Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Cyfip1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes CYFIP1
- Mouse genes Cyfip1
- Rat genes Cyfip1
- Zfish genes cyfip1
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cyfip1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	CYFIP1	IPI	UniProtKB:Q06787	Human	PMID:11438699
Molecular Function	GO:0005515	protein binding	CYFIP1	IPI	UniProtKB:Q9Y2A7	Human	PMID:15294869
Molecular Function	GO:0005515	protein binding	CYFIP1	IPI	UniProtKB:Q9Y2A7	Human	PMID:15296760
Molecular Function	GO:0005515	protein binding	CYFIP1	IPI	UniProtKB:Q16555	Human	PMID:16260607
Molecular Function	GO:0005515	protein binding	CYFIP1	IPI	UniProtKB:P63073	Human	PMID:18805096
Molecular Function	GO:0005515	protein binding	CYFIP1	IPI	UniProtKB:Q9Y2A7	Human	PMID:19363480
Molecular Function	GO:0005515	protein binding	CYFIP1	IPI	UniProtKB:Q9Y2A7	Human	PMID:21107423
Molecular Function	GO:0005515	protein binding	CYFIP1	IPI	UniProtKB:B1Q236,UniProtKB:Q8WUW1,UniProtKB:Q92558,UniProtKB:Q9NYB9,UniProtKB:Q9Y2A7	Human	PMID:24439377
Molecular Function	GO:0005515	protein binding	CYFIP1	IPI	UniProtKB:O14901	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CYFIP1	IPI	UniProtKB:O60333-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CYFIP1	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CYFIP1	IPI	UniProtKB:P01023	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CYFIP1	IPI	UniProtKB:P07196	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CYFIP1	IPI	UniProtKB:P51608	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CYFIP1	IPI	UniProtKB:Q7Z699	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Cyfip1	IPI	UniProtKB:P35922	Mouse	MGI:MGI:3036554\|PMID:11438699
Molecular Function	GO:0005515	protein binding	Cyfip1	IPI	UniProtKB:B1Q236,UniProtKB:Q8R5H6	Mouse	MGI:MGI:5688823\|PMID:24439377
Molecular Function	GO:0005515	protein binding	Cyfip1	IPI	UniProtKB:P35922\|UniProtKB:P63073	Mouse	MGI:MGI:4418608\|PMID:18805096
Molecular Function	GO:0005515	protein binding	Cyfip1	IPI	UniProtKB:Q8BHE4	Mouse	MGI:MGI:5825407\|PMID:27605705
Molecular Function	GO:0005515	protein binding	Cyfip1	IPI	UniProtKB:P63073	Mouse	MGI:MGI:4418608\|PMID:18805096
Molecular Function	GO:0005515	protein binding	Cyfip1	IPI	UniProtKB:Q5DU14\|UniProtKB:Q6PFX7\|UniProtKB:Q8BM65	Mouse	MGI:MGI:5304984\|PMID:21946561
Molecular Function	GO:0000340	RNA 7-methylguanosine cap binding	Cyfip1	IDA		Rat	PMID:25453757\|RGD:11558007
Molecular Function	GO:0031267	small GTPase binding	CYFIP1	IMP		Human	PMID:21107423
Molecular Function	GO:0045182	translation regulator activity	Cyfip1	EXP		Mouse	PMID:24050404
Molecular Function	GO:0045182	translation regulator activity	Cyfip1	IDA		Mouse	PMID:24050404
Molecular Function	GO:0045182	translation regulator activity	Cyfip1	IPI		Mouse	PMID:24050404
Molecular Function	GO:0045182	translation regulator activity	Cyfip1	IMP		Mouse	PMID:24050404
Molecular Function	GO:0045182	translation regulator activity	Cyfip1	IEP		Mouse	PMID:24050404
Cellular Component	GO:0044295	axonal growth cone	Cyfip1	IDA		Rat	PMID:16260607\|RGD:11557987
Cellular Component	GO:0090724	central region of growth cone	Cyfip1	IDA		Rat	PMID:16260607\|RGD:11557987
Cellular Component	GO:0005737	cytoplasm	Cyfip1	IDA		Rat	PMID:26000921\|RGD:11568065
Cellular Component	GO:0044294	dendritic growth cone	Cyfip1	IDA		Rat	PMID:16260607\|RGD:11557987
Cellular Component	GO:0043197	dendritic spine	Cyfip1	IDA		Rat	PMID:24667445\|RGD:11568064
Cellular Component	GO:0060076	excitatory synapse	Cyfip1	IDA		Rat	PMID:24667445\|RGD:11568064
Cellular Component	GO:0070062	extracellular exosome	CYFIP1	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	CYFIP1	HDA		Human	PMID:23533145
Cellular Component	GO:0032433	filopodium tip	Cyfip1	IDA		Rat	PMID:16260607\|RGD:11557987
Cellular Component	GO:0005925	focal adhesion	CYFIP1	HDA		Human	PMID:21423176
Cellular Component	GO:0030027	lamellipodium	Cyfip1	IDA		Mouse	PMID:14765121
Cellular Component	GO:0005845	mRNA cap binding complex	Cyfip1	IDA		Mouse	MGI:MGI:4418608\|PMID:18805096
Cellular Component	GO:0043005	neuron projection	Cyfip1	IDA		Mouse	MGI:MGI:3036554\|PMID:11438699
Cellular Component	GO:0043025	neuronal cell body	Cyfip1	IDA		Rat	PMID:16260607\|RGD:11557987
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Cyfip1	IDA		Mouse	MGI:MGI:3036554\|PMID:11438699
Cellular Component	GO:0090725	peripheral region of growth cone	Cyfip1	IDA		Rat	PMID:16260607\|RGD:11557987
Cellular Component	GO:0098794	postsynapse	Cyfip1	IDA		Mouse	PMID:24050404
Cellular Component	GO:0031209	SCAR complex	CYFIP1	IMP		Human	PMID:21107423
Cellular Component	GO:0043195	terminal bouton	Cyfip1	IDA		Rat	PMID:26843638\|RGD:11342679
Biological Process	GO:0048675	axon extension	CYFIP1	IMP		Human	PMID:16260607
Biological Process	GO:0048675	axon extension	cyfip1	IMP	ZFIN:ZDB-CRISPR-191120-4	Zfish	PMID:29518358
Biological Process	GO:0032869	cellular response to insulin stimulus	Cyfip1	IMP		Rat	PMID:16260607\|RGD:11557987
Biological Process	GO:0050890	cognition	CYFIP1	IMP		Human	PMID:17519220
Biological Process	GO:0097484	dendrite extension	Cyfip1	IMP		Mouse	MGI:MGI:5825407\|PMID:27605705
Biological Process	GO:0030032	lamellipodium assembly	Cyfip1	IDA		Mouse	PMID:14765121
Biological Process	GO:0099563	modification of synaptic structure	Cyfip1	IMP		Mouse	MGI:MGI:5515833\|PMID:24050404
Biological Process	GO:1903422	negative regulation of synaptic vesicle recycling	Cyfip1	IMP		Rat	PMID:26843638\|RGD:11342679
Biological Process	GO:0031175	neuron projection development	Cyfip1	IMP		Mouse	MGI:MGI:5825407\|PMID:27605705
Biological Process	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation	CYFIP1	IMP		Human	PMID:21107423
Biological Process	GO:0045773	positive regulation of axon extension	Cyfip1	IMP		Rat	PMID:16260607\|RGD:11557987
Biological Process	GO:0050772	positive regulation of axonogenesis	Cyfip1	IMP		Rat	PMID:16260607\|RGD:11557987
Biological Process	GO:1900006	positive regulation of dendrite development	Cyfip1	IMP		Rat	PMID:16260607\|RGD:11557987
Biological Process	GO:0010592	positive regulation of lamellipodium assembly	CYFIP1	IDA		Human	PMID:21107423
Biological Process	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway	Cyfip1	IMP		Mouse	MGI:MGI:5825407\|PMID:27605705
Biological Process	GO:1900029	positive regulation of ruffle assembly	Cyfip1	IMP		Rat	PMID:16260607\|RGD:11557987
Biological Process	GO:0016601	Rac protein signal transduction	CYFIP1	IMP		Human	PMID:21107423
Biological Process	GO:1905274	regulation of modification of postsynaptic actin cytoskeleton	Cyfip1	IMP		Mouse	PMID:24050404
Biological Process	GO:1905274	regulation of modification of postsynaptic actin cytoskeleton	Cyfip1	IDA		Mouse	PMID:24050404
Biological Process	GO:0031641	regulation of myelination	Cyfip1	IMP		Rat	PMID:31371763\|RGD:14981598
Biological Process	GO:0006417	regulation of translation	Cyfip1	IMP		Mouse	MGI:MGI:5515833\|PMID:24050404
Biological Process	GO:0099578	regulation of translation at postsynapse, modulating synaptic transmission	Cyfip1	IPI		Mouse	PMID:24050404
Biological Process	GO:0099578	regulation of translation at postsynapse, modulating synaptic transmission	Cyfip1	EXP		Mouse	PMID:24050404
Biological Process	GO:0099578	regulation of translation at postsynapse, modulating synaptic transmission	Cyfip1	IDA		Mouse	PMID:24050404
Biological Process	GO:0099578	regulation of translation at postsynapse, modulating synaptic transmission	Cyfip1	IMP		Mouse	PMID:24050404
Biological Process	GO:0099578	regulation of translation at postsynapse, modulating synaptic transmission	Cyfip1	IEP		Mouse	PMID:24050404
Biological Process	GO:0051602	response to electrical stimulus	Cyfip1	IDA		Rat	PMID:25453757\|RGD:11558007

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.