Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Crx

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes CRX
- Mouse genes Crx
- Rat genes Crx
- Zfish genes crx,otx5
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Crx

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Crx	IDA		Mouse	PMID:14613968
Molecular Function	GO:0003677	DNA binding	Crx	IDA		Rat	PMID:9465110\|RGD:1600977
Molecular Function	GO:0003677	DNA binding	crx	IDA		Zfish	PMID:15964232
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	CRX	IDA		Human	PMID:10625658
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Crx	IDA		Mouse	MGI:MGI:3652638\|PMID:16574740
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Crx	IDA		Mouse	PMID:15689355
Molecular Function	GO:0043522	leucine zipper domain binding	CRX	IPI	UniProtKB:P54845	Human	PMID:10887186
Molecular Function	GO:0016922	nuclear receptor binding	Crx	IPI	UniProtKB:Q8R1B8	Mouse	MGI:MGI:3652638\|PMID:16574740
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q8TC57	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:P03410	Human	PMID:22458338
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:O43741	Human	PMID:24722188
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:A1L4F5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:O43741	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:O75603	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:O75716	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:O94817	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:P24863	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:P35219	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:P35711	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:P40306	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:P63241	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q08117	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q14154	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q14CS0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q17RB8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q2TAL8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q5T011-5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q5THT1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q6P2C6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q71RC2-6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q7Z2X4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q96LT7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q96NT3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q96T49	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q9NX04	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q9NYB9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q9UJX0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q9Y221	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:O75603	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:P35219	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:P84022	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:A0A0S2Z5G4	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:A0A0S2Z6P0	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:B4DE54	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:K7EM05	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:O14964	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q53HV7	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q8N9N5-2	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q8N9N5-7	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:O75603	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q9NYB9	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:O43741	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:O75603	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:P24863	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:P35219	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:P35711	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q01974	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q96T49	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:A0A024R8L2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:A5D8V6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:O00560	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:O14964	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:O43247-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:O43711	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:O43741	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:O75593	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:O75603	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:O94888	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:O95007	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:O95376	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:O95416	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:O95947	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:P0CG20	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:P0CW20	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:P0CW24	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:P13807	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:P17931	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:P25786	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:P34130	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:P35680	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:P35711-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:P41225	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:P42773	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:P51687	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:P54253	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:P56693	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:P78412	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q01974	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q08117-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q13952-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q15915	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q17RB8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q2TAL8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q63HR2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q63ZY3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q6NZ36-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q6P088	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q7Z3K3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q86VF2-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q8IYB5-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q8IYR0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q8IYS8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q8N8Y2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q8N9N5-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q8TBB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q8TC57	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q8WU79	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q92734	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q969S2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q96K80	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q9BQY4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q9BUN1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q9BV19	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q9BZE0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q9H503-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q9NP98	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q9NQB0-10	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q9NRN7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q9NZD8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q9UBE0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q9UDX3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q9UFG5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q9UI47-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRX	IPI	UniProtKB:Q9UMX1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Crx	IPI	PR:Q9QXZ7	Mouse	PMID:15689355
Molecular Function	GO:0005515	protein binding	Crx	IPI	PR:Q8R4I1	Mouse	PMID:14613968
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	CRX	IDA		Human	PMID:10625658
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Crx	IDA		Mouse	PMID:20026326
Molecular Function	GO:0043565	sequence-specific DNA binding	otx5	IPI	ZFIN:ZDB-GENE-050105-1	Zfish	PMID:17872382
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	CRX	IDA		Human	PMID:28473536
Cellular Component	GO:0005634	nucleus	Crx	IDA		Mouse	MGI:MGI:3652638\|PMID:16574740
Cellular Component	GO:0005634	nucleus	Crx	IDA		Mouse	PMID:15689355
Cellular Component	GO:0005634	nucleus	Crx	IDA		Rat	PMID:9465110\|RGD:1600977
Cellular Component	GO:0005667	transcription regulator complex	Crx	IDA		Mouse	PMID:15689355
Biological Process	GO:0032922	circadian regulation of gene expression	otx5	IMP	ZFIN:ZDB-MRPHLNO-050420-1	Zfish	PMID:18597743
Biological Process	GO:0032922	circadian regulation of gene expression	otx5	IMP	ZFIN:ZDB-MRPHLNO-050420-1	Zfish	PMID:11753388
Biological Process	GO:0007623	circadian rhythm	Crx	IEP		Rat	PMID:9465110\|RGD:1600977
Biological Process	GO:0001654	eye development	crx	IMP		Zfish	PMID:15081370
Biological Process	GO:0042462	eye photoreceptor cell development	crx	IMP		Zfish	PMID:15081370
Biological Process	GO:0046671	negative regulation of retinal cell programmed cell death	crx	IMP		Zfish	PMID:15081370
Biological Process	GO:0030182	neuron differentiation	crx	IMP		Zfish	PMID:15081370
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	otx5	IMP	ZFIN:ZDB-MRPHLNO-050420-1	Zfish	PMID:15657039
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	otx5	IPI	ZFIN:ZDB-GENE-050105-1	Zfish	PMID:17872382
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	otx5	IGI	RefSeq:NM_001178,RefSeq:NM_007715	Zfish	PMID:15657039
Biological Process	GO:0046534	positive regulation of photoreceptor cell differentiation	Crx	IEP		Rat	PMID:16799048\|RGD:1600973
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	CRX	IDA		Human	PMID:10625658
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Crx	IDA		Mouse	PMID:20026326
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Crx	IGI	MGI:MGI:98743	Mouse	PMID:12407160
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Crx	IDA		Mouse	PMID:12407160
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Crx	IDA		Mouse	PMID:15689355
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Crx	IDA		Mouse	PMID:16539743
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Crx	IDA		Mouse	PMID:14613968
Biological Process	GO:0006355	regulation of DNA-templated transcription	Crx	IDA		Mouse	MGI:MGI:3652638\|PMID:16574740
Biological Process	GO:0060041	retina development in camera-type eye	Crx	IMP		Mouse	PMID:21052544
Biological Process	GO:0007601	visual perception	crx	IMP	ZFIN:ZDB-MRPHLNO-060127-3	Zfish	PMID:20333246

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.