Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CSTB
  • Mouse genes Cstb
  • Rat genes Cstb
  • Zfish genes cst14a.1,cst14a.2,cst14b.1,cst14b.2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cstb

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004869	cysteine-type endopeptidase inhibitor activity	CSTB	IDA		Human	PMID:3488317
Molecular Function	GO:0004869	cysteine-type endopeptidase inhibitor activity	CSTB	IDA		Human	PMID:6203523
Molecular Function	GO:0004866	endopeptidase inhibitor activity	CSTB	IDA		Human	PMID:3053245
Molecular Function	GO:0002020	protease binding	CSTB	IDA		Human	PMID:11514663
Molecular Function	GO:0002020	protease binding	CSTB	IPI	UniProtKB:P09668	Human	PMID:6203523
Molecular Function	GO:0005515	protein binding	Cstb	IPI	UniProtKB:Q5M820	Rat	PMID:1239805|RGD:8553284
Molecular Function	GO:0005515	protein binding	Cstb	IPI	UniProtKB:P00441	Rat	PMID:24234043|RGD:126781732
Molecular Function	GO:0003723	RNA binding	CSTB	HDA		Human	PMID:22658674
Cellular Component	GO:0062023	collagen-containing extracellular matrix	CSTB	HDA		Human	PMID:25037231
Cellular Component	GO:0062023	collagen-containing extracellular matrix	CSTB	HDA		Human	PMID:28675934
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Cstb	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0005737	cytoplasm	CSTB	IDA		Human	PMID:11139332
Cellular Component	GO:0005829	cytosol	CSTB	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	CSTB	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	CSTB	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	CSTB	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	CSTB	HDA		Human	PMID:23580065
Cellular Component	GO:0005615	extracellular space	CSTB	IDA		Human	PMID:3488317
Cellular Component	GO:0005730	nucleolus	CSTB	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	CSTB	IDA		Human	PMID:11139332
Biological Process	GO:0008344	adult locomotory behavior	Cstb	IMP	MGI:MGI:1861915	Mouse	PMID:9806543
Biological Process	GO:0010466	negative regulation of peptidase activity	CSTB	IDA		Human	PMID:6203523
Biological Process	GO:0045861	negative regulation of proteolysis	CSTB	IDA		Human	PMID:3488317

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern