Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CYSLTR2
  • Mouse genes Cysltr2
  • Rat genes Cysltr2
  • Zfish genes cysltr2a,cysltr2b,cysltr3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cysltr2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001631	cysteinyl leukotriene receptor activity	Cysltr2	IDA		Mouse	PMID:11854273
Molecular Function	GO:0001631	cysteinyl leukotriene receptor activity	Cysltr2	IDA		Mouse	PMID:11591709
Molecular Function	GO:0005515	protein binding	CYSLTR2	IPI	UniProtKB:Q12959	Human	PMID:21525870
Molecular Function	GO:0005515	protein binding	CYSLTR2	IPI	UniProtKB:Q12959	Human	PMID:24550280
Molecular Function	GO:0005515	protein binding	CYSLTR2	IPI	UniProtKB:Q12959	Human	PMID:26617989
Molecular Function	GO:0005515	protein binding	CYSLTR2	IPI	UniProtKB:Q12959	Human	PMID:30126976
Molecular Function	GO:0005515	protein binding	CYSLTR2	IPI	UniProtKB:Q14160	Human	PMID:30126976
Molecular Function	GO:0005515	protein binding	CYSLTR2	IPI	UniProtKB:Q07627	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYSLTR2	IPI	UniProtKB:Q5JR59-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYSLTR2	IPI	UniProtKB:Q8TBB1	Human	PMID:32296183
Cellular Component	GO:0016020	membrane	Cysltr2	IDA		Mouse	PMID:11591709
Biological Process	GO:0090650	cellular response to oxygen-glucose deprivation	Cysltr2	IEP		Rat	PMID:17910051|RGD:5144007
Biological Process	GO:0060253	negative regulation of glial cell proliferation	Cysltr2	IMP		Rat	PMID:17910051|RGD:5144007
Biological Process	GO:0045766	positive regulation of angiogenesis	Cysltr2	IMP		Rat	PMID:21105577|RGD:5144005
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	Cysltr2	IMP		Rat	PMID:21055410|RGD:5144006

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern