Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CXXC1
  • Mouse genes Cxxc1
  • Rat genes Cxxc1
  • Zfish genes cxxc1a,cxxc1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cxxc1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	Cxxc1	IDA		Rat	PMID:21814290|RGD:9587757
Molecular Function	GO:0035064	methylated histone binding	Cxxc1	IDA		Mouse	MGI:MGI:6258144|PMID:30365547
Molecular Function	GO:0005515	protein binding	CXXC1	IPI	UniProtKB:O15047	Human	PMID:17998332
Molecular Function	GO:0005515	protein binding	CXXC1	IPI	UniProtKB:P60484	Human	PMID:21653829
Molecular Function	GO:0005515	protein binding	CXXC1	IPI	UniProtKB:P04637	Human	PMID:23870121
Molecular Function	GO:0005515	protein binding	CXXC1	IPI	UniProtKB:Q15291	Human	PMID:23870121
Molecular Function	GO:0005515	protein binding	CXXC1	IPI	UniProtKB:P50222	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CXXC1	IPI	UniProtKB:Q86VP1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CXXC1	IPI	UniProtKB:Q15291	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	Cxxc1	IPI	UniProtKB:Q96EQ9	Mouse	MGI:MGI:6355525|PMID:27932493
Molecular Function	GO:0005515	protein binding	Cxxc1	IPI	UniProtKB:Q96EQ9	Mouse	MGI:MGI:6258144|PMID:30365547
Molecular Function	GO:0045322	unmethylated CpG binding	CXXC1	IDA		Human	PMID:10688657
Cellular Component	GO:0005829	cytosol	CXXC1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0035097	histone methyltransferase complex	CXXC1	IDA		Human	PMID:17355966
Cellular Component	GO:0016363	nuclear matrix	Cxxc1	IDA		Mouse	PMID:12200428
Cellular Component	GO:0016607	nuclear speck	CXXC1	IDA		Human	GO_REF:0000054
Cellular Component	GO:0005654	nucleoplasm	CXXC1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	CXXC1	IDA		Human	PMID:10688657
Cellular Component	GO:0005634	nucleus	Cxxc1	IDA		Mouse	MGI:MGI:6258144|PMID:30365547
Cellular Component	GO:0048188	Set1C/COMPASS complex	CXXC1	IPI		Human	PMID:23508102
Cellular Component	GO:0048188	Set1C/COMPASS complex	CXXC1	IDA		Human	PMID:17998332
Cellular Component	GO:0048188	Set1C/COMPASS complex	CXXC1	IDA		Human	PMID:18838538
Biological Process	GO:0001568	blood vessel development	cxxc1b	IMP	ZFIN:ZDB-MRPHLNO-070207-1	Zfish	PMID:17023431
Biological Process	GO:0032776	DNA methylation on cytosine	cxxc1b	IMP	ZFIN:ZDB-MRPHLNO-070207-1	Zfish	PMID:17023431
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	cxxc1a	IMP		Zfish	PMID:24240475
Biological Process	GO:0030097	hemopoiesis	cxxc1b	IMP	ZFIN:ZDB-MRPHLNO-070207-1	Zfish	PMID:17023431
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	CXXC1	IDA		Human	PMID:10688657
Biological Process	GO:0006355	regulation of DNA-templated transcription	CXXC1	IDA		Human	PMID:10688657

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern