Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CSPG4
  • Mouse genes Cspg4
  • Rat genes Cspg4
  • Zfish genes cspg4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cspg4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005518	collagen binding	Cspg4	IPI	UniProtKB:P20908	Rat	PMID:9099729|RGD:8553708
Molecular Function	GO:0015026	coreceptor activity	Cspg4	IDA		Mouse	PMID:26437238
Molecular Function	GO:0005515	protein binding	Cspg4	IPI	UniProtKB:P23819|UniProtKB:Q925T6|UniProtKB:Q9WTW1	Mouse	MGI:MGI:2449831|PMID:12458226
Molecular Function	GO:0005515	protein binding	Cspg4	IPI	PR:Q8CDJ8	Mouse	PMID:26437238
Molecular Function	GO:0019901	protein kinase binding	CSPG4	IPI	UniProtKB:Q07912	Human	PMID:10587647
Cellular Component	GO:0042995	cell projection	Cspg4	IDA		Mouse	PMID:26437238
Cellular Component	GO:0042995	cell projection	Cspg4	IDA		Mouse	PMID:23447615
Cellular Component	GO:0009986	cell surface	CSPG4	HDA		Human	PMID:19581412
Cellular Component	GO:0062023	collagen-containing extracellular matrix	CSPG4	HDA		Human	PMID:27068509
Cellular Component	GO:0062023	collagen-containing extracellular matrix	CSPG4	HDA		Human	PMID:28675934
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Cspg4	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0070062	extracellular exosome	CSPG4	HDA		Human	PMID:23533145
Cellular Component	GO:0005925	focal adhesion	CSPG4	HDA		Human	PMID:21423176
Cellular Component	GO:0005654	nucleoplasm	CSPG4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	CSPG4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Cspg4	IDA		Mouse	PMID:11668599
Cellular Component	GO:0005886	plasma membrane	Cspg4	IDA		Rat	PMID:17565360|RGD:5686869
Cellular Component	GO:0001726	ruffle	Cspg4	IDA		Mouse	PMID:26437238
Biological Process	GO:0008347	glial cell migration	Cspg4	IDA		Mouse	PMID:10366628
Biological Process	GO:0006954	inflammatory response	Cspg4	IMP		Rat	PMID:19878709|RGD:5686864
Biological Process	GO:0035556	intracellular signal transduction	CSPG4	IDA		Human	PMID:10587647
Biological Process	GO:0010977	negative regulation of neuron projection development	Cspg4	IMP		Rat	PMID:21105148|RGD:5686866
Biological Process	GO:0016322	neuron remodeling	Cspg4	IDA		Rat	PMID:12526031|RGD:632591
Biological Process	GO:0048008	platelet-derived growth factor receptor signaling pathway	Cspg4	IDA		Mouse	PMID:26437238
Biological Process	GO:0043410	positive regulation of MAPK cascade	Cspg4	IMP	MGI:MGI:2153094	Mouse	PMID:10036240
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	CSPG4	IDA		Human	PMID:10587647
Biological Process	GO:0010226	response to lithium ion	Cspg4	IEP		Rat	PMID:19439244|RGD:5686861
Biological Process	GO:0097178	ruffle assembly	Cspg4	IDA		Mouse	PMID:26437238
Biological Process	GO:0006929	substrate-dependent cell migration	Cspg4	IGI	MGI:MGI:1924307	Mouse	PMID:26437238

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern