Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CYB5B
  • Mouse genes Cyb5b
  • Rat genes Cyb5b
  • Zfish genes cyb5b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cyb5b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008047	enzyme activator activity	Cyb5b	IDA		Rat	PMID:12668680|RGD:1582390
Molecular Function	GO:0020037	heme binding	CYB5B	IDA		Human	PMID:20861021
Molecular Function	GO:0020037	heme binding	cyb5b	IDA		Zfish	PMID:31257865
Molecular Function	GO:0050421	nitrite reductase (NO-forming) activity	CYB5B	IDA		Human	PMID:24500710
Molecular Function	GO:0016491	oxidoreductase activity	cyb5b	IDA		Zfish	PMID:31257865
Molecular Function	GO:0005515	protein binding	CYB5B	IPI	UniProtKB:Q99IB8:PRO_0000045601	Human	PMID:25616068
Molecular Function	GO:0005515	protein binding	CYB5B	IPI	UniProtKB:A2A2Y4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5B	IPI	UniProtKB:O60238	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5B	IPI	UniProtKB:O95279	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5B	IPI	UniProtKB:O95377	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5B	IPI	UniProtKB:O95471	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5B	IPI	UniProtKB:P11912	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5B	IPI	UniProtKB:P15941-11	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5B	IPI	UniProtKB:P20138	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5B	IPI	UniProtKB:P21579	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5B	IPI	UniProtKB:P27105	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5B	IPI	UniProtKB:P43628	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5B	IPI	UniProtKB:Q13113	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5B	IPI	UniProtKB:Q13323	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5B	IPI	UniProtKB:Q13520	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5B	IPI	UniProtKB:Q15125	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5B	IPI	UniProtKB:Q16623	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5B	IPI	UniProtKB:Q3KNW5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5B	IPI	UniProtKB:Q53FP2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5B	IPI	UniProtKB:Q5JX71	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5B	IPI	UniProtKB:Q5SR56	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5B	IPI	UniProtKB:Q5T0T0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5B	IPI	UniProtKB:Q5TF39	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5B	IPI	UniProtKB:Q5VUM1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5B	IPI	UniProtKB:Q5VZY2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5B	IPI	UniProtKB:Q6N075	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5B	IPI	UniProtKB:Q6UXG8-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5B	IPI	UniProtKB:Q7Z7G2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5B	IPI	UniProtKB:Q86VR2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5B	IPI	UniProtKB:Q8IV31	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5B	IPI	UniProtKB:Q8IVF2-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5B	IPI	UniProtKB:Q8N183	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5B	IPI	UniProtKB:Q8N661	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5B	IPI	UniProtKB:Q8TBE3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5B	IPI	UniProtKB:Q8TDT2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5B	IPI	UniProtKB:Q96HV5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5B	IPI	UniProtKB:Q96KR6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5B	IPI	UniProtKB:Q96KR7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5B	IPI	UniProtKB:Q96Q45-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5B	IPI	UniProtKB:Q99675	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5B	IPI	UniProtKB:Q9GZY8-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5B	IPI	UniProtKB:Q9H6H4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5B	IPI	UniProtKB:Q9NUM3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5B	IPI	UniProtKB:Q9P2J2-2	Human	PMID:32296183
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	Cyb5b	IDA		Rat	PMID:12668680|RGD:1582390
Cellular Component	GO:0016020	membrane	CYB5B	HDA		Human	PMID:19946888
Cellular Component	GO:0005743	mitochondrial inner membrane	Cyb5b	HDA		Mouse	PMID:12865426
Cellular Component	GO:0005741	mitochondrial outer membrane	Cyb5b	IDA		Rat	PMID:12668680|RGD:1582390
Cellular Component	GO:0005741	mitochondrial outer membrane	Cyb5b	IDA		Rat	PMID:6840088|RGD:14397582
Cellular Component	GO:0005739	mitochondrion	Cyb5b	HDA		Mouse	PMID:18614015
Cellular Component	GO:1903958	nitric-oxide synthase complex	CYB5B	IDA		Human	PMID:24500710
Biological Process	GO:0006809	nitric oxide biosynthetic process	CYB5B	IDA		Human	PMID:24500710

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern