Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CSRP3
  • Mouse genes Csrp3
  • Rat genes Csrp3
  • Zfish genes csrp3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Csrp3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042805	actinin binding	Csrp3	IDA		Mouse	MGI:MGI:2447926|PMID:12507422
Molecular Function	GO:0042802	identical protein binding	CSRP3	IPI	UniProtKB:P50461	Human	PMID:24860983
Molecular Function	GO:0043426	MRF binding	Csrp3	IDA		Rat	PMID:9234731|RGD:10047266
Molecular Function	GO:0005515	protein binding	CSRP3	IPI	UniProtKB:Q86WU2	Human	PMID:12127981
Molecular Function	GO:0005515	protein binding	CSRP3	IPI	UniProtKB:P35609	Human	PMID:15205937
Molecular Function	GO:0005515	protein binding	CSRP3	IPI	UniProtKB:Q86VF7	Human	PMID:15205937
Molecular Function	GO:0005515	protein binding	CSRP3	IPI	UniProtKB:O15273	Human	PMID:15582318
Molecular Function	GO:0005515	protein binding	CSRP3	IPI	UniProtKB:O15273	Human	PMID:24860983
Molecular Function	GO:0005515	protein binding	CSRP3	IPI	UniProtKB:P35609	Human	PMID:24860983
Molecular Function	GO:0005515	protein binding	CSRP3	IPI	UniProtKB:Q9Y281	Human	PMID:24860983
Molecular Function	GO:0005515	protein binding	CSRP3	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Csrp3	IPI	UniProtKB:Q9CQM9	Mouse	MGI:MGI:4461873|PMID:18258855
Molecular Function	GO:0005515	protein binding	Csrp3	IPI	UniProtKB:Q7TNG8	Mouse	MGI:MGI:3687894|PMID:12127981
Molecular Function	GO:0005515	protein binding	Csrp3	IPI	PR:P63328	Mouse	PMID:15665106
Molecular Function	GO:0005515	protein binding	Csrp3	IPI	UniProtKB:P10085	Rat	PMID:10751147|RGD:12050121
Molecular Function	GO:0005515	protein binding	Csrp3	IPI	UniProtKB:P11277	Rat	PMID:10751147|RGD:12050121
Molecular Function	GO:0005515	protein binding	Csrp3	IPI	UniProtKB:P10085	Rat	PMID:9234731|RGD:10047266
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	Csrp3	IPI	UniProtKB:P10085	Rat	PMID:9234731|RGD:10047266
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	Csrp3	IPI	UniProtKB:P12979	Rat	PMID:9234731|RGD:10047266
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	Csrp3	IPI	UniProtKB:P19335	Rat	PMID:9234731|RGD:10047266
Molecular Function	GO:0008307	structural constituent of muscle	CSRP3	IMP		Human	PMID:12507422
Molecular Function	GO:0008307	structural constituent of muscle	Csrp3	IMP		Mouse	MGI:MGI:2447926|PMID:12507422
Molecular Function	GO:0031433	telethonin binding	CSRP3	IDA		Human	PMID:12507422
Molecular Function	GO:0031433	telethonin binding	CSRP3	IPI	UniProtKB:O15273	Human	PMID:15582318
Molecular Function	GO:0031433	telethonin binding	Csrp3	IPI	UniProtKB:O70548	Mouse	MGI:MGI:2447926|PMID:12507422
Cellular Component	GO:0005737	cytoplasm	Csrp3	IDA		Rat	PMID:11113014|RGD:1598503
Cellular Component	GO:0005737	cytoplasm	Csrp3	IDA		Rat	PMID:9234731|RGD:10047266
Cellular Component	GO:0005829	cytosol	CSRP3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	CSRP3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Csrp3	IDA		Rat	PMID:11113014|RGD:1598503
Cellular Component	GO:0005634	nucleus	Csrp3	IDA		Rat	PMID:9234731|RGD:10047266
Cellular Component	GO:0030018	Z disc	CSRP3	IDA		Human	PMID:12507422
Cellular Component	GO:0030018	Z disc	Csrp3	IDA		Mouse	PMID:15665106
Cellular Component	GO:0030018	Z disc	Csrp3	IDA		Rat	PMID:12507422|RGD:734841
Biological Process	GO:0001974	blood vessel remodeling	Csrp3	IEP		Rat	PMID:16519896|RGD:1598504
Biological Process	GO:0060048	cardiac muscle contraction	CSRP3	IMP		Human	PMID:12507422
Biological Process	GO:0060048	cardiac muscle contraction	Csrp3	IMP		Mouse	MGI:MGI:2447926|PMID:12507422
Biological Process	GO:0003300	cardiac muscle hypertrophy	CSRP3	IMP		Human	PMID:12507422
Biological Process	GO:0048738	cardiac muscle tissue development	Csrp3	IGI	MGI:MGI:97622	Mouse	PMID:10555147
Biological Process	GO:0055003	cardiac myofibril assembly	Csrp3	IMP		Mouse	MGI:MGI:2447926|PMID:12507422
Biological Process	GO:0035995	detection of muscle stretch	CSRP3	IMP		Human	PMID:12507422
Biological Process	GO:0035995	detection of muscle stretch	Csrp3	IMP		Mouse	MGI:MGI:2447926|PMID:12507422
Biological Process	GO:0042593	glucose homeostasis	Csrp3	IMP	MGI:MGI:1858015	Mouse	PMID:29634311
Biological Process	GO:0060047	heart contraction	csrp3	IMP	ZFIN:ZDB-MRPHLNO-091216-14	Zfish	PMID:19800866
Biological Process	GO:0007507	heart development	Csrp3	IGI	MGI:MGI:1328311	Mouse	PMID:28706255
Biological Process	GO:0006954	inflammatory response	Csrp3	IMP	MGI:MGI:1858015	Mouse	PMID:29634311
Biological Process	GO:0008286	insulin receptor signaling pathway	Csrp3	IMP	MGI:MGI:1858015	Mouse	PMID:29634311
Biological Process	GO:0006874	intracellular calcium ion homeostasis	Csrp3	IGI	MGI:MGI:97622	Mouse	PMID:10555147
Biological Process	GO:0046716	muscle cell cellular homeostasis	Csrp3	IGI	MGI:MGI:97622	Mouse	PMID:10555147
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	Csrp3	IDA		Rat	PMID:9234731|RGD:10047266
Biological Process	GO:0010831	positive regulation of myotube differentiation	Csrp3	IDA		Rat	PMID:9234731|RGD:10047266
Biological Process	GO:0010831	positive regulation of myotube differentiation	Csrp3	IGI	UniProtKB:P10085	Rat	PMID:9234731|RGD:10047266
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	CSRP3	IGI	UniProtKB:P10085	Human	PMID:9234731
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	CSRP3	IGI	UniProtKB:P19335	Human	PMID:9234731
Biological Process	GO:0070528	protein kinase C signaling	Csrp3	IGI	MGI:MGI:1097717	Mouse	PMID:27353086
Biological Process	GO:0033365	protein localization to organelle	CSRP3	IMP		Human	PMID:12507422
Biological Process	GO:0033365	protein localization to organelle	Csrp3	IMP		Mouse	MGI:MGI:2447926|PMID:12507422
Biological Process	GO:1903076	regulation of protein localization to plasma membrane	Csrp3	IMP	MGI:MGI:1858015	Mouse	PMID:29634311
Biological Process	GO:0002026	regulation of the force of heart contraction	Csrp3	IGI	MGI:MGI:97622	Mouse	PMID:10555147
Biological Process	GO:0035994	response to muscle stretch	csrp3	IMP	ZFIN:ZDB-GENO-200123-8	Zfish	PMID:30826063
Biological Process	GO:0045214	sarcomere organization	csrp3	IMP	ZFIN:ZDB-MRPHLNO-091216-14	Zfish	PMID:19800866
Biological Process	GO:0033292	T-tubule organization	Csrp3	IGI	MGI:MGI:1328311	Mouse	PMID:28706255

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern