Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CTSA
  • Mouse genes Ctsa
  • Rat genes Ctsa
  • Zfish genes ctsa
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ctsa

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Ctsa	IPI	PR:O35657	Mouse	PMID:9425240
Molecular Function	GO:0004185	serine-type carboxypeptidase activity	CTSA	IMP		Human	PMID:12505983
Molecular Function	GO:0004185	serine-type carboxypeptidase activity	CTSA	IMP		Human	PMID:1907282
Cellular Component	GO:0070062	extracellular exosome	CTSA	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	CTSA	HDA		Human	PMID:23533145
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	CTSA	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	CTSA	HDA		Human	PMID:19946888
Cellular Component	GO:0005739	mitochondrion	Ctsa	HDA		Mouse	PMID:14651853
Biological Process	GO:1904715	negative regulation of chaperone-mediated autophagy	CTSA	IGI	UniProtKB:P10619	Human	PMID:12505983
Biological Process	GO:1904715	negative regulation of chaperone-mediated autophagy	Ctsa	IMP		Mouse	MGI:MGI:5700310|PMID:12505983
Biological Process	GO:0006508	proteolysis	CTSA	IDA		Human	PMID:12505983
Biological Process	GO:0031647	regulation of protein stability	CTSA	IMP		Human	PMID:12505983
Biological Process	GO:0031647	regulation of protein stability	Ctsa	IMP		Mouse	MGI:MGI:5700310|PMID:12505983

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern