Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CRYBA1
  • Mouse genes Cryba1
  • Rat genes Cryba1
  • Zfish genes cryba1a,cryba1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cryba1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	Cryba1	IPI	PR:P02525	Mouse	PMID:14717595
Molecular Function	GO:0005515	protein binding	CRYBA1	IPI	UniProtKB:P02511	Human	PMID:17046756
Molecular Function	GO:0005515	protein binding	CRYBA1	IPI	UniProtKB:P53674	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	CRYBA1	IPI	UniProtKB:P26998	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CRYBA1	IPI	UniProtKB:P53674	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CRYBA1	IPI	UniProtKB:Q93062	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CRYBA1	IPI	UniProtKB:Q9BQY4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CRYBA1	IPI	UniProtKB:P53674	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	CRYBA1	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRYBA1	IPI	UniProtKB:O75360	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRYBA1	IPI	UniProtKB:O75593	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRYBA1	IPI	UniProtKB:P26998	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRYBA1	IPI	UniProtKB:P31273	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRYBA1	IPI	UniProtKB:P43320	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRYBA1	IPI	UniProtKB:Q03989	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRYBA1	IPI	UniProtKB:Q08AM6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRYBA1	IPI	UniProtKB:Q14847-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRYBA1	IPI	UniProtKB:Q3SY46	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRYBA1	IPI	UniProtKB:Q52LG2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRYBA1	IPI	UniProtKB:Q86UR1-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRYBA1	IPI	UniProtKB:Q8IUC1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRYBA1	IPI	UniProtKB:Q8TCT0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRYBA1	IPI	UniProtKB:Q96J87-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRYBA1	IPI	UniProtKB:Q9H503-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRYBA1	IPI	UniProtKB:Q9H8W4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CRYBA1	IPI	UniProtKB:Q9Y6H1	Human	PMID:32296183
Cellular Component	GO:0005737	cytoplasm	Cryba1	IDA		Rat	PMID:17931883|RGD:2303652
Cellular Component	GO:0005764	lysosome	Cryba1	IDA		Rat	PMID:21266465|RGD:126925759
Cellular Component	GO:0005634	nucleus	Cryba1	IDA		Rat	PMID:17931883|RGD:2303652
Biological Process	GO:0043010	camera-type eye development	Cryba1	IMP	MGI:MGI:1857969	Mouse	PMID:10585769
Biological Process	GO:0002088	lens development in camera-type eye	Cryba1	IEP		Rat	PMID:2753045|RGD:1298814
Biological Process	GO:0001818	negative regulation of cytokine production	Cryba1	IMP		Rat	PMID:21993393|RGD:10059647
Biological Process	GO:0070373	negative regulation of ERK1 and ERK2 cascade	Cryba1	IMP		Rat	PMID:21993393|RGD:10059647
Biological Process	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling	Cryba1	IMP		Rat	PMID:21993393|RGD:10059647
Biological Process	GO:0051898	negative regulation of protein kinase B signaling	Cryba1	IMP		Rat	PMID:21993393|RGD:10059647
Biological Process	GO:0032007	negative regulation of TOR signaling	Cryba1	IMP		Rat	PMID:21993393|RGD:10059647
Biological Process	GO:0006909	phagocytosis	Cryba1	IMP		Rat	PMID:21266465|RGD:126925759
Biological Process	GO:2000210	positive regulation of anoikis	Cryba1	IMP		Rat	PMID:21993393|RGD:10059647
Biological Process	GO:0010506	regulation of autophagy	Cryba1	IMP		Rat	PMID:21266465|RGD:126925759

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern