Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CYP2J2
  • Mouse genes Cyp2j6
  • Rat genes Cyp2j4
  • Zfish genes cyp2ad2,cyp2ad3,cyp2ad6,cyp2ae1,cyp2j20,cyp2n13,cyp2p10,cyp2p6,cyp2p7,cyp2p8,cyp2p9,cyp2v1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cyp2j6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008405	arachidonic acid 11,12-epoxygenase activity	CYP2J2	IDA		Human	PMID:11901223
Molecular Function	GO:0008404	arachidonic acid 14,15-epoxygenase activity	CYP2J2	IDA		Human	PMID:11901223
Molecular Function	GO:0008392	arachidonic acid epoxygenase activity	CYP2J2	IDA		Human	PMID:11901223
Molecular Function	GO:0008392	arachidonic acid epoxygenase activity	CYP2J2	IDA		Human	PMID:8631948
Molecular Function	GO:0008392	arachidonic acid epoxygenase activity	Cyp2j6	IMP	MGI:MGI:3851346	Mouse	PMID:15256482
Molecular Function	GO:0008391	arachidonic acid monooxygenase activity	Cyp2j4	IDA		Rat	PMID:9143331|RGD:632631
Molecular Function	GO:0016853	isomerase activity	CYP2J2	IDA		Human	PMID:19737933
Molecular Function	GO:0071614	linoleic acid epoxygenase activity	CYP2J2	IDA		Human	PMID:11901223
Molecular Function	GO:0003958	NADPH-hemoprotein reductase activity	Cyp2j4	IDA		Rat	PMID:9143331|RGD:632631
Cellular Component	GO:0005783	endoplasmic reticulum	Cyp2j6	IDA		Mouse	PMID:19801493
Cellular Component	GO:0005789	endoplasmic reticulum membrane	Cyp2j4	IDA		Rat	PMID:9143331|RGD:632631
Cellular Component	GO:0070062	extracellular exosome	CYP2J2	HDA		Human	PMID:18570454
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	Cyp2j4	IDA		Rat	PMID:12882760|RGD:1299258
Biological Process	GO:0019369	arachidonic acid metabolic process	Cyp2j4	IDA		Rat	PMID:9143331|RGD:632631
Biological Process	GO:0019373	epoxygenase P450 pathway	CYP2J2	IDA		Human	PMID:11901223
Biological Process	GO:0019373	epoxygenase P450 pathway	CYP2J2	IDA		Human	PMID:8631948
Biological Process	GO:0007565	female pregnancy	Cyp2j4	IEP		Rat	PMID:17138762|RGD:7243140
Biological Process	GO:0006690	icosanoid metabolic process	CYP2J2	IDA		Human	PMID:19737933
Biological Process	GO:0043651	linoleic acid metabolic process	CYP2J2	IDA		Human	PMID:11901223
Biological Process	GO:0032966	negative regulation of collagen biosynthetic process	Cyp2j4	IMP		Rat	PMID:25840911|RGD:12904676
Biological Process	GO:0032966	negative regulation of collagen biosynthetic process	Cyp2j4	IMP		Rat	PMID:29656108|RGD:150520032
Biological Process	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway	Cyp2j4	IMP		Rat	PMID:25840911|RGD:12904676
Biological Process	GO:1903055	positive regulation of extracellular matrix organization	Cyp2j4	IMP		Rat	PMID:29656108|RGD:150520032
Biological Process	GO:0045722	positive regulation of gluconeogenesis	Cyp2j4	IMP		Rat	PMID:29656108|RGD:150520032
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	Cyp2j4	IMP		Rat	PMID:25840911|RGD:12904676
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	Cyp2j4	IMP		Rat	PMID:29656108|RGD:150520032
Biological Process	GO:0014070	response to organic cyclic compound	Cyp2j4	IEP		Rat	PMID:10497137|RGD:1625387
Biological Process	GO:0001523	retinoid metabolic process	Cyp2j4	IDA		Rat	PMID:9606960|RGD:1625388

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern