Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CTBP2
  • Mouse genes Ctbp2
  • Rat genes Ctbp2
  • Zfish genes ctbp2a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ctbp2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Ctbp2	IDA		Mouse	PMID:23775127
Molecular Function	GO:0042974	nuclear retinoic acid receptor binding	Ctbp2	IPI	PR:P28700	Mouse	PMID:23775127
Molecular Function	GO:0005515	protein binding	CTBP2	IPI	UniProtKB:Q15583	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	CTBP2	IPI	UniProtKB:Q9Y5P3	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	CTBP2	IPI	UniProtKB:O95785	Human	PMID:16702210
Molecular Function	GO:0005515	protein binding	CTBP2	IPI	UniProtKB:Q14526	Human	PMID:19486893
Molecular Function	GO:0005515	protein binding	CTBP2	IPI	UniProtKB:Q13422	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	CTBP2	IPI	UniProtKB:Q15583	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	CTBP2	IPI	UniProtKB:O15409	Human	PMID:21653829
Molecular Function	GO:0005515	protein binding	CTBP2	IPI	UniProtKB:A2APF7	Human	PMID:21903422
Molecular Function	GO:0005515	protein binding	CTBP2	IPI	UniProtKB:O75807	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	CTBP2	IPI	UniProtKB:P20749	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	CTBP2	IPI	UniProtKB:P51946	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	CTBP2	IPI	UniProtKB:Q13363	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	CTBP2	IPI	UniProtKB:Q92786	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	CTBP2	IPI	UniProtKB:Q9UN79	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	CTBP2	IPI	UniProtKB:O15409	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CTBP2	IPI	UniProtKB:O94818-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CTBP2	IPI	UniProtKB:Q13363-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CTBP2	IPI	UniProtKB:Q13422	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CTBP2	IPI	UniProtKB:Q15583	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CTBP2	IPI	UniProtKB:Q32MQ0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CTBP2	IPI	UniProtKB:Q8IVP5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CTBP2	IPI	UniProtKB:Q96JN0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CTBP2	IPI	UniProtKB:Q96MY1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CTBP2	IPI	UniProtKB:Q9NQ66	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CTBP2	IPI	UniProtKB:Q9UKS7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CTBP2	IPI	UniProtKB:Q9Y5P3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CTBP2	IPI	UniProtKB:C9JLW8	Human	PMID:25728771
Molecular Function	GO:0005515	protein binding	CTBP2	IPI	UniProtKB:Q15583-2	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	CTBP2	IPI	UniProtKB:Q13363	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CTBP2	IPI	UniProtKB:A0A0S2Z5I3	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	CTBP2	IPI	UniProtKB:Q13363-2	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	CTBP2	IPI	UniProtKB:Q13643	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	CTBP2	IPI	UniProtKB:Q96JN0	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	CTBP2	IPI	UniProtKB:Q13363	Human	PMID:28947780
Molecular Function	GO:0005515	protein binding	CTBP2	IPI	UniProtKB:Q92618	Human	PMID:28947780
Molecular Function	GO:0005515	protein binding	CTBP2	IPI	UniProtKB:Q13363	Human	PMID:31041561
Molecular Function	GO:0005515	protein binding	CTBP2	IPI	UniProtKB:Q13363	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CTBP2	IPI	UniProtKB:Q96JN0	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	CTBP2	IPI	UniProtKB:Q13363	Human	PMID:35016035
Molecular Function	GO:0005515	protein binding	CTBP2	IPI	UniProtKB:Q99592	Human	PMID:35800763
Molecular Function	GO:0005515	protein binding	Ctbp2	IPI	UniProtKB:O75362	Mouse	MGI:MGI:3689671|PMID:16940172
Molecular Function	GO:0005515	protein binding	Ctbp2	IPI	UniProtKB:O88286	Mouse	MGI:MGI:3690291|PMID:16702210
Molecular Function	GO:0005515	protein binding	Ctbp2	IPI	UniProtKB:Q03112	Mouse	MGI:MGI:4418632|PMID:11328817
Molecular Function	GO:0005515	protein binding	Ctbp2	IPI	UniProtKB:Q8CCH7	Mouse	MGI:MGI:5009348|PMID:20705609
Molecular Function	GO:0005515	protein binding	Ctbp2	IPI	UniProtKB:P48552	Mouse	MGI:MGI:3688378|PMID:14736873
Molecular Function	GO:0005515	protein binding	Ctbp2	IPI	UniProtKB:Q9HAZ2-2|UniProtKB:Q9HAZ2-4	Mouse	MGI:MGI:5318006|PMID:21516122
Molecular Function	GO:0005515	protein binding	Ctbp2	IPI	UniProtKB:Q14526	Mouse	MGI:MGI:5306305|PMID:16762039
Molecular Function	GO:0005515	protein binding	Ctbp2	IPI	UniProtKB:Q03112	Mouse	MGI:MGI:4839443|PMID:17635584
Molecular Function	GO:0005515	protein binding	Ctbp2	IPI	PR:O35615	Mouse	PMID:11940669
Molecular Function	GO:0005515	protein binding	Ctbp2	IPI	PR:Q925H1	Mouse	PMID:12444977
Molecular Function	GO:0019901	protein kinase binding	CTBP2	IPI	UniProtKB:Q9H2X6	Human	PMID:23393140
Molecular Function	GO:0044877	protein-containing complex binding	CTBP2	IPI	UniProtKB:P50613,UniProtKB:P51946	Human	PMID:23393140
Molecular Function	GO:0098882	structural constituent of presynaptic active zone	Ctbp2	IDA		Mouse	PMID:26929012
Molecular Function	GO:0098882	structural constituent of presynaptic active zone	Ctbp2	IMP		Mouse	PMID:26929012
Molecular Function	GO:0003713	transcription coactivator activity	Ctbp2	IGI	MGI:MGI:98214	Mouse	PMID:23775127
Molecular Function	GO:0001221	transcription coregulator binding	Ctbp2	IPI	UniProtKB:Q8WW38	Mouse	MGI:MGI:1342875|PMID:10438528
Molecular Function	GO:0003714	transcription corepressor activity	Ctbp2	IPI	UniProtKB:Q9Z2Z2	Mouse	PMID:12444977
Molecular Function	GO:0003714	transcription corepressor activity	Ctbp2	IPI	PR:Q925H1	Mouse	PMID:12444977
Molecular Function	GO:0003714	transcription corepressor activity	Ctbp2	IPI	PR:Q03267	Mouse	PMID:12444977
Molecular Function	GO:0003714	transcription corepressor activity	Ctbp2	IDA		Mouse	PMID:10567582
Molecular Function	GO:0001222	transcription corepressor binding	CTBP2	IPI	UniProtKB:Q96JN0	Human	PMID:29628311
Cellular Component	GO:0098982	GABA-ergic synapse	Ctbp2	IDA		Mouse	PMID:22745816
Cellular Component	GO:0098978	glutamatergic synapse	Ctbp2	IDA		Mouse	PMID:15728193
Cellular Component	GO:0098978	glutamatergic synapse	Ctbp2	IDA		Mouse	PMID:26929012
Cellular Component	GO:0098978	glutamatergic synapse	Ctbp2	IMP		Mouse	PMID:26929012
Cellular Component	GO:0098978	glutamatergic synapse	Ctbp2	IDA		Mouse	PMID:22745816
Cellular Component	GO:0005634	nucleus	CTBP2	IDA		Human	PMID:16702210
Cellular Component	GO:0005634	nucleus	Ctbp2	IDA		Mouse	MGI:MGI:4365360|PMID:18483224
Cellular Component	GO:0005634	nucleus	Ctbp2	IDA		Mouse	MGI:MGI:3690291|PMID:16702210
Cellular Component	GO:0098684	photoreceptor ribbon synapse	Ctbp2	IDA		Mouse	PMID:15728193
Cellular Component	GO:0098684	photoreceptor ribbon synapse	Ctbp2	IDA		Mouse	PMID:26929012
Cellular Component	GO:0098684	photoreceptor ribbon synapse	Ctbp2	IMP		Mouse	PMID:26929012
Cellular Component	GO:0098831	presynaptic active zone cytoplasmic component	Ctbp2	IDA		Mouse	PMID:15728193
Cellular Component	GO:0098831	presynaptic active zone cytoplasmic component	Ctbp2	IDA		Mouse	PMID:22745816
Cellular Component	GO:0099523	presynaptic cytosol	Ctbp2	IDA		Mouse	PMID:22745816
Cellular Component	GO:0097470	ribbon synapse	Ctbp2	IDA		Mouse	PMID:19932743
Cellular Component	GO:0045202	synapse	Ctbp2	IDA		Mouse	PMID:20368623
Cellular Component	GO:0017053	transcription repressor complex	Ctbp2	IDA		Mouse	MGI:MGI:4365360|PMID:18483224
Biological Process	GO:0043010	camera-type eye development	ctbp2a	IMP	ZFIN:ZDB-MRPHLNO-050902-4	Zfish	PMID:15673675
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	Ctbp2	IEP		Mouse	PMID:20439489
Biological Process	GO:0070073	clustering of voltage-gated calcium channels	ctbp2a	IGI	ZFIN:ZDB-MRPHLNO-050902-4,ZFIN:ZDB-MRPHLNO-110325-2	Zfish	PMID:21350006
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Ctbp2	IDA		Mouse	MGI:MGI:4365360|PMID:18483224
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Ctbp2	IPI	UniProtKB:O03267	Mouse	PMID:12444977
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Ctbp2	IPI	UniProtKB:Q9Z2Z2	Mouse	PMID:12444977
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Ctbp2	IPI	PR:Q925H1	Mouse	PMID:12444977
Biological Process	GO:0035563	positive regulation of chromatin binding	Ctbp2	IMP		Mouse	PMID:23775127
Biological Process	GO:0048386	positive regulation of retinoic acid receptor signaling pathway	CTBP2	IMP		Human	PMID:23775127
Biological Process	GO:0048386	positive regulation of retinoic acid receptor signaling pathway	Ctbp2	IMP		Mouse	PMID:23775127
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	CTBP2	IMP		Human	PMID:23775127
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ctbp2	IGI	MGI:MGI:98214	Mouse	PMID:23775127
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ctbp2	IMP		Mouse	PMID:23775127
Biological Process	GO:0014013	regulation of gliogenesis	ctbp2a	IMP	ZFIN:ZDB-MRPHLNO-141121-7	Zfish	PMID:25132384
Biological Process	GO:0014013	regulation of gliogenesis	ctbp2a	IGI	ZFIN:ZDB-GENE-081203-18	Zfish	PMID:25132384
Biological Process	GO:0014013	regulation of gliogenesis	ctbp2a	IMP	ZFIN:ZDB-MRPHLNO-141201-1	Zfish	PMID:25132384
Biological Process	GO:0045634	regulation of melanocyte differentiation	ctbp2a	IMP	ZFIN:ZDB-MRPHLNO-110331-1	Zfish	PMID:21199918
Biological Process	GO:0045634	regulation of melanocyte differentiation	ctbp2a	IMP	ZFIN:ZDB-MRPHLNO-110331-2	Zfish	PMID:21199918
Biological Process	GO:0007416	synapse assembly	ctbp2a	IMP	ZFIN:ZDB-MRPHLNO-050902-4	Zfish	PMID:15673675
Biological Process	GO:0060386	synapse assembly involved in innervation	ctbp2a	IGI	ZFIN:ZDB-MRPHLNO-050902-4,ZFIN:ZDB-MRPHLNO-110325-2	Zfish	PMID:21350006
Biological Process	GO:0016081	synaptic vesicle docking	Ctbp2	IDA		Mouse	PMID:26929012
Biological Process	GO:0016081	synaptic vesicle docking	Ctbp2	IMP		Mouse	PMID:26929012
Biological Process	GO:0050872	white fat cell differentiation	Ctbp2	IDA		Mouse	MGI:MGI:4365360|PMID:18483224

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern