD:9685164
Biological Process	GO:0097009	energy homeostasis	Crtc1	IMP	MGI:MGI:3829386	Mouse	PMID:19734865
Biological Process	GO:0043153	entrainment of circadian clock by photoperiod	Crtc1	IMP		Mouse	MGI:MGI:5532783|PMID:23993098
Biological Process	GO:0007613	memory	Crtc1	IMP		Mouse	PMID:23223304
Biological Process	GO:0008152	metabolic process	Crtc1	IMP	MGI:MGI:3829386	Mouse	PMID:19734865
Biological Process	GO:1902631	negative regulation of membrane hyperpolarization	Crtc1	IDA		Mouse	PMID:23223304
Biological Process	GO:0032793	positive regulation of CREB transcription factor activity	Crtc1	IMP		Mouse	MGI:MGI:5532783|PMID:23993098
Biological Process	GO:1900006	positive regulation of dendrite development	Crtc1	IMP		Rat	PMID:21895802|RGD:9685161
Biological Process	GO:1900273	positive regulation of long-term synaptic potentiation	Crtc1	IMP		Rat	PMID:17183642|RGD:9685167
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	CRTC1	IDA		Human	PMID:14536081
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Crtc1	IDA		Mouse	PMID:23223304
Biological Process	GO:0099527	postsynapse to nucleus signaling pathway	Crtc1	EXP		Rat	PMID:22770221|RGD:9685164
Biological Process	GO:0099527	postsynapse to nucleus signaling pathway	Crtc1	IDA		Rat	PMID:22770221|RGD:9685164
Biological Process	GO:0099527	postsynapse to nucleus signaling pathway	Crtc1	IEP		Rat	PMID:22770221|RGD:9685164
Biological Process	GO:0099527	postsynapse to nucleus signaling pathway	Crtc1	IMP		Rat	PMID:22770221|RGD:9685164

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern