Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CXCL16
  • Mouse genes Cxcl16
  • Rat genes Cxcl16
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cxcl16

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008009	chemokine activity	CXCL16	IDA		Human	PMID:18373975
Molecular Function	GO:0008009	chemokine activity	Cxcl16	IDA		Mouse	PMID:11017100
Molecular Function	GO:0042379	chemokine receptor binding	Cxcl16	IPI	UniProtKB:Q9EQ16	Mouse	MGI:MGI:1891794|PMID:11017100
Molecular Function	GO:0005041	low-density lipoprotein particle receptor activity	Cxcl16	IDA		Mouse	PMID:11060282
Molecular Function	GO:0005044	scavenger receptor activity	Cxcl16	IDA		Mouse	PMID:11060282
Cellular Component	GO:0005615	extracellular space	CXCL16	IDA		Human	PMID:18373975
Cellular Component	GO:0005615	extracellular space	Cxcl16	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Cellular Component	GO:0005615	extracellular space	Cxcl16	IDA		Mouse	MGI:MGI:1891794|PMID:11017100
Cellular Component	GO:0016020	membrane	Cxcl16	IDA		Mouse	MGI:MGI:1891794|PMID:11017100
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Cxcl16	IDA		Mouse	MGI:MGI:1891794|PMID:11017100
Biological Process	GO:0006897	endocytosis	Cxcl16	IDA		Mouse	MGI:MGI:1929021|PMID:11060282
Biological Process	GO:0030307	positive regulation of cell growth	CXCL16	IMP		Human	PMID:18373975
Biological Process	GO:0030335	positive regulation of cell migration	CXCL16	IMP		Human	PMID:18373975
Biological Process	GO:0034097	response to cytokine	CXCL16	IDA		Human	PMID:18373975
Biological Process	GO:0034612	response to tumor necrosis factor	CXCL16	IDA		Human	PMID:18373975
Biological Process	GO:0034341	response to type II interferon	CXCL16	IDA		Human	PMID:18373975
Biological Process	GO:0010818	T cell chemotaxis	Cxcl16	IDA		Mouse	MGI:MGI:1891794|PMID:11017100

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern