Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CXADR
  • Mouse genes Cxadr
  • Rat genes Cxadr
  • Zfish genes cxadr
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cxadr

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008013	beta-catenin binding	CXADR	IPI	UniProtKB:P35222	Human	PMID:12297051
Molecular Function	GO:0008013	beta-catenin binding	Cxadr	IPI	UniProtKB:Q02248	Mouse	MGI:MGI:3814765|PMID:18636119
Molecular Function	GO:0050839	cell adhesion molecule binding	CXADR	IPI	UniProtKB:Q86YT9	Human	PMID:12869515
Molecular Function	GO:0050839	cell adhesion molecule binding	CXADR	IPI	UniProtKB:Q86YT9	Human	PMID:15800062
Molecular Function	GO:0071253	connexin binding	Cxadr	IPI	UniProtKB:P28229	Mouse	MGI:MGI:3814765|PMID:18636119
Molecular Function	GO:0005178	integrin binding	CXADR	IPI	UniProtKB:P13612	Human	PMID:12869515
Molecular Function	GO:0030165	PDZ domain binding	CXADR	IPI	UniProtKB:O75970	Human	PMID:15364909
Molecular Function	GO:0005515	protein binding	CXADR	IPI	UniProtKB:Q07157	Human	PMID:11734628
Molecular Function	GO:0005515	protein binding	CXADR	IPI	UniProtKB:Q9NP85	Human	PMID:17675666
Molecular Function	GO:0005515	protein binding	CXADR	IPI	UniProtKB:P21145	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CXADR	IPI	UniProtKB:Q86W74-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CXADR	IPI	UniProtKB:Q92520	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Cxadr	IPI	UniProtKB:P60710	Mouse	MGI:MGI:3715396|PMID:17531226
Molecular Function	GO:0005515	protein binding	Cxadr	IPI	UniProtKB:P19793	Mouse	MGI:MGI:5918779|PMID:21220114
Molecular Function	GO:0005515	protein binding	Cxadr	IPI	PR:O70263	Mouse	PMID:16410001
Molecular Function	GO:0005515	protein binding	Cxadr	IPI	PR:Q91XL2	Mouse	PMID:15979067
Molecular Function	GO:0005515	protein binding	Cxadr	IPI	PR:Q9D8B7	Mouse	PMID:16410001
Molecular Function	GO:0005515	protein binding	Cxadr	IPI	PR:Q91XL2	Mouse	PMID:16410001
Molecular Function	GO:0001618	virus receptor activity	cxadr	IDA		Zfish	PMID:12239327
Cellular Component	GO:0001669	acrosomal vesicle	Cxadr	IDA		Mouse	PMID:16410001
Cellular Component	GO:0005912	adherens junction	CXADR	IDA		Human	PMID:12297051
Cellular Component	GO:0005912	adherens junction	CXADR	IDA		Human	PMID:25468996
Cellular Component	GO:0016327	apicolateral plasma membrane	CXADR	IDA		Human	PMID:15364909
Cellular Component	GO:0016323	basolateral plasma membrane	CXADR	IDA		Human	PMID:20361046
Cellular Component	GO:0016323	basolateral plasma membrane	Cxadr	IDA		Mouse	MGI:MGI:5294314|PMID:11316797
Cellular Component	GO:0005923	bicellular tight junction	CXADR	IDA		Human	PMID:15800062
Cellular Component	GO:0005923	bicellular tight junction	CXADR	IDA		Human	PMID:22003382
Cellular Component	GO:0005923	bicellular tight junction	Cxadr	IDA		Mouse	MGI:MGI:4948795|PMID:21269662
Cellular Component	GO:0005923	bicellular tight junction	Cxadr	IDA		Mouse	MGI:MGI:5294294|PMID:17690169
Cellular Component	GO:0005923	bicellular tight junction	Cxadr	IDA		Rat	PMID:12808125|RGD:1299248
Cellular Component	GO:0005923	bicellular tight junction	Cxadr	IDA		Rat	PMID:17675666|RGD:8553448
Cellular Component	GO:0005923	bicellular tight junction	cxadr	IDA		Zfish	PMID:18062954
Cellular Component	GO:0044297	cell body	Cxadr	IDA		Mouse	MGI:MGI:5294315|PMID:10814828
Cellular Component	GO:0030054	cell junction	CXADR	IDA		Human	GO_REF:0000052
Cellular Component	GO:0009986	cell surface	cxadr	IDA		Zfish	PMID:12239327
Cellular Component	GO:0005911	cell-cell junction	CXADR	IDA		Human	PMID:17675666
Cellular Component	GO:0005911	cell-cell junction	CXADR	IDA		Human	PMID:20235596
Cellular Component	GO:0005911	cell-cell junction	Cxadr	IDA		Mouse	PMID:16678988
Cellular Component	GO:0005737	cytoplasm	CXADR	IDA		Human	PMID:22003382
Cellular Component	GO:0030175	filopodium	Cxadr	IDA		Mouse	MGI:MGI:5294315|PMID:10814828
Cellular Component	GO:0030426	growth cone	Cxadr	IDA		Mouse	MGI:MGI:5294315|PMID:10814828
Cellular Component	GO:0014704	intercalated disc	Cxadr	IDA		Mouse	MGI:MGI:3814765|PMID:18636119
Cellular Component	GO:0045121	membrane raft	CXADR	IDA		Human	PMID:17675666
Cellular Component	GO:0043005	neuron projection	Cxadr	IDA		Mouse	MGI:MGI:5294315|PMID:10814828
Cellular Component	GO:0043005	neuron projection	Cxadr	IDA		Rat	PMID:19461877|RGD:8554646
Cellular Component	GO:0005654	nucleoplasm	CXADR	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	CXADR	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	CXADR	HDA		Human	PMID:16780588
Cellular Component	GO:0005886	plasma membrane	CXADR	IDA		Human	PMID:9096397
Cellular Component	GO:0032991	protein-containing complex	CXADR	IDA		Human	PMID:17675666
Biological Process	GO:0031532	actin cytoskeleton reorganization	CXADR	IDA		Human	PMID:17675666
Biological Process	GO:0086067	AV node cell to bundle of His cell communication	Cxadr	IMP		Mouse	MGI:MGI:3814765|PMID:18636119
Biological Process	GO:0086072	AV node cell-bundle of His cell adhesion involved in cell communication	Cxadr	IMP		Mouse	MGI:MGI:3814765|PMID:18636119
Biological Process	GO:0055013	cardiac muscle cell development	Cxadr	IMP	MGI:MGI:3587803	Mouse	PMID:16079292
Biological Process	GO:0060038	cardiac muscle cell proliferation	Cxadr	IMP	MGI:MGI:3711226	Mouse	PMID:16543498
Biological Process	GO:0098609	cell-cell adhesion	Cxadr	IMP		Mouse	MGI:MGI:5294315|PMID:10814828
Biological Process	GO:0045216	cell-cell junction organization	Cxadr	IMP	MGI:MGI:3711226	Mouse	PMID:16543498
Biological Process	GO:0010669	epithelial structure maintenance	CXADR	IMP		Human	PMID:15304526
Biological Process	GO:0046629	gamma-delta T cell activation	Cxadr	IDA		Mouse	MGI:MGI:4822257|PMID:20813954
Biological Process	GO:0008354	germ cell migration	Cxadr	IEP		Mouse	MGI:MGI:5294294|PMID:17690169
Biological Process	GO:0007507	heart development	Cxadr	IMP	MGI:MGI:3583765	Mouse	PMID:15864812
Biological Process	GO:0007507	heart development	Cxadr	IMP	MGI:MGI:3711226	Mouse	PMID:16543498
Biological Process	GO:0007507	heart development	Cxadr	IMP	MGI:MGI:3587803	Mouse	PMID:16079292
Biological Process	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	CXADR	IDA		Human	PMID:12869515
Biological Process	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	CXADR	IDA		Human	PMID:15800062
Biological Process	GO:0001822	kidney development	cxadr	IMP	ZFIN:ZDB-MRPHLNO-080509-4	Zfish	PMID:18062954
Biological Process	GO:0001822	kidney development	cxadr	IMP	ZFIN:ZDB-MRPHLNO-080509-5	Zfish	PMID:18062954
Biological Process	GO:0007005	mitochondrion organization	Cxadr	IMP	MGI:MGI:3587803	Mouse	PMID:16079292
Biological Process	GO:0060044	negative regulation of cardiac muscle cell proliferation	Cxadr	IMP	MGI:MGI:3711226	Mouse	PMID:16543498
Biological Process	GO:0030593	neutrophil chemotaxis	CXADR	IMP		Human	PMID:15800062
Biological Process	GO:0098904	regulation of AV node cell action potential	Cxadr	IMP		Mouse	MGI:MGI:3814765|PMID:18636119
Biological Process	GO:0070633	transepithelial transport	CXADR	IMP		Human	PMID:15800062

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern