Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CYBRD1
  • Mouse genes Cybrd1
  • Rat genes Cybrd1
  • Zfish genes cybrd1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cybrd1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	CYBRD1	IDA		Human	PMID:30272000
Molecular Function	GO:0016722	oxidoreductase activity, acting on metal ions	CYBRD1	IDA		Human	PMID:14499595
Molecular Function	GO:0005515	protein binding	CYBRD1	IPI	UniProtKB:Q12846	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	CYBRD1	IPI	UniProtKB:Q12846	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CYBRD1	IPI	UniProtKB:Q12846	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	CYBRD1	IPI	UniProtKB:O14653	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYBRD1	IPI	UniProtKB:O15400	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYBRD1	IPI	UniProtKB:O95159	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYBRD1	IPI	UniProtKB:O95292	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYBRD1	IPI	UniProtKB:P09601	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYBRD1	IPI	UniProtKB:Q04941	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYBRD1	IPI	UniProtKB:Q14318	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYBRD1	IPI	UniProtKB:Q6PI78	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYBRD1	IPI	UniProtKB:Q8N6R1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYBRD1	IPI	UniProtKB:Q96F15	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYBRD1	IPI	UniProtKB:Q96IW7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYBRD1	IPI	UniProtKB:Q9BXJ8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYBRD1	IPI	UniProtKB:Q9P0L0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYBRD1	IPI	UniProtKB:Q9UBY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYBRD1	IPI	UniProtKB:Q9UI14	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYBRD1	IPI	UniProtKB:Q9Y6X1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYBRD1	IPI	UniProtKB:O75400-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CYBRD1	IPI	UniProtKB:P13473-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CYBRD1	IPI	UniProtKB:P55212	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CYBRD1	IPI	UniProtKB:Q9Y371	Human	PMID:32814053
Molecular Function	GO:0140571	transmembrane ascorbate ferrireductase activity	CYBRD1	IDA		Human	PMID:17068337
Molecular Function	GO:0140571	transmembrane ascorbate ferrireductase activity	CYBRD1	IDA		Human	PMID:30272000
Molecular Function	GO:0140571	transmembrane ascorbate ferrireductase activity	Cybrd1	IDA		Mouse	MGI:MGI:3697277|PMID:17068337
Molecular Function	GO:0140575	transmembrane monodehydroascorbate reductase activity	CYBRD1	IDA		Human	PMID:17068337
Cellular Component	GO:0016324	apical plasma membrane	CYBRD1	IDA		Human	PMID:12949720
Cellular Component	GO:0031526	brush border membrane	CYBRD1	IDA		Human	PMID:12949720
Cellular Component	GO:0031526	brush border membrane	Cybrd1	IDA		Mouse	PMID:11230685
Cellular Component	GO:0070062	extracellular exosome	CYBRD1	HDA		Human	PMID:19056867
Cellular Component	GO:0016020	membrane	CYBRD1	IDA		Human	PMID:30272000
Cellular Component	GO:0005886	plasma membrane	CYBRD1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	CYBRD1	IDA		Human	PMID:17068337
Biological Process	GO:0140576	ascorbate homeostasis	CYBRD1	IDA		Human	PMID:17068337
Biological Process	GO:0006879	intracellular iron ion homeostasis	CYBRD1	IDA		Human	PMID:14499595
Biological Process	GO:0060586	multicellular organismal-level iron ion homeostasis	CYBRD1	IDA		Human	PMID:30272000
Biological Process	GO:0010039	response to iron ion	Cybrd1	IDA		Mouse	PMID:11230685

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern