Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CTCFL
  • Mouse genes Ctcfl
  • Rat genes Ctcfl
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ctcfl

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	CTCFL	IDA		Human	PMID:18413740
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	CTCFL	IDA		Human	PMID:16140944
Molecular Function	GO:0042393	histone binding	Ctcfl	IDA		Mouse	MGI:MGI:3692841|PMID:17048991
Molecular Function	GO:0005515	protein binding	CTCFL	IPI	UniProtKB:O15047	Human	PMID:18765639
Molecular Function	GO:0005515	protein binding	CTCFL	IPI	UniProtKB:P46379	Human	PMID:18765639
Molecular Function	GO:0005515	protein binding	Ctcfl	IPI	UniProtKB:Q922X9	Mouse	MGI:MGI:3692841|PMID:17048991
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	CTCFL	IDA		Human	PMID:16140944
Molecular Function	GO:0043565	sequence-specific DNA binding	CTCFL	IDA		Human	PMID:18765639
Molecular Function	GO:0043565	sequence-specific DNA binding	Ctcfl	IDA		Mouse	MGI:MGI:3692841|PMID:17048991
Molecular Function	GO:0000976	transcription cis-regulatory region binding	CTCFL	IDA		Human	PMID:18413740
Cellular Component	GO:0005737	cytoplasm	Ctcfl	IDA		Mouse	PMID:12011441
Cellular Component	GO:0005829	cytosol	CTCFL	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016604	nuclear body	CTCFL	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	CTCFL	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Ctcfl	IDA		Mouse	MGI:MGI:3692841|PMID:17048991
Biological Process	GO:0071169	establishment of protein localization to chromatin	CTCFL	IMP		Human	PMID:18765639
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	CTCFL	IDA		Human	PMID:18413740
Biological Process	GO:0010628	positive regulation of gene expression	CTCFL	IDA		Human	PMID:18413740
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	CTCFL	IDA		Human	PMID:16140944
Biological Process	GO:0006349	regulation of gene expression by genomic imprinting	Ctcfl	IDA		Mouse	MGI:MGI:3692841|PMID:17048991
Biological Process	GO:0045815	transcription initiation-coupled chromatin remodeling	CTCFL	IMP		Human	PMID:18765639

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern