Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CTSE
  • Mouse genes Ctse
  • Rat genes Ctse
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ctse

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004190	aspartic-type endopeptidase activity	CTSE	IDA		Human	PMID:7789521
Molecular Function	GO:0004190	aspartic-type endopeptidase activity	Ctse	IDA		Mouse	MGI:MGI:87708|PMID:9180269
Molecular Function	GO:0004190	aspartic-type endopeptidase activity	Ctse	IDA		Rat	PMID:8157122|RGD:8554034
Molecular Function	GO:0042802	identical protein binding	Ctse	IPI	PR:P70269	Mouse	PMID:15100295
Molecular Function	GO:0008233	peptidase activity	CTSE	IDA		Human	PMID:16997486
Cellular Component	GO:0005768	endosome	CTSE	IDA		Human	PMID:7983070
Cellular Component	GO:0005768	endosome	Ctse	IDA		Mouse	MGI:MGI:3690810|PMID:1601038
Cellular Component	GO:0005768	endosome	Ctse	IDA		Rat	PMID:9572291|RGD:8553363
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	CTSE	IDA		Human	GO_REF:0000052
Biological Process	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	CTSE	IDA		Human	PMID:8765029
Biological Process	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	Ctse	IDA		Mouse	MGI:MGI:2158899|PMID:11719510
Biological Process	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	Ctse	IDA		Rat	PMID:8491674|RGD:8553254
Biological Process	GO:0016540	protein autoprocessing	Ctse	IMP		Rat	PMID:16367762|RGD:2325171
Biological Process	GO:0006508	proteolysis	CTSE	IDA		Human	PMID:16997486

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern