Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CYB5R3
  • Mouse genes Cyb5r3
  • Rat genes Cyb5r3
  • Zfish genes cyb5r3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cyb5r3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043531	ADP binding	Cyb5r3	IDA		Rat	PMID:14609324|RGD:1599772
Molecular Function	GO:0016208	AMP binding	Cyb5r3	IDA		Rat	PMID:14609324|RGD:1599772
Molecular Function	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H	CYB5R3	IMP		Human	PMID:10807796
Molecular Function	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H	CYB5R3	IDA		Human	PMID:1400360
Molecular Function	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H	CYB5R3	IMP		Human	PMID:15953014
Molecular Function	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H	CYB5R3	IMP		Human	PMID:1898726
Molecular Function	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H	CYB5R3	IMP		Human	PMID:2019583
Molecular Function	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H	CYB5R3	IMP		Human	PMID:8119939
Molecular Function	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H	CYB5R3	IDA		Human	PMID:9639531
Molecular Function	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H	Cyb5r3	IDA		Rat	PMID:11695905|RGD:153298935
Molecular Function	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H	Cyb5r3	IDA		Rat	PMID:8812833|RGD:153298951
Molecular Function	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H	Cyb5r3	IDA		Rat	PMID:8978818|RGD:153298962
Molecular Function	GO:0071949	FAD binding	CYB5R3	IDA		Human	PMID:1400360
Molecular Function	GO:0071949	FAD binding	CYB5R3	IDA		Human	PMID:15502298
Molecular Function	GO:0071949	FAD binding	CYB5R3	IDA		Human	PMID:15953014
Molecular Function	GO:0071949	FAD binding	Cyb5r3	IDA		Rat	PMID:11695905|RGD:153298935
Molecular Function	GO:0071949	FAD binding	Cyb5r3	IDA		Rat	PMID:8812833|RGD:153298951
Molecular Function	GO:0050660	flavin adenine dinucleotide binding	Cyb5r3	IDA		Rat	PMID:14609324|RGD:1599772
Molecular Function	GO:0051287	NAD binding	Cyb5r3	IDA		Rat	PMID:14609324|RGD:1599772
Molecular Function	GO:0003954	NADH dehydrogenase activity	cyb5r3	IDA		Zfish	PMID:31257865
Molecular Function	GO:0050421	nitrite reductase (NO-forming) activity	CYB5R3	IDA		Human	PMID:24500710
Molecular Function	GO:0016491	oxidoreductase activity	cyb5r3	IDA		Zfish	PMID:31257865
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:P69905	Human	PMID:23123858
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:O14735	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:O14798	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:O75379	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:O75427	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:O95183	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:O95406	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:P01350	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:P01375	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:P07306	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:P23763-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:P27105	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:P42857	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:P54315	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:Q08AM2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:Q12893	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:Q12982	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:Q13520	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:Q13571	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:Q14416	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:Q14508	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:Q14802-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:Q14973	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:Q3KNW5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:Q4VAQ0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:Q53FV1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:Q5SNT2-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:Q6RW13-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:Q6ZSS7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:Q7Z5P4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:Q8IXM6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:Q8N6G5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:Q8TB61	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:Q8TDT2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:Q8WWT9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:Q92520	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:Q92982	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:Q969Y0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:Q96G79	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:Q96GC9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:Q96IV6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:Q96KR6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:Q96MV8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:Q9BSE2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:Q9BVK2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:Q9BWH2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:Q9GZR5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:Q9H2L4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:Q9H6H4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:Q9HA82	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:Q9NUH8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:Q9NVC3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:Q9NVV5-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:Q9NW97	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:Q9P0S9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYB5R3	IPI	UniProtKB:Q9Y5Z9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Cyb5r3	IPI	UniProtKB:Q8BT35	Mouse	MGI:MGI:6283949|PMID:30796188
Molecular Function	GO:0005515	protein binding	Cyb5r3	IPI	PR:E9Q9D5	Mouse	PMID:23055941
Cellular Component	GO:0005783	endoplasmic reticulum	CYB5R3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005789	endoplasmic reticulum membrane	CYB5R3	IDA		Human	PMID:9639531
Cellular Component	GO:0005789	endoplasmic reticulum membrane	Cyb5r3	IDA		Rat	PMID:14561759|RGD:1580664
Cellular Component	GO:0005789	endoplasmic reticulum membrane	Cyb5r3	IDA		Rat	PMID:8978818|RGD:153298962
Cellular Component	GO:0005811	lipid droplet	CYB5R3	IDA		Human	PMID:14741744
Cellular Component	GO:0016020	membrane	CYB5R3	HDA		Human	PMID:19946888
Cellular Component	GO:0005743	mitochondrial inner membrane	Cyb5r3	HDA		Mouse	PMID:12865426
Cellular Component	GO:0031966	mitochondrial membrane	CYB5R3	IDA		Human	PMID:9639531
Cellular Component	GO:0005741	mitochondrial outer membrane	Cyb5r3	IDA		Rat	PMID:8978818|RGD:153298962
Cellular Component	GO:0005739	mitochondrion	CYB5R3	HDA		Human	PMID:20833797
Cellular Component	GO:1903958	nitric-oxide synthase complex	CYB5R3	IDA		Human	PMID:24500710
Biological Process	GO:0006809	nitric oxide biosynthetic process	CYB5R3	IDA		Human	PMID:24500710

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern