Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CTBP1
  • Mouse genes Ctbp1
  • Rat genes Ctbp1
  • Zfish genes ctbp1,zgc:136929
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ctbp1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Ctbp1	IDA		Mouse	PMID:17392792
Molecular Function	GO:0140297	DNA-binding transcription factor binding	CTBP1	IPI	UniProtKB:Q5W1J5	Human	PMID:16609867
Molecular Function	GO:0140297	DNA-binding transcription factor binding	CTBP1	IPI	UniProtKB:P51858	Human	PMID:19162039
Molecular Function	GO:0042802	identical protein binding	CTBP1	IPI	UniProtKB:Q13363	Human	PMID:21988832
Molecular Function	GO:0042802	identical protein binding	CTBP1	IPI	UniProtKB:Q13363	Human	PMID:24722188
Molecular Function	GO:0042802	identical protein binding	CTBP1	IPI	UniProtKB:Q13363	Human	PMID:31041561
Molecular Function	GO:0042802	identical protein binding	CTBP1	IPI	UniProtKB:Q13363	Human	PMID:31515488
Molecular Function	GO:0051287	NAD binding	Ctbp1	IDA		Rat	PMID:19351597|RGD:8553313
Molecular Function	GO:0030165	PDZ domain binding	Ctbp1	IPI	UniProtKB:P29476	Rat	PMID:11590170|RGD:12793005
Molecular Function	GO:0005515	protein binding	CTBP1	IPI	UniProtKB:Q03112	Human	PMID:11568182
Molecular Function	GO:0005515	protein binding	CTBP1	IPI	UniProtKB:Q96JB3	Human	PMID:12052894
Molecular Function	GO:0005515	protein binding	CTBP1	IPI	UniProtKB:Q03112-1	Human	PMID:15897867
Molecular Function	GO:0005515	protein binding	CTBP1	IPI	UniProtKB:Q99708	Human	PMID:16287852
Molecular Function	GO:0005515	protein binding	CTBP1	IPI	UniProtKB:O95785	Human	PMID:16702210
Molecular Function	GO:0005515	protein binding	CTBP1	IPI	UniProtKB:Q14526	Human	PMID:16762039
Molecular Function	GO:0005515	protein binding	CTBP1	IPI	UniProtKB:P48552	Human	PMID:17085477
Molecular Function	GO:0005515	protein binding	CTBP1	IPI	UniProtKB:Q8N895	Human	PMID:17085477
Molecular Function	GO:0005515	protein binding	CTBP1	IPI	UniProtKB:Q14526	Human	PMID:19486893
Molecular Function	GO:0005515	protein binding	CTBP1	IPI	UniProtKB:Q01664	Human	PMID:19505873
Molecular Function	GO:0005515	protein binding	CTBP1	IPI	UniProtKB:O43474	Human	PMID:19751731
Molecular Function	GO:0005515	protein binding	CTBP1	IPI	UniProtKB:O00257	Human	PMID:20098713
Molecular Function	GO:0005515	protein binding	CTBP1	IPI	UniProtKB:Q96JN0	Human	PMID:20211142
Molecular Function	GO:0005515	protein binding	CTBP1	IPI	UniProtKB:Q9NYB0	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	CTBP1	IPI	UniProtKB:Q8N3X6	Human	PMID:21900206
Molecular Function	GO:0005515	protein binding	CTBP1	IPI	UniProtKB:A2APF7	Human	PMID:21903422
Molecular Function	GO:0005515	protein binding	CTBP1	IPI	UniProtKB:P56545	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	CTBP1	IPI	UniProtKB:Q96EK4	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	CTBP1	IPI	UniProtKB:Q9BXL5	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	CTBP1	IPI	UniProtKB:Q8NDZ2	Human	PMID:23707407
Molecular Function	GO:0005515	protein binding	CTBP1	IPI	UniProtKB:P48552	Human	PMID:24722188
Molecular Function	GO:0005515	protein binding	CTBP1	IPI	UniProtKB:Q9Y5P3	Human	PMID:24722188
Molecular Function	GO:0005515	protein binding	CTBP1	IPI	UniProtKB:Q8N3X6	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	CTBP1	IPI	UniProtKB:C9JLW8	Human	PMID:25728771
Molecular Function	GO:0005515	protein binding	CTBP1	IPI	UniProtKB:P56545	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CTBP1	IPI	UniProtKB:Q96JN0	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	CTBP1	IPI	UniProtKB:O00257	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CTBP1	IPI	UniProtKB:Q8N3X6	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CTBP1	IPI	UniProtKB:Q92618	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CTBP1	IPI	UniProtKB:Q96JN0	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CTBP1	IPI	UniProtKB:P56545	Human	PMID:28947780
Molecular Function	GO:0005515	protein binding	CTBP1	IPI	UniProtKB:Q92618	Human	PMID:28947780
Molecular Function	GO:0005515	protein binding	CTBP1	IPI	UniProtKB:P56545	Human	PMID:31041561
Molecular Function	GO:0005515	protein binding	CTBP1	IPI	UniProtKB:Q8N3X6	Human	PMID:31041561
Molecular Function	GO:0005515	protein binding	CTBP1	IPI	UniProtKB:Q92618	Human	PMID:31041561
Molecular Function	GO:0005515	protein binding	CTBP1	IPI	UniProtKB:Q96EK4	Human	PMID:31041561
Molecular Function	GO:0005515	protein binding	CTBP1	IPI	UniProtKB:Q96JN0	Human	PMID:31041561
Molecular Function	GO:0005515	protein binding	CTBP1	IPI	UniProtKB:P56545	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CTBP1	IPI	UniProtKB:P48552	Human	PMID:35016035
Molecular Function	GO:0005515	protein binding	CTBP1	IPI	UniProtKB:P56545	Human	PMID:35016035
Molecular Function	GO:0005515	protein binding	CTBP1	IPI	UniProtKB:Q8N3X6	Human	PMID:35016035
Molecular Function	GO:0005515	protein binding	CTBP1	IPI	UniProtKB:Q92618	Human	PMID:35016035
Molecular Function	GO:0005515	protein binding	CTBP1	IPI	UniProtKB:Q96JN0	Human	PMID:35016035
Molecular Function	GO:0005515	protein binding	CTBP1	IPI	UniProtKB:Q9Y5P3	Human	PMID:35016035
Molecular Function	GO:0005515	protein binding	Ctbp1	IPI	UniProtKB:P48552	Mouse	MGI:MGI:3688378|PMID:14736873
Molecular Function	GO:0005515	protein binding	Ctbp1	IPI	UniProtKB:Q14526	Mouse	MGI:MGI:5315366|PMID:12052894
Molecular Function	GO:0005515	protein binding	Ctbp1	IPI	UniProtKB:Q14526	Mouse	MGI:MGI:5306305|PMID:16762039
Molecular Function	GO:0005515	protein binding	Ctbp1	IPI	UniProtKB:O88286	Mouse	MGI:MGI:3690291|PMID:16702210
Molecular Function	GO:0005515	protein binding	Ctbp1	IPI	UniProtKB:Q64318	Mouse	MGI:MGI:4939879|PMID:21224849
Molecular Function	GO:0005515	protein binding	Ctbp1	IPI	UniProtKB:Q14526	Mouse	MGI:MGI:3701023|PMID:16724116
Molecular Function	GO:0005515	protein binding	Ctbp1	IPI	PR:Q99N13	Mouse	PMID:11390982
Molecular Function	GO:0005515	protein binding	Ctbp1	IPI	PR:Q6ZQ88	Mouse	PMID:17392792
Molecular Function	GO:0005515	protein binding	Ctbp1	IPI	UniProtKB:Q9IMY0	Rat	PMID:12372828|RGD:1298829
Molecular Function	GO:0005515	protein binding	Ctbp1	IPI	UniProtKB:O75362	Rat	PMID:16940172|RGD:8553967
Molecular Function	GO:0005515	protein binding	Ctbp1	IPI	UniProtKB:O88778	Rat	PMID:25652077|RGD:11079187
Molecular Function	GO:0005515	protein binding	Ctbp1	IPI	UniProtKB:Q9JKS6	Rat	PMID:25652077|RGD:11079187
Molecular Function	GO:0019904	protein domain specific binding	CTBP1	IPI	UniProtKB:O60907	Human	PMID:18374649
Molecular Function	GO:0019904	protein domain specific binding	CTBP1	IDA		Human	PMID:19162039
Molecular Function	GO:0042803	protein homodimerization activity	Ctbp1	IPI	UniProtKB:Q9Z2F5	Rat	PMID:19351597|RGD:8553313
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	Ctbp1	IPI	UniProtKB:P58462|UniProtKB:P58463	Mouse	MGI:MGI:3606794|PMID:14701752
Molecular Function	GO:0003714	transcription corepressor activity	CTBP1	IDA		Human	PMID:16287852
Molecular Function	GO:0003714	transcription corepressor activity	CTBP1	IDA		Human	PMID:19162039
Molecular Function	GO:0001222	transcription corepressor binding	CTBP1	IPI	UniProtKB:Q96JN0	Human	PMID:29628311
Cellular Component	GO:0005737	cytoplasm	Ctbp1	IMP		Rat	PMID:11590170|RGD:12793005
Cellular Component	GO:0098894	extrinsic component of presynaptic endocytic zone membrane	Ctbp1	IDA		Rat	PMID:32075774|RGD:155230742
Cellular Component	GO:0098982	GABA-ergic synapse	Ctbp1	IDA		Mouse	PMID:22745816
Cellular Component	GO:0098978	glutamatergic synapse	Ctbp1	IDA		Mouse	PMID:22745816
Cellular Component	GO:0098978	glutamatergic synapse	Ctbp1	IDA		Mouse	PMID:32075774
Cellular Component	GO:0098978	glutamatergic synapse	Ctbp1	IMP		Mouse	PMID:32075774
Cellular Component	GO:0098978	glutamatergic synapse	Ctbp1	IDA		Rat	PMID:25652077|RGD:11079187
Cellular Component	GO:0098978	glutamatergic synapse	Ctbp1	IMP		Rat	PMID:25652077|RGD:11079187
Cellular Component	GO:0005654	nucleoplasm	CTBP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	CTBP1	IDA		Human	PMID:16702210
Cellular Component	GO:0005634	nucleus	Ctbp1	IDA		Mouse	MGI:MGI:3690291|PMID:16702210
Cellular Component	GO:0005634	nucleus	Ctbp1	IDA		Mouse	MGI:MGI:4365360|PMID:18483224
Cellular Component	GO:0005634	nucleus	Ctbp1	IMP		Rat	PMID:11590170|RGD:12793005
Cellular Component	GO:0005634	nucleus	Ctbp1	IDA		Rat	PMID:25652077|RGD:11079187
Cellular Component	GO:0098793	presynapse	Ctbp1	IDA		Rat	PMID:25652077|RGD:11079187
Cellular Component	GO:0098831	presynaptic active zone cytoplasmic component	Ctbp1	IDA		Mouse	PMID:22745816
Cellular Component	GO:0017053	transcription repressor complex	CTBP1	IDA		Human	PMID:16287852
Cellular Component	GO:0017053	transcription repressor complex	CTBP1	IDA		Human	PMID:19162039
Cellular Component	GO:0017053	transcription repressor complex	Ctbp1	IDA		Mouse	MGI:MGI:4365360|PMID:18483224
Biological Process	GO:0031507	heterochromatin formation	CTBP1	IMP		Human	PMID:21102443
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Ctbp1	IDA		Mouse	MGI:MGI:4365360|PMID:18483224
Biological Process	GO:0035067	negative regulation of histone acetylation	CTBP1	IMP		Human	PMID:21102443
Biological Process	GO:0090241	negative regulation of histone H4 acetylation	CTBP1	IMP		Human	PMID:21102443
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	CTBP1	IMP		Human	PMID:19162039
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	CTBP1	IMP		Human	PMID:21102443
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Ctbp1	IMP		Mouse	PMID:17392792
Biological Process	GO:0031065	positive regulation of histone deacetylation	CTBP1	IMP		Human	PMID:21102443
Biological Process	GO:0099526	presynapse to nucleus signaling pathway	Ctbp1	IDA		Rat	PMID:25652077|RGD:11079187
Biological Process	GO:0099526	presynapse to nucleus signaling pathway	Ctbp1	IMP		Rat	PMID:25652077|RGD:11079187
Biological Process	GO:0051726	regulation of cell cycle	CTBP1	IMP		Human	PMID:21102443
Biological Process	GO:0048384	retinoic acid receptor signaling pathway	ctbp1	IGI	ZFIN:ZDB-GENO-090916-1,ZFIN:ZDB-MRPHLNO-070121-2	Zfish	PMID:20850014
Biological Process	GO:0097091	synaptic vesicle clustering	Ctbp1	IMP		Mouse	PMID:32075774
Biological Process	GO:0097091	synaptic vesicle clustering	Ctbp1	IDA		Mouse	PMID:32075774
Biological Process	GO:0048488	synaptic vesicle endocytosis	Ctbp1	IMP		Mouse	PMID:32075774
Biological Process	GO:0048488	synaptic vesicle endocytosis	Ctbp1	IDA		Mouse	PMID:32075774
Biological Process	GO:0050872	white fat cell differentiation	Ctbp1	IDA		Mouse	MGI:MGI:4365360|PMID:18483224

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern