Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CYP26B1
  • Mouse genes Cyp26b1
  • Rat genes Cyp26b1
  • Zfish genes cyp26b1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cyp26b1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	CYP26B1	IDA		Human	PMID:26937021
Molecular Function	GO:0005515	protein binding	CYP26B1	IPI	UniProtKB:Q8WXH2	Human	PMID:32814053
Molecular Function	GO:0008401	retinoic acid 4-hydroxylase activity	CYP26B1	IDA		Human	PMID:10823918
Molecular Function	GO:0008401	retinoic acid 4-hydroxylase activity	Cyp26b1	IMP		Rat	PMID:14592467|RGD:6771357
Molecular Function	GO:0001972	retinoic acid binding	CYP26B1	IDA		Human	PMID:10823918
Cellular Component	GO:0005737	cytoplasm	CYP26B1	IDA		Human	PMID:22899867
Biological Process	GO:0060349	bone morphogenesis	CYP26B1	IMP		Human	PMID:22019272
Biological Process	GO:0060349	bone morphogenesis	cyp26b1	IMP	ZFIN:ZDB-GENO-090415-1	Zfish	PMID:22019272
Biological Process	GO:0060536	cartilage morphogenesis	cyp26b1	IMP	ZFIN:ZDB-GENO-980202-1550	Zfish	PMID:9007254
Biological Process	GO:0060536	cartilage morphogenesis	cyp26b1	IMP	ZFIN:ZDB-GENO-980202-1550	Zfish	PMID:22019272
Biological Process	GO:0001709	cell fate determination	Cyp26b1	IMP	MGI:MGI:3039046	Mouse	PMID:16574820
Biological Process	GO:0071300	cellular response to retinoic acid	Cyp26b1	IEP		Mouse	MGI:MGI:3809313|PMID:18816858
Biological Process	GO:0070268	cornification	Cyp26b1	IMP	MGI:MGI:3039046	Mouse	PMID:22366455
Biological Process	GO:0060365	coronal suture morphogenesis	cyp26b1	IMP	ZFIN:ZDB-GENO-090415-1	Zfish	PMID:22019272
Biological Process	GO:0060363	cranial suture morphogenesis	cyp26b1	IMP	ZFIN:ZDB-GENO-090415-1	Zfish	PMID:22019272
Biological Process	GO:0048701	embryonic cranial skeleton morphogenesis	cyp26b1	IMP	ZFIN:ZDB-GENO-980202-1550	Zfish	PMID:18927157
Biological Process	GO:0048701	embryonic cranial skeleton morphogenesis	cyp26b1	IMP	ZFIN:ZDB-MRPHLNO-090417-1	Zfish	PMID:18927157
Biological Process	GO:0030326	embryonic limb morphogenesis	Cyp26b1	IMP	MGI:MGI:3039046	Mouse	PMID:15030763
Biological Process	GO:0061436	establishment of skin barrier	Cyp26b1	IMP	MGI:MGI:3039046	Mouse	PMID:22366455
Biological Process	GO:0001768	establishment of T cell polarity	Cyp26b1	IMP	MGI:MGI:3764691	Mouse	PMID:23991089
Biological Process	GO:0060323	head morphogenesis	cyp26b1	IMP	ZFIN:ZDB-GENO-090415-1	Zfish	PMID:22019272
Biological Process	GO:0030902	hindbrain development	cyp26b1	IGI	ZFIN:ZDB-GENO-070411-2,ZFIN:ZDB-MRPHLNO-070410-1,ZFIN:ZDB-MRPHLNO-070410-6	Zfish	PMID:17164423
Biological Process	GO:0006954	inflammatory response	Cyp26b1	IMP	MGI:MGI:3764691	Mouse	PMID:23991089
Biological Process	GO:0001822	kidney development	Cyp26b1	IEP		Rat	PMID:15567713|RGD:2306322
Biological Process	GO:0007140	male meiotic nuclear division	Cyp26b1	IMP	MGI:MGI:3039046	Mouse	PMID:16574820
Biological Process	GO:0048387	negative regulation of retinoic acid receptor signaling pathway	Cyp26b1	IMP	MGI:MGI:3039046	Mouse	PMID:22366455
Biological Process	GO:0048387	negative regulation of retinoic acid receptor signaling pathway	cyp26b1	IDA		Zfish	PMID:15661642|ZFIN:ZDB-PUB-050125-11
Biological Process	GO:0048387	negative regulation of retinoic acid receptor signaling pathway	cyp26b1	IDA		Zfish	PMID:15661642
Biological Process	GO:0042476	odontogenesis	cyp26b1	IMP	ZFIN:ZDB-GENO-120131-32	Zfish	PMID:25652838
Biological Process	GO:0010628	positive regulation of gene expression	Cyp26b1	IMP		Mouse	MGI:MGI:3809313|PMID:18816858
Biological Process	GO:2001037	positive regulation of tongue muscle cell differentiation	Cyp26b1	IMP		Mouse	MGI:MGI:3809313|PMID:18816858
Biological Process	GO:0009954	proximal/distal pattern formation	Cyp26b1	IMP	MGI:MGI:3039046	Mouse	PMID:15030763
Biological Process	GO:0030278	regulation of ossification	cyp26b1	IMP	ZFIN:ZDB-GENO-980202-1550	Zfish	PMID:18927157
Biological Process	GO:0030278	regulation of ossification	cyp26b1	IMP	ZFIN:ZDB-GENO-090415-1	Zfish	PMID:18927155
Biological Process	GO:0030278	regulation of ossification	cyp26b1	IMP	ZFIN:ZDB-MRPHLNO-090417-1	Zfish	PMID:18927157
Biological Process	GO:0048385	regulation of retinoic acid receptor signaling pathway	Cyp26b1	IMP	MGI:MGI:3764691	Mouse	PMID:23991089
Biological Process	GO:0045580	regulation of T cell differentiation	Cyp26b1	IMP	MGI:MGI:3764691	Mouse	PMID:23991089
Biological Process	GO:0032526	response to retinoic acid	Cyp26b1	IEP		Rat	PMID:19700416|RGD:6484694
Biological Process	GO:0033189	response to vitamin A	Cyp26b1	IEP		Rat	PMID:19700416|RGD:6484694
Biological Process	GO:0034653	retinoic acid catabolic process	CYP26B1	IDA		Human	PMID:10823918
Biological Process	GO:0034653	retinoic acid catabolic process	Cyp26b1	IMP		Rat	PMID:21138835|RGD:6771354
Biological Process	GO:0034653	retinoic acid catabolic process	cyp26b1	IMP		Zfish	PMID:18927157
Biological Process	GO:0034653	retinoic acid catabolic process	cyp26b1	IMP		Zfish	PMID:18927155
Biological Process	GO:0042573	retinoic acid metabolic process	CYP26B1	IDA		Human	PMID:22020119
Biological Process	GO:0048384	retinoic acid receptor signaling pathway	Cyp26b1	IMP		Mouse	MGI:MGI:3809313|PMID:18816858
Biological Process	GO:0048384	retinoic acid receptor signaling pathway	Cyp26b1	IDA		Mouse	PMID:16554478
Biological Process	GO:0048384	retinoic acid receptor signaling pathway	Cyp26b1	IMP	MGI:MGI:3039046	Mouse	PMID:22366455
Biological Process	GO:0048384	retinoic acid receptor signaling pathway	Cyp26b1	IDA		Mouse	PMID:15030763
Biological Process	GO:0021661	rhombomere 4 morphogenesis	cyp26b1	IGI	ZFIN:ZDB-GENO-070411-2,ZFIN:ZDB-MRPHLNO-070410-1	Zfish	PMID:17164423
Biological Process	GO:0021661	rhombomere 4 morphogenesis	cyp26b1	IGI	ZFIN:ZDB-GENO-070411-2,ZFIN:ZDB-MRPHLNO-070410-1,ZFIN:ZDB-MRPHLNO-070410-6	Zfish	PMID:17164423
Biological Process	GO:0007283	spermatogenesis	Cyp26b1	IMP	MGI:MGI:3039046	Mouse	PMID:16574820
Biological Process	GO:0035992	tendon formation	cyp26b1	IMP	ZFIN:ZDB-GENO-180925-4	Zfish	PMID:29227993
Biological Process	GO:0043587	tongue morphogenesis	Cyp26b1	IMP		Mouse	MGI:MGI:3809313|PMID:18816858
Biological Process	GO:0006805	xenobiotic metabolic process	CYP26B1	IDA		Human	PMID:26937021

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern