Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Cyba

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes CYBA
- Mouse genes Cyba
- Rat genes Cyba
- Zfish genes cyba
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cyba

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0009055	electron transfer activity	CYBA	IDA		Human	PMID:12042318
Molecular Function	GO:0005515	protein binding	CYBA	IPI	UniProtKB:P14598	Human	PMID:11733522
Molecular Function	GO:0005515	protein binding	CYBA	IPI	UniProtKB:P19878	Human	PMID:11733522
Molecular Function	GO:0005515	protein binding	CYBA	IPI	UniProtKB:P14598	Human	PMID:16326715
Molecular Function	GO:0005515	protein binding	CYBA	IPI	UniProtKB:Q8NFA2	Human	PMID:16460309
Molecular Function	GO:0005515	protein binding	CYBA	IPI	UniProtKB:Q8NFA2	Human	PMID:17126813
Molecular Function	GO:0005515	protein binding	CYBA	IPI	UniProtKB:P14598	Human	PMID:17803994
Molecular Function	GO:0005515	protein binding	CYBA	IPI	UniProtKB:Q8NFA2-3	Human	PMID:23957209
Molecular Function	GO:0005515	protein binding	CYBA	IPI	UniProtKB:P04839	Human	PMID:3305576
Molecular Function	GO:0005515	protein binding	Cyba	IPI	UniProtKB:Q91Z40	Mouse	MGI:MGI:5007562\|PMID:21551061
Molecular Function	GO:0005515	protein binding	Cyba	IPI	UniProtKB:O89032	Mouse	MGI:MGI:5285168\|PMID:19755709
Molecular Function	GO:0005515	protein binding	Cyba	IPI	UniProtKB:Q61093	Mouse	MGI:MGI:5568138\|PMID:24739962
Molecular Function	GO:0005515	protein binding	Cyba	IPI	RGD:620598	Rat	PMID:15322091\|RGD:1580287
Molecular Function	GO:0005515	protein binding	Cyba	IPI	RGD:1307022	Rat	PMID:19574552\|RGD:11040550
Molecular Function	GO:0046982	protein heterodimerization activity	CYBA	IPI	UniProtKB:P04839	Human	PMID:12042318
Molecular Function	GO:0017124	SH3 domain binding	CYBA	IPI	UniProtKB:P14598	Human	PMID:7938008
Molecular Function	GO:0016175	superoxide-generating NAD(P)H oxidase activity	CYBA	IMP		Human	PMID:1763037
Molecular Function	GO:0016175	superoxide-generating NAD(P)H oxidase activity	Cyba	IMP		Rat	PMID:8798532\|RGD:2317869
Cellular Component	GO:0016324	apical plasma membrane	Cyba	IDA		Rat	PMID:19536508\|RGD:2317856
Cellular Component	GO:0005737	cytoplasm	Cyba	IDA		Mouse	PMID:15850784
Cellular Component	GO:0030425	dendrite	Cyba	IDA		Rat	PMID:17027166\|RGD:1599676
Cellular Component	GO:0005768	endosome	Cyba	IDA		Mouse	PMID:24185898
Cellular Component	GO:0005925	focal adhesion	Cyba	IDA		Rat	PMID:19574552\|RGD:11040550
Cellular Component	GO:0005794	Golgi apparatus	Cyba	IDA		Rat	PMID:17027166\|RGD:1599676
Cellular Component	GO:0016020	membrane	CYBA	HDA		Human	PMID:19946888
Cellular Component	GO:0005739	mitochondrion	Cyba	HDA		Mouse	PMID:14651853
Cellular Component	GO:0043020	NADPH oxidase complex	CYBA	IMP		Human	PMID:1763037
Cellular Component	GO:0043020	NADPH oxidase complex	CYBA	IDA		Human	PMID:3305576
Cellular Component	GO:0043020	NADPH oxidase complex	Cyba	IDA		Mouse	MGI:MGI:5568138\|PMID:24739962
Cellular Component	GO:0043020	NADPH oxidase complex	Cyba	IDA		Rat	PMID:12241540\|RGD:2291907
Cellular Component	GO:0043020	NADPH oxidase complex	Cyba	IDA		Rat	PMID:15322091\|RGD:1580287
Cellular Component	GO:0043020	NADPH oxidase complex	Cyba	IMP		Rat	PMID:8798532\|RGD:2317869
Cellular Component	GO:0043025	neuronal cell body	Cyba	IDA		Rat	PMID:17027166\|RGD:1599676
Cellular Component	GO:0005634	nucleus	Cyba	IDA		Rat	PMID:19574552\|RGD:11040550
Cellular Component	GO:0097038	perinuclear endoplasmic reticulum	Cyba	IDA		Rat	PMID:10938010\|RGD:632513
Cellular Component	GO:0001725	stress fiber	Cyba	IDA		Rat	PMID:19574552\|RGD:11040550
Biological Process	GO:0071230	cellular response to amino acid stimulus	Cyba	IEP		Rat	PMID:12241540\|RGD:2291907
Biological Process	GO:1904385	cellular response to angiotensin	Cyba	IEP		Rat	PMID:16257643\|RGD:11040554
Biological Process	GO:0071480	cellular response to gamma radiation	Cyba	IEP		Rat	PMID:18640264\|RGD:2317861
Biological Process	GO:0071333	cellular response to glucose stimulus	Cyba	IEP		Rat	PMID:15479219\|RGD:11040556
Biological Process	GO:0071333	cellular response to glucose stimulus	Cyba	IEP		Rat	PMID:19609456\|RGD:2317855
Biological Process	GO:1904845	cellular response to L-glutamine	Cyba	IEP		Rat	PMID:12241540\|RGD:2291907
Biological Process	GO:0071260	cellular response to mechanical stimulus	Cyba	IEP		Rat	PMID:16685209\|RGD:2317865
Biological Process	GO:0071407	cellular response to organic cyclic compound	Cyba	IEP		Rat	PMID:12241540\|RGD:2291907
Biological Process	GO:0071310	cellular response to organic substance	Cyba	IDA		Rat	PMID:19445920\|RGD:2317857
Biological Process	GO:0071356	cellular response to tumor necrosis factor	Cyba	IEP		Rat	PMID:9445395\|RGD:2317868
Biological Process	GO:0017004	cytochrome complex assembly	CYBA	IDA		Human	PMID:7938008
Biological Process	GO:0051649	establishment of localization in cell	Cyba	IMP	MGI:MGI:3526726	Mouse	PMID:24185898
Biological Process	GO:0050665	hydrogen peroxide biosynthetic process	Cyba	IMP		Rat	PMID:8798532\|RGD:2317869
Biological Process	GO:0006954	inflammatory response	CYBA	IMP		Human	PMID:2243141
Biological Process	GO:0045087	innate immune response	CYBA	IMP		Human	PMID:2243141
Biological Process	GO:0045087	innate immune response	Cyba	IMP		Mouse	MGI:MGI:5901952\|PMID:28351984
Biological Process	GO:0048246	macrophage chemotaxis	cyba	IMP	ZFIN:ZDB-MRPHLNO-091117-3	Zfish	PMID:25488917
Biological Process	GO:0070254	mucus secretion	Cyba	IMP	MGI:MGI:3526726	Mouse	PMID:24185898
Biological Process	GO:0003106	negative regulation of glomerular filtration by angiotensin	Cyba	IMP		Rat	PMID:17220186\|RGD:2317863
Biological Process	GO:1990266	neutrophil migration	cyba	IGI	ZFIN:ZDB-GENE-091120-9	Zfish	PMID:24835391
Biological Process	GO:0045777	positive regulation of blood pressure	Cyba	IMP		Rat	PMID:16391171\|RGD:1600795
Biological Process	GO:0030307	positive regulation of cell growth	Cyba	IMP		Rat	PMID:8798532\|RGD:2317869
Biological Process	GO:1900426	positive regulation of defense response to bacterium	CYBA	IDA		Human	PMID:22423966
Biological Process	GO:0001938	positive regulation of endothelial cell proliferation	Cyba	IMP		Rat	PMID:14871555\|RGD:1580270
Biological Process	GO:0032755	positive regulation of interleukin-6 production	CYBA	IDA		Human	PMID:22423966
Biological Process	GO:0070257	positive regulation of mucus secretion	Cyba	IMP	MGI:MGI:3526726	Mouse	PMID:24185898
Biological Process	GO:0033864	positive regulation of NAD(P)H oxidase activity	Cyba	IMP		Rat	PMID:12631082\|RGD:11040676
Biological Process	GO:0050766	positive regulation of phagocytosis	CYBA	IDA		Human	PMID:22423966
Biological Process	GO:1903428	positive regulation of reactive oxygen species biosynthetic process	CYBA	IDA		Human	PMID:22423966
Biological Process	GO:0048661	positive regulation of smooth muscle cell proliferation	Cyba	IMP		Rat	PMID:15036821\|RGD:8693734
Biological Process	GO:0032930	positive regulation of superoxide anion generation	Cyba	IMP		Rat	PMID:15036821\|RGD:8693734
Biological Process	GO:0034137	positive regulation of toll-like receptor 2 signaling pathway	CYBA	IDA		Human	PMID:22423966
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	CYBA	IDA		Human	PMID:22423966
Biological Process	GO:0072593	reactive oxygen species metabolic process	Cyba	IMP	MGI:MGI:3526726	Mouse	PMID:24185898
Biological Process	GO:0051279	regulation of release of sequestered calcium ion into cytosol	Cyba	IMP	MGI:MGI:3526726	Mouse	PMID:24185898
Biological Process	GO:0045730	respiratory burst	CYBA	IMP		Human	PMID:2243141
Biological Process	GO:0014823	response to activity	Cyba	IEP		Rat	PMID:23905384\|RGD:11040693
Biological Process	GO:1904044	response to aldosterone	Cyba	IEP		Rat	PMID:21824999\|RGD:11040695
Biological Process	GO:0001666	response to hypoxia	Cyba	IEP		Rat	PMID:22372715\|RGD:11040694
Biological Process	GO:0070555	response to interleukin-1	Cyba	IEP		Rat	PMID:16183707\|RGD:2317866
Biological Process	GO:0031667	response to nutrient levels	Cyba	IEP		Rat	PMID:15649487\|RGD:2317867
Biological Process	GO:0009410	response to xenobiotic stimulus	Cyba	IEP		Rat	PMID:17530711\|RGD:4774627
Biological Process	GO:0014895	smooth muscle hypertrophy	Cyba	IMP		Rat	PMID:8798532\|RGD:2317869
Biological Process	GO:0042554	superoxide anion generation	CYBA	IMP		Human	PMID:2243141
Biological Process	GO:0042554	superoxide anion generation	Cyba	IMP		Rat	PMID:8798532\|RGD:2317869
Biological Process	GO:0006801	superoxide metabolic process	CYBA	IMP		Human	PMID:1763037
Biological Process	GO:0006801	superoxide metabolic process	CYBA	IMP		Human	PMID:2243141
Biological Process	GO:0006801	superoxide metabolic process	Cyba	IDA		Rat	PMID:15322091\|RGD:1580287
Biological Process	GO:0006801	superoxide metabolic process	Cyba	IMP		Rat	PMID:8798532\|RGD:2317869

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.