Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CRY2
  • Mouse genes Cry2
  • Rat genes Cry2
  • Zfish genes cry2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cry2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003684	damaged DNA binding	CRY2	IDA		Human	PMID:12627958
Molecular Function	GO:0003677	DNA binding	CRY2	IDA		Human	PMID:12627958
Molecular Function	GO:0071949	FAD binding	Cry2	IDA		Mouse	MGI:MGI:5508675|PMID:23503662
Molecular Function	GO:0019900	kinase binding	Cry2	IPI	UniProtKB:P97313	Mouse	MGI:MGI:5554971|PMID:24158435
Molecular Function	GO:0016922	nuclear receptor binding	Cry2	IPI	UniProtKB:P04150|UniProtKB:P06537	Mouse	MGI:MGI:5302136|PMID:22170608
Molecular Function	GO:0019902	phosphatase binding	CRY2	IPI	UniProtKB:P53041	Human	PMID:9383998
Molecular Function	GO:0005515	protein binding	CRY2	IPI	UniProtKB:P53041	Human	PMID:16790549
Molecular Function	GO:0005515	protein binding	CRY2	IPI	UniProtKB:Q9UKT7	Human	PMID:17463251
Molecular Function	GO:0005515	protein binding	CRY2	IPI	UniProtKB:O76083	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CRY2	IPI	UniProtKB:Q13363-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CRY2	IPI	UniProtKB:Q5JR59	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CRY2	IPI	UniProtKB:P41235	Human	PMID:30530698
Molecular Function	GO:0005515	protein binding	CRY2	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRY2	IPI	UniProtKB:B2RXF5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRY2	IPI	UniProtKB:O15344	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRY2	IPI	UniProtKB:O76083-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRY2	IPI	UniProtKB:O95544	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRY2	IPI	UniProtKB:P0C264	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRY2	IPI	UniProtKB:P0DPK4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRY2	IPI	UniProtKB:P26371	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRY2	IPI	UniProtKB:P60409	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRY2	IPI	UniProtKB:P60410	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRY2	IPI	UniProtKB:Q07627	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRY2	IPI	UniProtKB:Q12933	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRY2	IPI	UniProtKB:Q13077	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRY2	IPI	UniProtKB:Q2TAL6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRY2	IPI	UniProtKB:Q3LI70	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRY2	IPI	UniProtKB:Q5JR59-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRY2	IPI	UniProtKB:Q6A162	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRY2	IPI	UniProtKB:Q6L8G8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRY2	IPI	UniProtKB:Q6L8H1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRY2	IPI	UniProtKB:Q6L8H4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRY2	IPI	UniProtKB:Q701N4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRY2	IPI	UniProtKB:Q8IUG1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRY2	IPI	UniProtKB:Q8WZ60	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRY2	IPI	UniProtKB:Q9BYQ0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRY2	IPI	UniProtKB:Q9BYR5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRY2	IPI	UniProtKB:Q9H0D6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRY2	IPI	UniProtKB:Q9H190	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRY2	IPI	UniProtKB:Q9NRD5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRY2	IPI	UniProtKB:P28799	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CRY2	IPI	UniProtKB:Q99614	Human	PMID:9383998
Molecular Function	GO:0005515	protein binding	Cry2	IPI	UniProtKB:O54943	Mouse	MGI:MGI:5294528|PMID:20840750
Molecular Function	GO:0005515	protein binding	Cry2	IPI	UniProtKB:O08785|UniProtKB:Q9WTL8	Mouse	MGI:MGI:3694308|PMID:16717091
Molecular Function	GO:0005515	protein binding	Cry2	IPI	UniProtKB:P23204|UniProtKB:P35396|UniProtKB:P37238	Mouse	MGI:MGI:6107163|PMID:28683290
Molecular Function	GO:0005515	protein binding	Cry2	IPI	UniProtKB:O35973	Mouse	MGI:MGI:5543956|PMID:24154698
Molecular Function	GO:0005515	protein binding	Cry2	IPI	UniProtKB:O08785|UniProtKB:O35973|UniProtKB:O54943|UniProtKB:O70361	Mouse	MGI:MGI:3027197|PMID:14701732
Molecular Function	GO:0005515	protein binding	Cry2	IPI	UniProtKB:Q9WTL8	Mouse	MGI:MGI:7327235|PMID:21521686
Molecular Function	GO:0005515	protein binding	Cry2	IPI	UniProtKB:Q8BFZ4|UniProtKB:Q8C4V4	Mouse	MGI:MGI:5487698|PMID:23452856
Molecular Function	GO:0005515	protein binding	Cry2	IPI	UniProtKB:Q8C4V4	Mouse	MGI:MGI:3715674|PMID:17462724
Molecular Function	GO:0005515	protein binding	Cry2	IPI	UniProtKB:O35973|UniProtKB:O54943	Mouse	MGI:MGI:5568139|PMID:24737000
Molecular Function	GO:0005515	protein binding	Cry2	IPI	UniProtKB:Q9WTL8	Mouse	MGI:MGI:4881368|PMID:20832105
Molecular Function	GO:0005515	protein binding	Cry2	IPI	UniProtKB:Q9WTL8	Mouse	MGI:MGI:5294528|PMID:20840750
Molecular Function	GO:0005515	protein binding	Cry2	IPI	UniProtKB:P67871	Mouse	MGI:MGI:5700567|PMID:26562092
Molecular Function	GO:0005515	protein binding	Cry2	IPI	UniProtKB:Q9WTL8	Mouse	MGI:MGI:5489023|PMID:23555304
Molecular Function	GO:0005515	protein binding	Cry2	IPI	UniProtKB:Q8BFZ4|UniProtKB:Q8C4V4	Mouse	MGI:MGI:5470183|PMID:23452855
Molecular Function	GO:0005515	protein binding	Cry2	IPI	UniProtKB:O15534|UniProtKB:O54943|UniProtKB:Q9UKT7	Mouse	MGI:MGI:5508675|PMID:23503662
Molecular Function	GO:0005515	protein binding	Cry2	IPI	UniProtKB:O35973|UniProtKB:O54943	Mouse	MGI:MGI:5489023|PMID:23555304
Molecular Function	GO:0005515	protein binding	Cry2	IPI	UniProtKB:O54943|UniProtKB:P06537-1	Mouse	MGI:MGI:5302136|PMID:22170608
Molecular Function	GO:0005515	protein binding	Cry2	IPI	UniProtKB:O54943|UniProtKB:Q9WTL8	Mouse	MGI:MGI:5294528|PMID:20840750
Molecular Function	GO:0005515	protein binding	Cry2	IPI	UniProtKB:O54943	Mouse	MGI:MGI:5508702|PMID:23079727
Molecular Function	GO:0005515	protein binding	Cry2	IPI	UniProtKB:Q3TQ03	Mouse	MGI:MGI:5568140|PMID:24736997
Molecular Function	GO:0005515	protein binding	Cry2	IPI	UniProtKB:Q9UKT7	Mouse	MGI:MGI:3710695|PMID:17463251
Molecular Function	GO:0005515	protein binding	Cry2	IPI	UniProtKB:Q13263|UniProtKB:Q3U1J4|UniProtKB:Q62318|UniProtKB:Q93009	Mouse	MGI:MGI:6253084|PMID:27123980
Molecular Function	GO:0005515	protein binding	Cry2	IPI	UniProtKB:Q9WTL8	Mouse	MGI:MGI:5568139|PMID:24737000
Molecular Function	GO:0005515	protein binding	Cry2	IPI	UniProtKB:O35627|UniProtKB:O54915|UniProtKB:P06537|UniProtKB:P19091|UniProtKB:P35396|UniProtKB:P48281|UniProtKB:P49698	Mouse	MGI:MGI:5913754|PMID:28751364
Molecular Function	GO:0005515	protein binding	Cry2	IPI	UniProtKB:Q9WTL8	Mouse	MGI:MGI:5700567|PMID:26562092
Molecular Function	GO:0005515	protein binding	Cry2	IPI	PR:O35343	Mouse	PMID:15689618
Molecular Function	GO:0005515	protein binding	Cry2	IPI	PR:O35345	Mouse	PMID:15689618
Molecular Function	GO:0019901	protein kinase binding	Cry2	IPI	UniProtKB:Q61214|UniProtKB:Q9WV60	Mouse	MGI:MGI:4461092|PMID:20123978
Molecular Function	GO:0003697	single-stranded DNA binding	CRY2	IDA		Human	PMID:12627958
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Cry2	IDA		Mouse	MGI:MGI:5014424|PMID:21680841
Cellular Component	GO:0005737	cytoplasm	cry2	IDA		Zfish	PMID:25630924
Cellular Component	GO:0005829	cytosol	CRY2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005576	extracellular region	CRY2	IDA		Human	PMID:9753616
Cellular Component	GO:0005739	mitochondrion	Cry2	IDA		Mouse	MGI:MGI:1314997|PMID:9801304
Cellular Component	GO:0016607	nuclear speck	CRY2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Cry2	IDA		Mouse	MGI:MGI:1314997|PMID:9801304
Cellular Component	GO:0005634	nucleus	Cry2	IDA		Mouse	MGI:MGI:5294528|PMID:20840750
Cellular Component	GO:0005634	nucleus	Cry2	IDA		Mouse	PMID:15689618
Cellular Component	GO:0005634	nucleus	cry2	IDA		Zfish	PMID:25630924
Cellular Component	GO:0005667	transcription regulator complex	cry2	IPI	UniProtKB:Q8JIG3	Zfish	PMID:12354100
Biological Process	GO:0032922	circadian regulation of gene expression	Cry2	IMP		Mouse	MGI:MGI:5490394|PMID:23616524
Biological Process	GO:0032922	circadian regulation of gene expression	Cry2	IMP		Mouse	MGI:MGI:3843127|PMID:19299583
Biological Process	GO:0032922	circadian regulation of gene expression	Cry2	IGI	UniProtKB:P97784	Mouse	MGI:MGI:5302136|PMID:22170608
Biological Process	GO:0007623	circadian rhythm	Cry2	IMP		Mouse	MGI:MGI:6294193|PMID:29561690
Biological Process	GO:0007623	circadian rhythm	Cry2	IMP		Mouse	MGI:MGI:4461092|PMID:20123978
Biological Process	GO:0007623	circadian rhythm	Cry2	IMP	MGI:MGI:2181206	Mouse	PMID:12024206
Biological Process	GO:0007623	circadian rhythm	Cry2	IMP		Mouse	PMID:17264215
Biological Process	GO:0007623	circadian rhythm	Cry2	IEP		Rat	PMID:11804325|RGD:632584
Biological Process	GO:0043153	entrainment of circadian clock by photoperiod	Cry2	IMP		Mouse	MGI:MGI:5490394|PMID:23616524
Biological Process	GO:0042593	glucose homeostasis	Cry2	IGI	UniProtKB:P97784	Mouse	MGI:MGI:5302136|PMID:22170608
Biological Process	GO:0019915	lipid storage	Cry2	IGI	UniProtKB:P97784	Mouse	MGI:MGI:5495865|PMID:23531614
Biological Process	GO:0042754	negative regulation of circadian rhythm	Cry2	IDA		Mouse	MGI:MGI:4410413|PMID:19605937
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	CRY2	IDA		Human	PMID:12397359
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Cry2	IDA		Mouse	MGI:MGI:4410413|PMID:19605937
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Cry2	IDA		Mouse	MGI:MGI:5568140|PMID:24736997
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Cry2	IGI	UniProtKB:P97784	Mouse	MGI:MGI:5302136|PMID:22170608
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Cry2	IDA		Mouse	MGI:MGI:5559671|PMID:14645221
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Cry2	IMP		Mouse	MGI:MGI:6107163|PMID:28683290
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Cry2	IDA		Mouse	MGI:MGI:5532917|PMID:17310242
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Cry2	IMP		Mouse	MGI:MGI:5913754|PMID:28751364
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Cry2	IDA		Mouse	MGI:MGI:5553247|PMID:12738229
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	cry2	IDA		Zfish	PMID:12354100
Biological Process	GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	Cry2	IGI	UniProtKB:P97784	Mouse	MGI:MGI:5302136|PMID:22170608
Biological Process	GO:2000850	negative regulation of glucocorticoid secretion	Cry2	IGI	UniProtKB:P97784	Mouse	MGI:MGI:5495865|PMID:23531614
Biological Process	GO:0032515	negative regulation of phosphoprotein phosphatase activity	CRY2	IDA		Human	PMID:9383998
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	CRY2	IDA		Human	PMID:12397359
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	CRY2	IDA		Human	PMID:14672706
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	CRY2	IDA		Human	PMID:15147242
Biological Process	GO:0006606	protein import into nucleus	Cry2	IPI	PR:O54943	Mouse	PMID:15689618
Biological Process	GO:0042752	regulation of circadian rhythm	Cry2	IMP		Mouse	MGI:MGI:1334825|PMID:10217146
Biological Process	GO:0042752	regulation of circadian rhythm	Cry2	IMP		Mouse	MGI:MGI:5490394|PMID:23616524
Biological Process	GO:0042752	regulation of circadian rhythm	Cry2	IMP	UniProtKB:P97784	Mouse	MGI:MGI:5567898|PMID:23575670
Biological Process	GO:2000118	regulation of sodium-dependent phosphate transport	CRY2	IDA		Human	PMID:9753616
Biological Process	GO:0014823	response to activity	Cry2	IMP		Mouse	MGI:MGI:6107163|PMID:28683290
Biological Process	GO:0032868	response to insulin	Cry2	IGI	UniProtKB:P97784	Mouse	MGI:MGI:5495865|PMID:23531614
Biological Process	GO:0009416	response to light stimulus	CRY2	IMP		Human	PMID:15751956
Biological Process	GO:0009416	response to light stimulus	Cry2	IMP		Mouse	MGI:MGI:6294193|PMID:29561690
Biological Process	GO:0009416	response to light stimulus	cry2	IDA		Zfish	PMID:16176122
Biological Process	GO:0009266	response to temperature stimulus	cry2	IDA		Zfish	PMID:16176122

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern