Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Ctnna1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes CTNNA1
- Mouse genes Ctnna1
- Rat genes Ctnna1
- Zfish genes ctnna1
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ctnna1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051015	actin filament binding	Ctnna1	IDA		Mouse	PMID:11795944
Molecular Function	GO:0051015	actin filament binding	ctnna1	IDA		Zfish	PMID:23788645
Molecular Function	GO:0008013	beta-catenin binding	CTNNA1	IPI	UniProtKB:P35222	Human	PMID:7650039
Molecular Function	GO:0008013	beta-catenin binding	CTNNA1	IPI	UniProtKB:P35222	Human	PMID:7890674
Molecular Function	GO:0008013	beta-catenin binding	Ctnna1	IPI	RGD:70487	Rat	PMID:12960056\|RGD:150530287
Molecular Function	GO:0045296	cadherin binding	CTNNA1	IPI	UniProtKB:Q86UP0-1	Human	PMID:12734196
Molecular Function	GO:0045296	cadherin binding	CTNNA1	IPI	UniProtKB:Q86UP0-2	Human	PMID:12734196
Molecular Function	GO:0045296	cadherin binding	CTNNA1	HDA		Human	PMID:25468996
Molecular Function	GO:0045296	cadherin binding	CTNNA1	IPI	UniProtKB:P19022	Human	PMID:7650039
Molecular Function	GO:0045296	cadherin binding	ctnna1	IDA		Zfish	PMID:10456847
Molecular Function	GO:0045295	gamma-catenin binding	CTNNA1	IPI	UniProtKB:P14923	Human	PMID:7650039
Molecular Function	GO:0045295	gamma-catenin binding	CTNNA1	IPI	UniProtKB:P14923	Human	PMID:7890674
Molecular Function	GO:0042802	identical protein binding	CTNNA1	IPI	UniProtKB:P35221	Human	PMID:23292143
Molecular Function	GO:0042802	identical protein binding	Ctnna1	IPI	UniProtKB:P26231	Mouse	MGI:MGI:5476862\|PMID:23417122
Molecular Function	GO:0005515	protein binding	CTNNA1	IPI	UniProtKB:Q96KN1	Human	PMID:12477722
Molecular Function	GO:0005515	protein binding	CTNNA1	IPI	UniProtKB:P12830	Human	PMID:16212417
Molecular Function	GO:0005515	protein binding	CTNNA1	IPI	UniProtKB:P35222	Human	PMID:17052462
Molecular Function	GO:0005515	protein binding	CTNNA1	IPI	UniProtKB:P35222	Human	PMID:17098867
Molecular Function	GO:0005515	protein binding	CTNNA1	IPI	UniProtKB:Q9ERG0-2	Human	PMID:18093941
Molecular Function	GO:0005515	protein binding	CTNNA1	IPI	UniProtKB:Q9UHB6	Human	PMID:18093941
Molecular Function	GO:0005515	protein binding	CTNNA1	IPI	UniProtKB:P12830	Human	PMID:19016843
Molecular Function	GO:0005515	protein binding	CTNNA1	IPI	UniProtKB:P25054	Human	PMID:20936779
Molecular Function	GO:0005515	protein binding	CTNNA1	IPI	UniProtKB:P12830	Human	PMID:22750944
Molecular Function	GO:0005515	protein binding	CTNNA1	IPI	UniProtKB:Q9H0H5	Human	PMID:22750944
Molecular Function	GO:0005515	protein binding	CTNNA1	IPI	UniProtKB:Q9H8V3	Human	PMID:22750944
Molecular Function	GO:0005515	protein binding	CTNNA1	IPI	UniProtKB:P18206-2	Human	PMID:23292143
Molecular Function	GO:0005515	protein binding	CTNNA1	IPI	UniProtKB:P25963	Human	PMID:24509793
Molecular Function	GO:0005515	protein binding	CTNNA1	IPI	UniProtKB:P35222	Human	PMID:24509793
Molecular Function	GO:0005515	protein binding	CTNNA1	IPI	UniProtKB:P25054	Human	PMID:25241761
Molecular Function	GO:0005515	protein binding	CTNNA1	IPI	UniProtKB:Q5VT06	Human	PMID:25764135
Molecular Function	GO:0005515	protein binding	CTNNA1	IPI	UniProtKB:P25054	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CTNNA1	IPI	UniProtKB:P35222	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	CTNNA1	IPI	UniProtKB:O60716,UniProtKB:P35222,UniProtKB:Q8IXH8	Human	PMID:28051089
Molecular Function	GO:0005515	protein binding	CTNNA1	IPI	UniProtKB:P12830	Human	PMID:34591612
Molecular Function	GO:0005515	protein binding	Ctnna1	IPI	UniProtKB:Q02248	Mouse	MGI:MGI:1355058\|PMID:10882138
Molecular Function	GO:0005515	protein binding	Ctnna1	IPI	UniProtKB:P35222\|UniProtKB:Q02248	Mouse	MGI:MGI:5318039\|PMID:9264463
Molecular Function	GO:0005515	protein binding	Ctnna1	IPI	UniProtKB:O35889	Mouse	MGI:MGI:5532921\|PMID:10974003
Molecular Function	GO:0005515	protein binding	Ctnna1	IPI	PR:Q05860	Mouse	PMID:14647292
Molecular Function	GO:0005515	protein binding	Ctnna1	IPI	PR:Q02257	Mouse	PMID:14579029
Molecular Function	GO:0005515	protein binding	Ctnna1	IPI	PR:Q02248	Mouse	PMID:8853988
Molecular Function	GO:0005515	protein binding	Ctnna1	IPI	RGD:70487	Rat	PMID:12640114\|RGD:2289806
Molecular Function	GO:0044877	protein-containing complex binding	Ctnna1	IPI	RGD:69280\|RGD:620412	Rat	PMID:8834786\|RGD:2291902
Molecular Function	GO:0044877	protein-containing complex binding	Ctnna1	IPI	RGD:69280\|RGD:70487	Rat	PMID:8834786\|RGD:2291902
Molecular Function	GO:0003723	RNA binding	CTNNA1	HDA		Human	PMID:22658674
Molecular Function	GO:0017166	vinculin binding	CTNNA1	IPI	UniProtKB:P18206	Human	PMID:9700171
Cellular Component	GO:0001669	acrosomal vesicle	Ctnna1	IDA		Rat	PMID:16755864\|RGD:2289801
Cellular Component	GO:0005912	adherens junction	Ctnna1	IDA		Mouse	PMID:12695331
Cellular Component	GO:0005912	adherens junction	Ctnna1	IDA		Mouse	PMID:19129494
Cellular Component	GO:0005912	adherens junction	Ctnna1	IDA		Mouse	PMID:15775979
Cellular Component	GO:0005912	adherens junction	Ctnna1	IDA		Rat	PMID:8834786\|RGD:2291902
Cellular Component	GO:0005912	adherens junction	ctnna1	IDA		Zfish	PMID:10456847
Cellular Component	GO:0016342	catenin complex	CTNNA1	IDA		Human	PMID:28051089
Cellular Component	GO:0016342	catenin complex	CTNNA1	IDA		Human	PMID:7650039
Cellular Component	GO:0016342	catenin complex	ctnna1	IDA		Zfish	PMID:10456847
Cellular Component	GO:0005938	cell cortex	ctnna1	IDA		Zfish	PMID:10456847
Cellular Component	GO:0030054	cell junction	CTNNA1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005911	cell-cell junction	CTNNA1	IDA		Human	PMID:10460003
Cellular Component	GO:0005911	cell-cell junction	CTNNA1	IDA		Human	PMID:7650039
Cellular Component	GO:0005911	cell-cell junction	Ctnna1	IDA		Rat	PMID:15197645\|RGD:2289803
Cellular Component	GO:0005737	cytoplasm	Ctnna1	IDA		Rat	PMID:16755864\|RGD:2289801
Cellular Component	GO:0016600	flotillin complex	Ctnna1	IDA		Mouse	MGI:MGI:5634880\|PMID:24046456
Cellular Component	GO:0005925	focal adhesion	CTNNA1	HDA		Human	PMID:21423176
Cellular Component	GO:0014704	intercalated disc	Ctnna1	IDA		Mouse	PMID:17535849
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	CTNNA1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0030027	lamellipodium	Ctnna1	IDA		Mouse	PMID:14657280
Cellular Component	GO:0005902	microvillus	ctnna1	IDA		Zfish	PMID:10456847
Cellular Component	GO:0005886	plasma membrane	CTNNA1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Ctnna1	IDA		Mouse	PMID:8853988
Cellular Component	GO:0005886	plasma membrane	Ctnna1	IDA		Rat	PMID:17899156\|RGD:2289800
Cellular Component	GO:0005915	zonula adherens	Ctnna1	IDA		Mouse	PMID:11025210
Biological Process	GO:0007568	aging	Ctnna1	IEP		Rat	PMID:15178134\|RGD:2289805
Biological Process	GO:0043297	apical junction assembly	Ctnna1	IMP	MGI:MGI:2176173,MGI:MGI:2677796	Mouse	PMID:16543460
Biological Process	GO:0043297	apical junction assembly	Ctnna1	IMP	MGI:MGI:2677796	Mouse	PMID:22411810
Biological Process	GO:0006915	apoptotic process	Ctnna1	IMP	MGI:MGI:2176173,MGI:MGI:2677796	Mouse	PMID:16543460
Biological Process	GO:0031103	axon regeneration	Ctnna1	IEP		Rat	PMID:12387456\|RGD:632464
Biological Process	GO:0048870	cell motility	Ctnna1	IMP	MGI:MGI:2677796	Mouse	PMID:22411810
Biological Process	GO:0071681	cellular response to indole-3-methanol	CTNNA1	IDA		Human	PMID:10868478
Biological Process	GO:0090136	epithelial cell-cell adhesion	Ctnna1	IMP	MGI:MGI:2677796	Mouse	PMID:22411810
Biological Process	GO:0007163	establishment or maintenance of cell polarity	Ctnna1	IMP	MGI:MGI:2176173,MGI:MGI:2677796	Mouse	PMID:16543460
Biological Process	GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand	Ctnna1	IMP	MGI:MGI:2677796	Mouse	PMID:22411810
Biological Process	GO:0016264	gap junction assembly	Ctnna1	IMP		Rat	PMID:12577316\|RGD:2289808
Biological Process	GO:0007229	integrin-mediated signaling pathway	Ctnna1	IMP	MGI:MGI:2677796	Mouse	PMID:22411810
Biological Process	GO:0008584	male gonad development	Ctnna1	IEP		Rat	PMID:7507830\|RGD:2289812
Biological Process	GO:0043066	negative regulation of apoptotic process	Ctnna1	IMP	MGI:MGI:2176173,MGI:MGI:2677796	Mouse	PMID:16543460
Biological Process	GO:2000146	negative regulation of cell motility	Ctnna1	IMP	MGI:MGI:2677796	Mouse	PMID:22411810
Biological Process	GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	Ctnna1	IMP	MGI:MGI:2677796	Mouse	PMID:22411810
Biological Process	GO:2001045	negative regulation of integrin-mediated signaling pathway	Ctnna1	IMP	MGI:MGI:2677796	Mouse	PMID:22411810
Biological Process	GO:0007406	negative regulation of neuroblast proliferation	Ctnna1	IMP	MGI:MGI:2176173,MGI:MGI:2677796	Mouse	PMID:16543460
Biological Process	GO:0007406	negative regulation of neuroblast proliferation	Ctnna1	IGI	MGI:MGI:108075	Mouse	PMID:16543460
Biological Process	GO:1900181	negative regulation of protein localization to nucleus	Ctnna1	IMP		Mouse	MGI:MGI:4939579\|PMID:21145499
Biological Process	GO:0007405	neuroblast proliferation	Ctnna1	IMP	MGI:MGI:2176173,MGI:MGI:2677796	Mouse	PMID:16543460
Biological Process	GO:0007405	neuroblast proliferation	Ctnna1	IGI	MGI:MGI:108075	Mouse	PMID:16543460
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	Ctnna1	IEP		Rat	PMID:10681393\|RGD:2289810
Biological Process	GO:0001541	ovarian follicle development	Ctnna1	IEP		Rat	PMID:10864803\|RGD:2289809
Biological Process	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand	Ctnna1	IMP	MGI:MGI:2677796	Mouse	PMID:22411810
Biological Process	GO:0045880	positive regulation of smoothened signaling pathway	Ctnna1	IGI	MGI:MGI:108075	Mouse	PMID:16543460
Biological Process	GO:0008104	protein localization	Ctnna1	IMP	MGI:MGI:2677796	Mouse	PMID:22411810
Biological Process	GO:0042127	regulation of cell population proliferation	Ctnna1	IGI	MGI:MGI:88039	Mouse	PMID:17989230
Biological Process	GO:0043627	response to estrogen	Ctnna1	IEP		Rat	PMID:10864803\|RGD:2289809
Biological Process	GO:0014070	response to organic cyclic compound	Ctnna1	IEP		Rat	PMID:16678996\|RGD:2289802
Biological Process	GO:0007224	smoothened signaling pathway	Ctnna1	IGI	MGI:MGI:108075	Mouse	PMID:16543460
Biological Process	GO:0001894	tissue homeostasis	ctnna1	IMP	ZFIN:ZDB-GENO-170124-1	Zfish	PMID:27612508

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.