Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CXCL13
  • Mouse genes Cxcl13
  • Rat genes Cxcl13
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cxcl13

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031735	CCR10 chemokine receptor binding	CXCL13	IDA		Human	PMID:10706668
Molecular Function	GO:0008009	chemokine activity	CXCL13	IDA		Human	PMID:11554781
Molecular Function	GO:0008009	chemokine activity	Cxcl13	IDA		Mouse	MGI:MGI:3702377|PMID:15972452
Molecular Function	GO:0048248	CXCR3 chemokine receptor binding	CXCL13	IPI	UniProtKB:P49682	Human	PMID:11554781
Molecular Function	GO:0031724	CXCR5 chemokine receptor binding	CXCL13	IDA		Human	PMID:9463416
Molecular Function	GO:0031724	CXCR5 chemokine receptor binding	Cxcl13	IDA		Mouse	MGI:MGI:5009211|PMID:9463416
Molecular Function	GO:0017134	fibroblast growth factor binding	CXCL13	IDA		Human	PMID:11708770
Molecular Function	GO:0017134	fibroblast growth factor binding	CXCL13	IPI	UniProtKB:P09038	Human	PMID:11708770
Molecular Function	GO:0008201	heparin binding	CXCL13	IDA		Human	PMID:11708770
Molecular Function	GO:0048018	receptor ligand activity	CXCL13	IDA		Human	PMID:11554781
Cellular Component	GO:0005576	extracellular region	CXCL13	IDA		Human	PMID:17562761
Cellular Component	GO:0005576	extracellular region	CXCL13	IDA		Human	PMID:17652619
Cellular Component	GO:0005615	extracellular space	Cxcl13	IDA		Mouse	PMID:23460747
Biological Process	GO:0090630	activation of GTPase activity	Cxcl13	IDA		Mouse	MGI:MGI:3702377|PMID:15972452
Biological Process	GO:0035754	B cell chemotaxis	CXCL13	IDA		Human	PMID:9463416
Biological Process	GO:0035754	B cell chemotaxis	Cxcl13	IMP		Mouse	MGI:MGI:3702377|PMID:15972452
Biological Process	GO:0035769	B cell chemotaxis across high endothelial venule	Cxcl13	IDA		Mouse	MGI:MGI:3702377|PMID:15972452
Biological Process	GO:0007166	cell surface receptor signaling pathway	CXCL13	IDA		Human	PMID:11554781
Biological Process	GO:0007267	cell-cell signaling	CXCL13	IDA		Human	PMID:11554781
Biological Process	GO:0042742	defense response to bacterium	CXCL13	IDA		Human	PMID:17562761
Biological Process	GO:0035768	endothelial cell chemotaxis to fibroblast growth factor	CXCL13	IDA		Human	PMID:11708770
Biological Process	GO:0048535	lymph node development	Cxcl13	IDA		Mouse	MGI:MGI:4436841|PMID:19783990
Biological Process	GO:0048535	lymph node development	Cxcl13	IMP	MGI:MGI:2384500	Mouse	PMID:12732660
Biological Process	GO:0002518	lymphocyte chemotaxis across high endothelial venule	Cxcl13	IMP		Mouse	MGI:MGI:3702377|PMID:15972452
Biological Process	GO:2000545	negative regulation of endothelial cell chemotaxis to fibroblast growth factor	CXCL13	IDA		Human	PMID:11708770
Biological Process	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin	Cxcl13	IDA		Mouse	MGI:MGI:3702377|PMID:15972452
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	CXCL13	IDA		Human	PMID:11554781
Biological Process	GO:0033625	positive regulation of integrin activation	Cxcl13	IDA		Mouse	MGI:MGI:3702377|PMID:15972452
Biological Process	GO:0010820	positive regulation of T cell chemotaxis	CXCL13	IDA		Human	PMID:11554781

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern