Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CRTC2
  • Mouse genes Crtc2
  • Rat genes Crtc2
  • Zfish genes crtc2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Crtc2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Crtc2	IDA		Rat	PMID:21826657|RGD:9685171
Molecular Function	GO:0005515	protein binding	CRTC2	IPI	UniProtKB:Q15233	Human	PMID:18077367
Molecular Function	GO:0005515	protein binding	CRTC2	IPI	UniProtKB:P03206	Human	PMID:19164291
Molecular Function	GO:0005515	protein binding	CRTC2	IPI	UniProtKB:P18850	Human	PMID:19543265
Molecular Function	GO:0005515	protein binding	CRTC2	IPI	UniProtKB:P16220	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRTC2	IPI	UniProtKB:Q2TAC2-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRTC2	IPI	UniProtKB:Q8N5M1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRTC2	IPI	UniProtKB:Q9UJX2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRTC2	IPI	UniProtKB:Q9UMX1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Crtc2	IPI	UniProtKB:P62258|UniProtKB:Q08209	Mouse	MGI:MGI:6282941|PMID:30611118
Molecular Function	GO:0005515	protein binding	Crtc2	IPI	UniProtKB:F6VAN0|UniProtKB:P18850	Mouse	MGI:MGI:3851621|PMID:19543265
Molecular Function	GO:0005515	protein binding	Crtc2	IPI	UniProtKB:Q9R1A8	Mouse	MGI:MGI:3761061|PMID:17805301
Molecular Function	GO:0005515	protein binding	Crtc2	IPI	UniProtKB:P29994-1|UniProtKB:P63328	Mouse	MGI:MGI:5319409|PMID:22495310
Molecular Function	GO:0005515	protein binding	Crtc2	IPI	PR:Q9JHD1	Mouse	PMID:24051374
Cellular Component	GO:0005737	cytoplasm	Crtc2	IDA		Mouse	MGI:MGI:3611510|PMID:16308421
Cellular Component	GO:0005737	cytoplasm	Crtc2	IDA		Mouse	MGI:MGI:3606826|PMID:16148943
Cellular Component	GO:0005737	cytoplasm	Crtc2	IDA		Mouse	PMID:24674967
Cellular Component	GO:0005737	cytoplasm	Crtc2	IDA		Mouse	PMID:24768298
Cellular Component	GO:0005737	cytoplasm	Crtc2	IDA		Mouse	PMID:16684769
Cellular Component	GO:0005737	cytoplasm	Crtc2	IDA		Rat	PMID:21826657|RGD:9685171
Cellular Component	GO:0070062	extracellular exosome	CRTC2	HDA		Human	PMID:19056867
Cellular Component	GO:0005654	nucleoplasm	CRTC2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Crtc2	IDA		Mouse	MGI:MGI:3611510|PMID:16308421
Cellular Component	GO:0005634	nucleus	Crtc2	IDA		Mouse	MGI:MGI:3606826|PMID:16148943
Cellular Component	GO:0005634	nucleus	Crtc2	IDA		Mouse	PMID:24674967
Cellular Component	GO:0005634	nucleus	Crtc2	IDA		Mouse	PMID:24768298
Cellular Component	GO:0005634	nucleus	Crtc2	IDA		Mouse	PMID:16684769
Cellular Component	GO:0005634	nucleus	Crtc2	IDA		Rat	PMID:21826657|RGD:9685171
Biological Process	GO:0006094	gluconeogenesis	Crtc2	IDA		Mouse	MGI:MGI:3606826|PMID:16148943
Biological Process	GO:0042593	glucose homeostasis	Crtc2	IMP		Mouse	MGI:MGI:3611510|PMID:16308421
Biological Process	GO:0042593	glucose homeostasis	Crtc2	IMP		Rat	PMID:19706791|RGD:9685172
Biological Process	GO:0043970	histone H3-K9 acetylation	Crtc2	IGI	MGI:MGI:1343094	Mouse	PMID:24051374
Biological Process	GO:0032793	positive regulation of CREB transcription factor activity	Crtc2	IDA		Mouse	MGI:MGI:3606826|PMID:16148943
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Crtc2	IGI	MGI:MGI:2155884	Mouse	PMID:24051374
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Crtc2	IGI	MGI:MGI:1343101	Mouse	PMID:24051374
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Crtc2	IGI	MGI:MGI:1343094	Mouse	PMID:24051374
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Crtc2	IDA		Mouse	PMID:24674967
Biological Process	GO:1901998	toxin transport	Crtc2	IMP		Mouse	PMID:23716698

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern