Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Csf1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes CSF1
- Mouse genes Csf1
- Rat genes Csf1
- Zfish genes csf1a,csf1b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Csf1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005125	cytokine activity	CSF1	IDA		Human	PMID:10652277
Molecular Function	GO:0005125	cytokine activity	CSF1	IDA		Human	PMID:2460758
Molecular Function	GO:0008083	growth factor activity	CSF1	IDA		Human	PMID:2460758
Molecular Function	GO:0042802	identical protein binding	CSF1	IPI	UniProtKB:P09603	Human	PMID:22153499
Molecular Function	GO:0042802	identical protein binding	CSF1	IPI	UniProtKB:P09603	Human	PMID:22902366
Molecular Function	GO:0042802	identical protein binding	Csf1	IPI	UniProtKB:P07141	Mouse	MGI:MGI:5914909\|PMID:22902366
Molecular Function	GO:0042802	identical protein binding	Csf1	IPI	RGD:621063	Rat	PMID:8357831\|RGD:727729
Molecular Function	GO:0005157	macrophage colony-stimulating factor receptor binding	Csf1	IPI	UniProtKB:P09581	Mouse	MGI:MGI:3836228\|PMID:19017797
Molecular Function	GO:0005157	macrophage colony-stimulating factor receptor binding	Csf1	IPI	PR:P09581	Mouse	PMID:2408759
Molecular Function	GO:0005515	protein binding	CSF1	IPI	UniProtKB:P07333	Human	PMID:22153499
Molecular Function	GO:0005515	protein binding	CSF1	IPI	UniProtKB:P09581	Human	PMID:22153499
Molecular Function	GO:0005515	protein binding	CSF1	IPI	UniProtKB:P07333	Human	PMID:22483114
Molecular Function	GO:0005515	protein binding	CSF1	IPI	UniProtKB:P09581	Human	PMID:22826234
Molecular Function	GO:0005515	protein binding	CSF1	IPI	UniProtKB:P0CW72	Human	PMID:22826234
Molecular Function	GO:0005515	protein binding	CSF1	IPI	UniProtKB:P03228	Human	PMID:22902366
Molecular Function	GO:0005515	protein binding	CSF1	IPI	UniProtKB:P07333	Human	PMID:22902366
Molecular Function	GO:0005515	protein binding	CSF1	IPI	UniProtKB:O43765	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CSF1	IPI	UniProtKB:Q13643	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CSF1	IPI	UniProtKB:Q7Z3S9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CSF1	IPI	UniProtKB:P07333	Human	PMID:26235028
Molecular Function	GO:0005515	protein binding	CSF1	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CSF1	IPI	UniProtKB:O43765	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CSF1	IPI	UniProtKB:P60410	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CSF1	IPI	UniProtKB:Q07627	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CSF1	IPI	UniProtKB:Q5JR59-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Csf1	IPI	UniProtKB:P05480	Mouse	MGI:MGI:3696626\|PMID:16267818
Molecular Function	GO:0005515	protein binding	Csf1	IPI	UniProtKB:P09581	Mouse	MGI:MGI:5918492\|PMID:22153499
Molecular Function	GO:0005515	protein binding	Csf1	IPI	UniProtKB:P09581	Mouse	MGI:MGI:3836228\|PMID:19017797
Molecular Function	GO:0005515	protein binding	Csf1	IPI	UniProtKB:P03228	Mouse	MGI:MGI:5914909\|PMID:22902366
Molecular Function	GO:0005515	protein binding	Csf1	IPI	UniProtKB:Q60771\|UniProtKB:Q8C161\|UniProtKB:Q9JHU4	Mouse	MGI:MGI:3696626\|PMID:16267818
Molecular Function	GO:0005515	protein binding	Csf1	IPI	PR:P23611	Mouse	PMID:25331958
Molecular Function	GO:0042803	protein homodimerization activity	CSF1	IDA		Human	PMID:3264878
Molecular Function	GO:0042803	protein homodimerization activity	Csf1	IPI	UniProtKB:P07141	Mouse	MGI:MGI:3836228\|PMID:19017797
Cellular Component	GO:1990682	CSF1-CSF1R complex	Csf1	IDA		Mouse	MGI:MGI:3836228\|PMID:19017797
Cellular Component	GO:0005576	extracellular region	Csf1	IDA		Rat	PMID:16673407\|RGD:151665782
Cellular Component	GO:0005615	extracellular space	CSF1	IDA		Human	PMID:2460758
Cellular Component	GO:0005615	extracellular space	Csf1	HDA		Mouse	MGI:MGI:5640941\|PMID:24006456
Cellular Component	GO:0005615	extracellular space	Csf1	IDA		Rat	PMID:22846308\|RGD:7257592
Cellular Component	GO:0016604	nuclear body	CSF1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0048471	perinuclear region of cytoplasm	CSF1	IDA		Human	PMID:1739124
Cellular Component	GO:0005886	plasma membrane	CSF1	IDA		Human	GO_REF:0000052
Biological Process	GO:0060444	branching involved in mammary gland duct morphogenesis	Csf1	IMP	MGI:MGI:1856333	Mouse	PMID:10804170
Biological Process	GO:0008283	cell population proliferation	Csf1	IDA		Rat	PMID:20628067\|RGD:5131511
Biological Process	GO:0071374	cellular response to parathyroid hormone stimulus	Csf1	IEP		Rat	PMID:8304053\|RGD:151665809
Biological Process	GO:0003006	developmental process involved in reproduction	Csf1	IMP		Mouse	MGI:MGI:3614922\|PMID:16237150
Biological Process	GO:0048873	homeostasis of number of cells within a tissue	Csf1	IMP	MGI:MGI:1856333	Mouse	PMID:9215625
Biological Process	GO:0038145	macrophage colony-stimulating factor signaling pathway	Csf1	IDA		Mouse	MGI:MGI:3836228\|PMID:19017797
Biological Process	GO:0030225	macrophage differentiation	Csf1	IMP	MGI:MGI:1856333	Mouse	PMID:9215625
Biological Process	GO:0030225	macrophage differentiation	Csf1	IEP		Rat	PMID:12379742\|RGD:628338
Biological Process	GO:0030225	macrophage differentiation	Csf1	IDA		Rat	PMID:20628067\|RGD:5131511
Biological Process	GO:0061519	macrophage homeostasis	Csf1	IMP	MGI:MGI:1856333	Mouse	PMID:9215625
Biological Process	GO:0060763	mammary duct terminal end bud growth	Csf1	IMP	MGI:MGI:1856333	Mouse	PMID:10804170
Biological Process	GO:0060611	mammary gland fat development	Csf1	IMP	MGI:MGI:1856333	Mouse	PMID:10804170
Biological Process	GO:0061518	microglial cell proliferation	Csf1	IGI	UniProtKB:P09581	Mouse	MGI:MGI:6274943\|PMID:23392676
Biological Process	GO:0030224	monocyte differentiation	Csf1	IMP	MGI:MGI:1856333	Mouse	PMID:9215625
Biological Process	GO:0035702	monocyte homeostasis	Csf1	IMP	MGI:MGI:1856333	Mouse	PMID:9215625
Biological Process	GO:0097529	myeloid leukocyte migration	Csf1	IGI	MGI:MGI:97306	Mouse	PMID:17053831
Biological Process	GO:1901215	negative regulation of neuron death	CSF1	IDA		Human	PMID:8922060
Biological Process	GO:0001780	neutrophil homeostasis	Csf1	IMP	MGI:MGI:1856333	Mouse	PMID:9215625
Biological Process	GO:0042476	odontogenesis	Csf1	IMP		Rat	PMID:12379742\|RGD:628338
Biological Process	GO:0001503	ossification	Csf1	IMP		Rat	PMID:12379742\|RGD:628338
Biological Process	GO:0030316	osteoclast differentiation	CSF1	IDA		Human	PMID:18606301
Biological Process	GO:0030316	osteoclast differentiation	Csf1	IGI	MGI:MGI:1100089	Mouse	PMID:17053831
Biological Process	GO:0030316	osteoclast differentiation	Csf1	IDA		Mouse	PMID:17442941
Biological Process	GO:0030316	osteoclast differentiation	Csf1	IMP	MGI:MGI:1856333	Mouse	PMID:9215625
Biological Process	GO:0030316	osteoclast differentiation	Csf1	IMP		Rat	PMID:12379742\|RGD:628338
Biological Process	GO:0002158	osteoclast proliferation	Csf1	IDA		Mouse	PMID:22451653
Biological Process	GO:0030335	positive regulation of cell migration	Csf1	IMP		Rat	PMID:8304053\|RGD:151665809
Biological Process	GO:0008284	positive regulation of cell population proliferation	CSF1	IDA		Human	PMID:10652277
Biological Process	GO:0001954	positive regulation of cell-matrix adhesion	Csf1	IGI	MGI:MGI:97306	Mouse	PMID:17053831
Biological Process	GO:0010628	positive regulation of gene expression	CSF1	IDA		Human	PMID:10666185
Biological Process	GO:0010628	positive regulation of gene expression	CSF1	IDA		Human	PMID:1739124
Biological Process	GO:0010628	positive regulation of gene expression	Csf1	IDA		Mouse	MGI:MGI:6294196\|PMID:30687013
Biological Process	GO:0002687	positive regulation of leukocyte migration	Csf1	IGI	MGI:MGI:97306	Mouse	PMID:17053831
Biological Process	GO:0010759	positive regulation of macrophage chemotaxis	CSF1	IDA		Human	PMID:19100238
Biological Process	GO:1902228	positive regulation of macrophage colony-stimulating factor signaling pathway	CSF1	IDA		Human	PMID:19100238
Biological Process	GO:0010744	positive regulation of macrophage derived foam cell differentiation	CSF1	IDA		Human	PMID:17244792
Biological Process	GO:0045651	positive regulation of macrophage differentiation	CSF1	IDA		Human	PMID:2460758
Biological Process	GO:0045651	positive regulation of macrophage differentiation	Csf1	IMP	MGI:MGI:1856333	Mouse	PMID:9215625
Biological Process	GO:1905523	positive regulation of macrophage migration	CSF1	IMP		Human	PMID:24415783
Biological Process	GO:0120041	positive regulation of macrophage proliferation	Csf1	IMP		Rat	PMID:8304053\|RGD:151665809
Biological Process	GO:1904141	positive regulation of microglial cell migration	CSF1	IDA		Human	PMID:19100238
Biological Process	GO:0045657	positive regulation of monocyte differentiation	Csf1	IMP	MGI:MGI:1856333	Mouse	PMID:9215625
Biological Process	GO:0071677	positive regulation of mononuclear cell migration	Csf1	IMP		Rat	PMID:11499013\|RGD:151665786
Biological Process	GO:0032946	positive regulation of mononuclear cell proliferation	CSF1	IDA		Human	PMID:2460758
Biological Process	GO:0040018	positive regulation of multicellular organism growth	Csf1	IMP	MGI:MGI:1856333	Mouse	PMID:12865350
Biological Process	GO:0042488	positive regulation of odontogenesis of dentin-containing tooth	Csf1	IMP	MGI:MGI:1856333	Mouse	PMID:12865350
Biological Process	GO:0045672	positive regulation of osteoclast differentiation	CSF1	IDA		Human	PMID:15304486
Biological Process	GO:0045672	positive regulation of osteoclast differentiation	Csf1	IGI	MGI:MGI:1100089	Mouse	PMID:21048959
Biological Process	GO:0045672	positive regulation of osteoclast differentiation	Csf1	IGI	MGI:MGI:1100089	Mouse	PMID:17053831
Biological Process	GO:0045672	positive regulation of osteoclast differentiation	Csf1	IMP	MGI:MGI:1856333	Mouse	PMID:9215625
Biological Process	GO:0045672	positive regulation of osteoclast differentiation	Csf1	IDA		Mouse	PMID:15657444
Biological Process	GO:0045860	positive regulation of protein kinase activity	Csf1	IGI	MGI:MGI:97306	Mouse	PMID:17053831
Biological Process	GO:0051247	positive regulation of protein metabolic process	CSF1	IDA		Human	PMID:1739124
Biological Process	GO:0046579	positive regulation of Ras protein signal transduction	Csf1	IDA		Mouse	PMID:17053831
Biological Process	GO:0007265	Ras protein signal transduction	Csf1	IDA		Mouse	PMID:17053831
Biological Process	GO:0030278	regulation of ossification	Csf1	IMP	MGI:MGI:1856333	Mouse	PMID:12865350
Biological Process	GO:0002931	response to ischemia	CSF1	IDA		Human	PMID:8922060
Biological Process	GO:0032496	response to lipopolysaccharide	Csf1	IEP		Rat	PMID:24882100\|RGD:151667420
Biological Process	GO:0009612	response to mechanical stimulus	Csf1	IEP		Rat	PMID:20833686\|RGD:151665823
Biological Process	GO:0014070	response to organic cyclic compound	Csf1	IEP		Rat	PMID:19219684\|RGD:151665779
Biological Process	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	CSF1	IDA		Human	PMID:19100238

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.