Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CUX1
  • Mouse genes Cux1
  • Rat genes Cux1
  • Zfish genes cux1a,cux1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cux1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Cux1	IDA		Mouse	PMID:15994318
Molecular Function	GO:0003677	DNA binding	Cux1	IDA		Mouse	PMID:15656993
Molecular Function	GO:0005515	protein binding	Cux1	IPI	UniProtKB:Q8VI24	Mouse	MGI:MGI:6280169|PMID:30726206
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	Cux1	IPI	RGD:1308163	Rat	PMID:15718469|RGD:1599272
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Cux1	IDA		Mouse	PMID:18836447
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Cux1	IMP		Mouse	MGI:MGI:4836115|PMID:20510857
Molecular Function	GO:0043565	sequence-specific DNA binding	CUX1	IDA		Human	PMID:15656993
Molecular Function	GO:0043565	sequence-specific DNA binding	Cux1	IDA		Mouse	PMID:1363085
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	CUX1	IDA		Human	PMID:28473536
Cellular Component	GO:0005737	cytoplasm	Cux1	IDA		Mouse	PMID:20473291
Cellular Component	GO:0005794	Golgi apparatus	CUX1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0000139	Golgi membrane	Cux1	IDA		Rat	PMID:15718469|RGD:1599272
Cellular Component	GO:0043005	neuron projection	Cux1	IDA		Mouse	PMID:25100583
Cellular Component	GO:0005654	nucleoplasm	CUX1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	CUX1	IDA		Human	PMID:15656993
Cellular Component	GO:0005634	nucleus	Cux1	IDA		Mouse	PMID:11839809
Cellular Component	GO:0005634	nucleus	Cux1	IDA		Mouse	PMID:20473291
Cellular Component	GO:0005634	nucleus	Cux1	IDA		Mouse	PMID:11544187
Cellular Component	GO:0005634	nucleus	Cux1	IDA		Mouse	PMID:1363085
Biological Process	GO:0042491	inner ear auditory receptor cell differentiation	Cux1	IMP	MGI:MGI:2388352	Mouse	PMID:11544187
Biological Process	GO:0001822	kidney development	Cux1	IGI	MGI:MGI:2177632	Mouse	PMID:18829740
Biological Process	GO:0030324	lung development	Cux1	IMP	MGI:MGI:2388352	Mouse	PMID:11544187
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Cux1	IDA		Mouse	PMID:11544187
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Cux1	IDA		Mouse	PMID:1363085
Biological Process	GO:0050775	positive regulation of dendrite morphogenesis	Cux1	IMP		Mouse	MGI:MGI:4836115|PMID:20510857
Biological Process	GO:0000301	retrograde transport, vesicle recycling within Golgi	Cux1	IMP		Rat	PMID:15718469|RGD:1599272

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern