Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CYB561A3
  • Mouse genes Cyb561a3
  • Rat genes Cyb561a3
  • Zfish genes cyb561a3a,cyb561a3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cyb561a3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	CYB561A3	IPI	UniProtKB:Q99942	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CYB561A3	IPI	UniProtKB:O00501	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB561A3	IPI	UniProtKB:O15552	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB561A3	IPI	UniProtKB:O60883	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB561A3	IPI	UniProtKB:O95471	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB561A3	IPI	UniProtKB:P11912	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB561A3	IPI	UniProtKB:P15151	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB561A3	IPI	UniProtKB:P25942	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB561A3	IPI	UniProtKB:P26715	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB561A3	IPI	UniProtKB:Q08426	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB561A3	IPI	UniProtKB:Q13520	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB561A3	IPI	UniProtKB:Q3SXP7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB561A3	IPI	UniProtKB:Q68CJ9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB561A3	IPI	UniProtKB:Q86VI4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB561A3	IPI	UniProtKB:Q8TDT2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB561A3	IPI	UniProtKB:Q8TED1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB561A3	IPI	UniProtKB:Q96CE8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB561A3	IPI	UniProtKB:Q96GF1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB561A3	IPI	UniProtKB:Q96P66	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB561A3	IPI	UniProtKB:Q99942	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB561A3	IPI	UniProtKB:Q9BSE4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB561A3	IPI	UniProtKB:Q9NUQ2	Human	PMID:32296183
Molecular Function	GO:0140571	transmembrane ascorbate ferrireductase activity	Cyb561a3	IDA		Mouse	MGI:MGI:6508497|PMID:16911521
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	CYB561A3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0031902	late endosome membrane	Cyb561a3	IDA		Mouse	MGI:MGI:3695337|PMID:16996694
Cellular Component	GO:0005765	lysosomal membrane	CYB561A3	HDA		Human	PMID:17897319
Cellular Component	GO:0005765	lysosomal membrane	Cyb561a3	IDA		Mouse	MGI:MGI:3695337|PMID:16996694
Cellular Component	GO:0005764	lysosome	Cyb561a3	IDA		Mouse	PMID:16996694
Cellular Component	GO:0005730	nucleolus	CYB561A3	IDA		Human	GO_REF:0000052
Biological Process	GO:0006879	intracellular iron ion homeostasis	Cyb561a3	IDA		Mouse	MGI:MGI:6508497|PMID:16911521

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern