Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CYB5A
  • Mouse genes Cyb5a
  • Rat genes Cyb5a
  • Zfish genes cyb5a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cyb5a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	CYB5A	IPI	UniProtKB:P05177	Human	PMID:15680923
Molecular Function	GO:0019899	enzyme binding	CYB5A	IPI	UniProtKB:P05181	Human	PMID:15680923
Molecular Function	GO:0019899	enzyme binding	CYB5A	IPI	UniProtKB:P08684	Human	PMID:15680923
Molecular Function	GO:0019899	enzyme binding	CYB5A	IPI	UniProtKB:P11509	Human	PMID:15680923
Molecular Function	GO:0020037	heme binding	cyb5a	IDA		Zfish	PMID:31257865
Molecular Function	GO:0016491	oxidoreductase activity	cyb5a	IDA		Zfish	PMID:31257865
Molecular Function	GO:0005515	protein binding	CYB5A	IPI	UniProtKB:D3DTS7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CYB5A	IPI	UniProtKB:O60333-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CYB5A	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CYB5A	IPI	UniProtKB:P28799	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CYB5A	IPI	UniProtKB:Q9Y3C5	Human	PMID:32814053
Cellular Component	GO:0005829	cytosol	CYB5A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005783	endoplasmic reticulum	Cyb5a	IDA		Mouse	PMID:31006538
Cellular Component	GO:0005783	endoplasmic reticulum	Cyb5a	IDA		Rat	PMID:14561759|RGD:1580664
Cellular Component	GO:0005789	endoplasmic reticulum membrane	Cyb5a	IDA		Rat	PMID:12761189|RGD:1599660
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	CYB5A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	Cyb5a	IDA		Rat	PMID:18641804|RGD:2316213
Cellular Component	GO:0016020	membrane	CYB5A	HDA		Human	PMID:19946888
Cellular Component	GO:0016020	membrane	CYB5A	IDA		Human	PMID:22375059
Cellular Component	GO:0005739	mitochondrion	Cyb5a	HDA		Mouse	PMID:14651853
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	cyb5a	IDA		Zfish	PMID:18618001
Biological Process	GO:0046686	response to cadmium ion	Cyb5a	IEP		Rat	PMID:14595535|RGD:1599661

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern